Search Results - "A. A. Elkanzi, Nadia"
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Pumice as a Novel Natural Heterogeneous Catalyst for the Designation of 3,4-Dihydropyrimidine-2-(1H)-ones/thiones under Solvent-Free Conditions
Published in Molecules (Basel, Switzerland) (01-09-2022)“…In this study, pumice is used as a novel natural heterogeneous catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones via the one-pot…”
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Facile One-Pot Multicomponent Synthesis of Pyrazolo-Thiazole Substituted Pyridines with Potential Anti-Proliferative Activity: Synthesis, In Vitro and In Silico Studies
Published in Molecules (Basel, Switzerland) (22-05-2021)“…Pyrazolothiazole-substituted pyridine conjugates are an important class of heterocyclic compounds with an extensive variety of potential applications in the…”
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New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study
Published in Molecules (Basel, Switzerland) (29-01-2021)“…In an effort to improve and achieve biologically active anticancer agents, a novel series of 1,2,3-triazole-containing hybrids were designed and efficiently…”
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Design, Synthesis, and SAR Studies of Some Novel Chalcone Derivatives for Potential Insecticidal Bioefficacy Screening on Spodoptera frugiperda (Lepidoptera: Noctuidae)
Published in ACS omega (08-11-2022)“…Spodoptera frugiperda is a species of the order Lepidoptera. It is one of the species of fall armyworm moths distinguished by its larval life stage, is found…”
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Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1- c ][1,2,4]triazolo[3,4- f ][1,2,4]triazines
Published in Molecules (Basel, Switzerland) (15-03-2020)“…A series of 34 new pyrimido[2,1- ][1,2,4]triazine-3,4-diones were synthesized and fully characterized using IR, NMR, MS, and microanalytical analysis. In vitro…”
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Efficient and Recoverable Bio-Organic Catalyst Cysteine for Synthesis, Docking Study, and Antifungal Activity of New Bio-Active 3,4-Dihydropyrimidin-2(1H)‑ones/thiones Under Microwave Irradiation
Published in ACS omega (05-07-2022)“…An eco-friendly green bio-organic catalyst and low-cost 3,4-dihydropyrimidin-2(1H)-ones/thione derivatives 4–7 have been synthesized using a high-yield,…”
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An Efficient Synthetic Approach Towards Benzo[ b ]pyrano[2,3- e ][1,4]diazepines, and Their Cytotoxic Activity
Published in Molecules (Basel, Switzerland) (28-04-2020)“…In search of unprecedented tri and/or tetrapod pharmacophoric conjugates, a series of 32 new 4-ethyl-1 -benzo[ ][1,4]diazepin-2(3 )-ones were synthesized and…”
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New Benzimidazole‐Based Fe (III) and Cr (III) Complexes: Characterization, Bioactivity Screening, and Theoretical Implementations Using DFT and Molecular Docking Analysis
Published in Applied organometallic chemistry (01-11-2022)“…Two new Fe (III) and Cr (III) complexes had been synthesized and structurally characterized. The new complexes were based on 2‐methyl‐benzimidazole (MB) and…”
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Synthesis of Chalcones Derivatives and Their Biological Activities: A Review
Published in ACS omega (16-08-2022)“…Chalcone derivatives are considered valuable species because they possess a ketoethylenic moiety, CO–CHCH–. Due to the presence of a reactive α,β-unsaturated…”
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New mononuclear Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) complexes incorporating 4‐{[(2 hydroxyphenyl)imino]methyl}phenyl‐4‐methylbenzenesulfonate (HL): Synthesis, characterization, theoretical, anti‐inflammatory, and molecular docking investigation
Published in Applied organometallic chemistry (01-05-2022)“…Herein, new Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) complexes incorporating 4‐{[(2‐hydroxyphenyl)imino]methyl}phenyl 4‐methylbenzenesulfonate Schiff‐base…”
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A novel colorimetric chemosensor based on 2-[(carbamothioylhydrazono) methyl]phenyl 4-methylbenzenesulfonate (CHMPMBS) for the detection of Cu(II) in aqueous medium
Published in Research on chemical intermediates (01-05-2023)“…In this study, 2-[(carbamothioylhydrazono)methyl-phenyl-4-methylbenzenesulfonate (CHMPMBS) , which exhibits selective colorimetric chemosensor properties for…”
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Preparation of some novel thiazolidinones, imidazolinones, and azetidinone bearing pyridine and pyrimidine moieties with antimicrobial activity
Published in Journal of heterocyclic chemistry (01-07-2020)“…By aiming to design new antimicrobial agents, we prepared new series of thiazolidin‐4‐ones(12a–d), imidazolin‐4‐ones(13a–d), and azetidin‐2‐ones (14a–d),…”
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A selective colorimetric chemosensor for detecting Ni(II) in aqueous solutions based on 4-[{[4-(3-chlorophenyl)-1,3-thiazol-2-yl]hydrazono}methyl]phenyl 4-methyl benzene sulfonate (CTHMBS)
Published in Analytical sciences (01-04-2024)“…Among the toxic heavy metals, Ni(II) can cause a variety of side effects on human health, such as allergy, cardiovascular and kidney diseases, lung fibrosis,…”
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Construction and Docking Studies of Novel Pyrimido[4,5‐b]quinolines as Antimicrobial Agents
Published in Chemistry & biodiversity (01-06-2024)“…In order to develop novel antimicrobial agents, we prepared quinoline bearing pyrimidine analogues 2–7, 8 a–d and 9 a–d and their structures were elucidated by…”
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Review of the recent advances of pyrazole derivatives as selective COX-2 inhibitors for treating inflammation
Published in Molecular diversity (16-07-2024)“…Pyrazole heterocycle is regarded as an extremely significant agent for the therapy of inflammation. Celecoxib, lonazolac, deracoxib, and phenylbutazone are…”
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Antioxidant and Antimicrobial Potential of 1,8‐Naphthyridine Based Scaffolds: Design, Synthesis and in Silico Simulation Studies within Topoisomerase II
Published in Chemistry & biodiversity (01-06-2024)“…A series of spiro β‐Lactams (4 a–c, 7 a–c) and thiazolidinones (5 a–c, 8 a–c) possessing 1,8‐naphthyridine moiety were synthesized in this study. The structure…”
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A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives
Published in Archiv der Pharmazie (Weinheim) (01-08-2024)“…Quinazoline and quinazolinone derivatives piqued medicinal chemistry interest in developing novel drug candidates owing to their pharmacological potential…”
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Design and Synthesis of Pyridine and Thiazole Derivatives as Eco‐friendly Insecticidal to Control Olive Pests
Published in Chemistry & biodiversity (01-07-2023)“…Treatment of p‐tosyloxybenzaldehyde (1) with ethyl cyanoacetate afforded ethyl 2‐cyano‐3‐(4‐{[(4‐methylphenyl)sulfonyl]oxy}phenyl)acrylate (2) which reacted…”
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Design, Synthesis, Molecular Modeling Study, and Antimicrobial Activity of Some Novel Pyrano[2,3‐b]pyridine and Pyrrolo[2,3‐b]pyrano[2.3‐d]pyridine Derivatives
Published in Journal of heterocyclic chemistry (01-02-2019)“…Novel derivatives of pyrano[2,3‐b]pyridine and pyrrolo[2,3‐b]pyrano[2.3‐d]pyridine were prepared, and their structures were elucidated by spectral and…”
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