Search Results - "A. A. Ostanin"
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Expression of checkpoint molecules by regulatory T cells in multiple myeloma
Published in Medit͡s︡inskai͡a︡ immunologii͡a (21-09-2024)“…In multiple myeloma (MM), the content of T lymphocytes expressing “checkpoint” molecules PD-1, TIM-3, LAG-3, etc. is increased. Regulatory T cells (Treg) can…”
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Clinical suitability of intranasal delivery of M2 macrophage soluble factors in patients with post-COVID olfactory disorders
Published in European psychiatry (01-08-2024)“…IntroductionSARS-CoV virus showed transneuronal penetration through the olfactory bulb resulting in the rapid intracranial spread. So, olfactory dysfunction is…”
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M2 macrophage-derived soluble factors enhance neuronal density in the frontal cortex of depression-like mice
Published in European psychiatry (01-08-2024)“…IntroductionChronic inflammation in depression is associated with decreased levels of neurotrpohic factors and suppressed neurogenesis. We have previously…”
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4
Fibrogenic and fibrolytic potential of differently activated human macrophages
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…Macrophages are involved in the regulation of fibrogenesis and turnover of the extracellular matrix. One way to perform this function is through the production…”
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Safety and Therapeutic Potential of M2 Macrophages in Stroke Treatment
Published in Cell transplantation (01-08-2016)“…Our objective was to evaluate the safety and clinical efficacy of autologous M2 macrophage transplantation in nonacute stroke patients. We also evaluated…”
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Effect of soluble factors of macrophages polarized by efferocytosis on neuronal density in the frontal cortex and hippocampus of mice in a model of stress-induced depression
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…Recently, there has been a steady increase in depressive disorders, which occupy an important place in the structure of the causes of disability. In the…”
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Human type 2 macrophages biologically active soluble products in the editing of stress-induced depressive-like behavior
Published in European psychiatry (01-04-2021)“…Introduction In the scientific world widely discussed phenomenon of “cytokine-induced depression”. Macrophages have high plasticity and are able to control the…”
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Intranasal immunotherapy with M2 macrophage soluble factors in post-COVID hyposmia: A pilot study
Published in International immunopharmacology (05-01-2024)“…Olfactory dysfunction is an early marker of COVID-19 infection. However, individuals may develop chronic olfactory impairment for more than six months in…”
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M-CSF and GM-CSF determinate fibromodulatory activity of polarized human macrophages
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-11-2022)“…GM-CSF and M-CSF, the hematopoietic colony-stimulating factors, induce various phenotypic changes in macrophage lineage populations and promote cell…”
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10
Influence of Interpenetrating Chains on Rigid Domain Dimensions in Siloxane-Based Block-Copolymers
Published in Polymers (27-09-2022)“…1H spin-diffusion solid-state NMR was utilized to elucidate the domain size in multiblock-copolymers (BCPs) poly-(block poly(dimethylsiloxane)-block…”
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11
Angiogenin as a Possible Mediator of Macrophage-Mediated Regulation of Fibroblast Functions
Published in Bulletin of experimental biology and medicine (01-09-2023)“…We studied angiogenin production by human macrophages and evaluated the role of this factor in the macrophage-mediated regulation of fibroblasts. All…”
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The Molecular Aspects of Functional Activity of Macrophage-Activating Factor GcMAF
Published in International journal of molecular sciences (12-12-2023)“…Group-specific component macrophage-activating factor (GcMAF) is the vitamin D -binding protein (DBP) deglycosylated at Thr . The protein is believed to…”
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The Macrophage Activator GcMAF-RF Enhances the Antitumor Effect of Karanahan Technology through Induction of M2–M1 Macrophage Reprogramming
Published in Journal of immunology research (29-02-2024)“…Macrophages are the immune cells of high-immunological plasticity, which can exert both pro- and anti-inflammatory activity, as well as repolarize their…”
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Common Ɣ-chain cytokine receptors as functional phenotype markers of PD-1and TIM-3-positive T cells in multiple myeloma
Published in Sibirskiĭ onkologicheskiĭ zhurnal (22-02-2023)“…T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However,…”
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The New General Biological Property of Stem-like Tumor Cells (Part II: Surface Molecules, Which Belongs to Distinctive Groups with Particular Functions, Form a Unique Pattern Characteristic of a Certain Type of Tumor Stem-like Cells)
Published in International journal of molecular sciences (13-12-2022)“…An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs), to internalize extracellular double-stranded DNA…”
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Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation
Published in Sibirskiĭ onkologicheskiĭ zhurnal (01-01-2023)“…Introduction . Myeloid-derived suppressor cells (MDSCs) play an important role in restriction of the immune response and are associated with a poor prognosis…”
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Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity
Published in International journal of molecular sciences (22-07-2022)“…The main problem related to the studies focusing on group-specific component protein-derived macrophage-activating factor (GcMAF) is the lack of clarity about…”
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Impact of Double-Stranded RNA Internalization on Hematopoietic Progenitors and Krebs-2 Cells and Mechanism
Published in International journal of molecular sciences (01-03-2023)“…It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this…”
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Production of GcMAF with Anti-Inflammatory Properties and Its Effect on Models of Induced Arthritis in Mice and Cystitis in Rats
Published in Current issues in molecular biology (28-09-2024)“…Vitamin D transporter (DBP) is a multifunctional protein. Site-specific deglycosylation results in its conversion to group-specific component protein-derived…”
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Interplay of Structural Factors in Formation of Microphase-Separated or Microphase-Mixed Structures of Polyurethanes Revealed by Solid-State NMR and Dielectric Spectroscopy
Published in Polymers (14-06-2021)“…A set of aromatic-oxyaliphatic polyurethanes (PUs) with different mass fractions of components also containing fluorinated fragments was synthesized and…”
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