Search Results - "A Fielding, Barbara"
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1
Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake
Published in Progress in lipid research (01-09-2008)“…Accurate assessment of fat intake is essential to examine the relationships between diet and disease risk but the process of estimating individual intakes of…”
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2
Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells
Published in The Journal of biological chemistry (15-08-2014)“…Fatty acid-binding protein 4 (FABP4) is an adipogenic protein and is implicated in atherosclerosis, insulin resistance, and cancer. In endothelial cells, FABP4…”
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3
The role of dietary sugars and de novo lipogenesis in non-alcoholic fatty liver disease
Published in Nutrients (10-12-2014)“…Dietary sugar consumption, in particular sugar-sweetened beverages and the monosaccharide fructose, has been linked to the incidence and severity of…”
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4
Mechanisms for the acute effect of fructose on postprandial lipemia
Published in The American journal of clinical nutrition (01-06-2007)“…BACKGROUND: A high fructose intake can lead to postprandial hypertriacylglycerolemia. The underlying mechanism is unclear. OBJECTIVE: The objective of the…”
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5
Starchy Carbohydrates in a Healthy Diet: The Role of the Humble Potato
Published in Nutrients (14-11-2018)“…Potatoes have been an affordable, staple part of the diet for many hundreds of years. Recently however, there has been a decline in consumption, perhaps…”
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Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans
Published in The American journal of clinical nutrition (01-10-2012)“…Background: Cross-sectional studies have identified a high intake of simple sugars as an important dietary factor predicting nonalcoholic fatty liver disease…”
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7
LRP5 Regulates Human Body Fat Distribution by Modulating Adipose Progenitor Biology in a Dose- and Depot-Specific Fashion
Published in Cell metabolism (03-02-2015)“…Common variants in WNT pathway genes have been associated with bone mass and fat distribution, the latter predicting diabetes and cardiovascular disease risk…”
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8
Exercise Prevents Fructose-Induced Hypertriglyceridemia in Healthy Young Subjects
Published in Diabetes (New York, N.Y.) (01-07-2013)“…Excess fructose intake causes hypertriglyceridemia and hepatic insulin resistance in sedentary humans. Since exercise improves insulin sensitivity in…”
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The Effect of Fructose Feeding on Intestinal Triacylglycerol Production and De Novo Fatty Acid Synthesis in Humans
Published in Nutrients (15-06-2020)“…A high fructose intake exacerbates postprandial plasma triacylglycerol (TAG) concentration, an independent risk factor for cardiovascular disease, although it…”
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10
Increased Brain Fatty Acid Uptake in Metabolic Syndrome
Published in Diabetes (New York, N.Y.) (01-09-2010)“…To test whether brain fatty acid uptake is enhanced in obese subjects with metabolic syndrome (MS) and whether weight reduction modifies it. We measured brain…”
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11
Pancreatic Ectopic Fat Is Characterized by Adipocyte Infiltration and Altered Lipid Composition
Published in Obesity (Silver Spring, Md.) (01-03-2008)“…Objective: Sustained exposure to lipids is deleterious for pancreatic islet function. This could be mediated through increased pancreatic fat following…”
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12
Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding
Published in The American journal of clinical nutrition (01-04-2008)“…BACKGROUND:High-carbohydrate (HC) diets increase de novo lipogenesis (DNL), but effects on stearoyl-CoA desaturase (SCD) are not so well studied. OBJECTIVE:The…”
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13
Gluteofemoral Adipose Tissue Plays a Major Role in Production of the Lipokine Palmitoleate in Humans
Published in Diabetes (New York, N.Y.) (01-06-2012)“…The expansion of lower-body adipose tissue (AT) is paradoxically associated with reduced cardiovascular disease and diabetes risk. We examined whether the…”
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14
Oxylipin secretion by human CD3 + T lymphocytes in vitro is modified by the exogenous essential fatty acid ratio and life stage
Published in Frontiers in immunology (14-06-2023)“…Immune function changes across the life stages; for example, senior adults exhibit a tendency towards a weaker cell-mediated immune response and a stronger…”
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Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men
Published in British journal of nutrition (28-03-2011)“…Before the menopause, women are relatively protected against CVD compared with men. The reasons for this sex difference are not completely understood, but…”
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Fatty acid composition and metabolic partitioning of α-linolenic acid are contingent on life stage in human CD3 + T lymphocytes
Published in Frontiers in immunology (13-12-2022)“…Immune function changes across the life course; the fetal immune system is characterised by tolerance while that of seniors is less able to respond effectively…”
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Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men
Published in Diabetes (New York, N.Y.) (01-02-2008)“…Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases…”
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The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism
Published in Frontiers in immunology (05-10-2021)“…Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some…”
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Eicosapentaenoic acid-rich oil supplementation activates PPAR-γ and delays skin wound healing in type 1 diabetic mice
Published in Frontiers in immunology (09-06-2023)“…Delayed wound healing is a devastating complication of diabetes and supplementation with fish oil, a source of anti-inflammatory omega-3 (ω-3) fatty acids…”
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Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period
Published in Diabetes (New York, N.Y.) (01-01-2007)“…Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period Alex S.T. Bickerton 1 , Rachel Roberts 1 , Barbara A…”
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