Search Results - "A Sahebkar"
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Preventing cardiovascular heart disease: Promising nutraceutical and non-nutraceutical treatments for cholesterol management
Published in Pharmacological research (01-06-2017)“…[Display omitted] Hypercholesterolemia is one of the major risk factors for the development of cardiovascular disease. Atherosclerosis resulting from…”
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Ceramides and diabetes mellitus: an update on the potential molecular relationships
Published in Diabetic medicine (01-01-2020)“…Recent evidence suggests that ceramides can play an important pathophysiological role in the development of diabetes. Ceramides are primarily recognized as…”
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Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial
Published in Drug research (01-11-2015)“…Pulmonary problems are among the most frequent chronic complications of sulfur mustard (SM) intoxication and are often accompanied by deregulated production of…”
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Circulating microRNA-192 as a diagnostic biomarker in human chronic lymphocytic leukemia
Published in Cancer gene therapy (01-10-2016)“…Chronic lymphocytic leukemia (CLL) is known as the most common lymphoid malignancy in the Western world. MicroRNAs (miRNAs) are a class of small noncoding RNAs…”
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Stable and sustained release liposomal formulations of celecoxib: In vitro and in vivo anti-tumor evaluation
Published in International journal of pharmaceutics (05-04-2018)“…[Display omitted] Celecoxib (CLX) is a selective COX-2 inhibitor with anticancer potential in a COX-2 dependent and independent manner. CLX’s low water…”
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Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) concentrations: a systematic review and meta-analysis of clinical trials
Published in Diabetes, obesity & metabolism (01-11-2015)“…Aims To evaluate the magnitude of the effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) levels through a systematic review…”
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The most prevalent side effects of pegylated liposomal doxorubicin monotherapy in women with metastatic breast cancer: a systematic review of clinical trials
Published in Cancer gene therapy (01-05-2017)“…Despite benefits of systemic chemotherapy in breast cancer treatment, several patients with early-stage breast cancer will develop metastatic breast cancer…”
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Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial
Published in Drug research (01-10-2015)“…Osteoarthritis (OA) is a degenerative joint disease associated with inflammation. The present study aimed to determine changes in serum levels of inflammatory…”
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Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
Published in Frontiers in neuroendocrinology (01-01-2019)“…•Selective Estrogen Receptor Modulators (SERMs) exert protective actions in the brain.•SERMs acting on estrogen receptors (ERs) improve the antioxidant defense…”
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Appropriateness of statin prescription in the elderly
Published in European journal of internal medicine (01-04-2018)“…Statins, the most widely used drugs in the Western world, have become a pivotal component in the primary and secondary prevention of vascular diseases…”
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Role of selective peroxisome proliferator-activated receptor modulators in managing cardiometabolic disease: tale of a roller-coaster
Published in Diabetes, obesity & metabolism (01-09-2014)“…Atherogenic dyslipidaemia is a hypertriglyceridaemic phenotype, associated with increased plasma concentrations of small, dense low‐density lipoprotein (sdLDL)…”
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Ameliorative effects of Nigella sativa on dyslipidemia
Published in Journal of endocrinological investigation (01-10-2015)“…Introduction Dyslipidemia is an established risk factor for ischemic heart disease. Nigella sativa ( NS ) is a medicinal plant that has been used for the…”
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Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study
Published in Journal of human hypertension (01-10-2016)“…Hypertension is a major risk factor for cardiovascular disease and has a prevalence of about one billion people worldwide. It has been shown that adherence to…”
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Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo
Published in Phytomedicine (Stuttgart) (01-03-2010)“…A prenylated coumarin (diversin, 1) together with four new sesquiterpene lactones (diversolides A, D, F and G, 2-5) isolated from the roots of Ferula…”
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Standardised mortality ratios in people exposed to sulphur mustard during the Iran–Iraq war: a retrospective study with 39-year follow-up
Published in Public health (London) (01-02-2024)“…Sulphur mustard (SM) is a chemical weapon agent that was extensively used by Iraqi troops during the Iran–Iraq war (1980–1988), resulting in exposure among…”
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PiggyBac as a novel vector in cancer gene therapy: current perspective
Published in Cancer gene therapy (01-02-2016)“…Selection of suitable delivery system is one of the crucial aspects in gene therapy that determines the efficiency of gene therapy. The past two decades have…”
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Paraoxonase-1 activity in patients with cancer: A systematic review and meta-analysis
Published in Critical reviews in oncology/hematology (01-07-2018)“…Paraoxonase-1 (PON1) is a lipolactonase implicated in the elimination of carcinogenic free radicals and in the scavenging mechanisms to maintain oxidative…”
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Antibiotic resistance profiles of Salmonella serotypes isolated from animals in Iran: a meta-analysis
Published in Iranian journal of veterinary research (01-01-2020)“…infection (salmonellosis) is a zoonotic bacterial disease. Widespread use of antibiotics in livestock and poultry production for different purposes such as…”
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The Genetic Spectrum of Familial Hypercholesterolemia (FH) in the Iranian Population
Published in Scientific reports (06-12-2017)“…Familial hypercholesterolemia (FH) is an autosomal dominant disorder associated with premature cardiovascular disease (CVD). Mutations in the LDLR , APOB , and…”
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