Search Results - "A El Saadany, Amira"

Metformin ameliorated methotrexate-induced hepatorenal toxicity in rats in addition to its antitumor activity: two birds with one stone by Rizk, Fatma H, Saadany, Amira A El, Dawood, Lamees, Elkaliny, Heba H, Sarhan, Naglaa I, Badawi, Rehab, Abd-Elsalam, Sherief

“…Methotrexate (MTX) is a drug used in treatment of various malignancies. Unfortunately, it leads to life-threatening complications including hepatorenal…”
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The protective effects of topiramate and spirulina against doxorubicin-induced cardiotoxicity in rats by Elmorsi, Radwa M, El Saadany, Amira A, Kabel, Ahmed M, Abou El-Seoud, Samia H

“…Doxorubicin (DOX) is a widely used chemotherapy drug that can cause significant cardiotoxicity, limiting its clinical application. This study aimed to…”
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Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation by Rizk, Fatma H., Soliman, Nema A., Abo-Elnasr, Suzan E., Mahmoud, Heba A., Abdel Ghafar, Muhammad T., Elkholy, Rasha A., ELshora, Ola A., Mariah, Reham A., Amin Mashal, Shaimaa Samir, El Saadany, Amira A.

“…This study aimed to evaluate the potential mitigating effect of fisetin on monosodium glutamate (MSG)-induced testicular toxicity and investigate the possible…”
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Anti-cancer effect of nano-encapsulated boswellic acids, curcumin and naringenin against HepG-2 cell line by Elnawasany, Sally, Haggag, Yusuf A, Shalaby, Shahinaz M, Soliman, Nema A, El Saadany, Amira A, Ibrahim, Marwa A A, Badria, Farid

“…liver cancer is one of the most common cancers in the world. So far, there is no gold standard treatment for hepatocellular carcinoma. We conducted this in…”
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Ameliorating effects of adropin on letrozole‐induced polycystic ovary syndrome via regulating steroidogenesis and the microbiota inflammatory axis in rats by Rizk, Fatma H., El Saadany, Amira A., Elshamy, Amira Mostafa, Abd Ellatif, Rasha A., El‐Guindy, Dina M., Helal, Duaa S., Hamama, Mohamed G., El‐Sharnoby, Jehan Abd El‐Hameed, Abdel Ghafar, Muhammad T., Faheem, Heba

“…Growing evidence supports the role of gut microbiota in chronic inflammation, insulin resistance (IR) and sex hormone production in polycystic ovary syndrome…”
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Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasis by Rizk, Fatma H., El Saadany, Amira A., Atef, Marwa Mohamed, Abd-Ellatif, Rania Nagi, El-Guindy, Dina M., Abdel Ghafar, Muhammad T., Shalaby, Marwa M., Hafez, Yasser Mostafa, Mashal, Shaimaa Samir Amin, Basha, Eman H., Faheem, Heba, Barhoma, Ramez Abd-Elmoneim

“…Growing evidence supports the role of the gut-kidney axis and persistent mitochondrial dysfunction in the pathogenesis of diabetic nephropathy (DN)…”
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Possible mitigating effect of adropin on lung injury in diabetic rats: Targeting the role of Rho A/Rho‐associated kinase pathway by Rizk, Fatma H., El‐Saka, Mervat H., Ibrahim, Rowida Raafat, El‐Deeb, Omnia Safwat, Ibrahim, Hoda A., El Saadany, Amira A., Mashal, Shaimaa S., Ammar, Leila, Abdelsattar, Amal M., Barhoma, Ramez A.

“…This study evaluated possible mitigating effect of adropin on lung injury in diabetic rats, targeting role of Rho A/Rho‐associated kinase pathway. Rats were…”
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Trichinella spiralis: A new parasitic target for curcumin nanoformulas in mice models by Khedr, Safaa Ibrahim, Gomaa, Maha Mohamed, Mogahed, Nermine Mogahed Fawzy Hussien, Gamea, Ghada A., Khodear, Gehan A.M., Sheta, Eman, Soliman, Nada A.H., El Saadany, Amira A., Salama, Amina M.

“…Trichinosis spiralis is a global disease with significant economic impact. Albendazole is the current-treatment. Yet, the world-widely emerging antimicrobial…”
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Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice by Zidan, Amr, EL Saadany, Amira A., El Maghraby, Gamal M., Abdin, Amany A., Hedya, Sabeha E.

“…The aim of this study was to investigate the potential cardioprotective and anti-cancer effects of carvedilol (CAR) either free or as loaded nano-formulated…”
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Crocin lessens desipramine-induced phospholipidosis biomarker levels via targeting oxidative stress- related PI3K/Akt/mTOR signaling pathways in the rat liver by Ahmed El-Sheikh, Amal, A Mahmoud, Heba, Ali El-Kordy, Eman, M Abdelsattar, Amal, H Rizk, Fatma, Mahmoud El-Sharaby, Radwa, S Mashal, Shimaa, A El Saadany, Amira, H Shalaby, Rania, M Elshamy, Amira, Safwat El-Deeb, Omnia, Raafat Ibrahim, Rowida, A Ibrahim, Hoda

“…Background and aim Crocin is a pharmacologically active chemical found in the spice saffron from Crocus sativus L. It possesses antioxidant and anti-radical…”
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Effect of atorvastatin with or without prednisolone on Freund's adjuvant induced-arthritis in rats by Abdin, Amany A., Abd El-Halim, Mahmoud S., Hedeya, Sabiha E., El-Saadany, Amira A.E.

“…Rheumatoid arthritis is a chronic systemic inflammatory disease where cardiovascular diseases have been recognized as major determinants of early morbidity and…”
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