Search Results - "A Algehainy, Naseh"
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Tamarix aphylla derived metabolites ameliorate indomethacin-induced gastric ulcers in rats by modulating the MAPK signaling pathway, alleviating oxidative stress and inflammation: In vivo study supported by pharmacological network analysis
Published in PloS one (10-05-2024)“…Nature has proven to be a treasure resource of bioactive metabolites. In this regard, Tamarix aphylla (F. Tamaricaceae) leaves crude extract was investigated…”
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Antibacterial efficacy of synthesized silver nanoparticles of Microbacterium proteolyticum LA2(R) and Streptomyces rochei LA2(O) against biofilm forming meningitis causing microbes
Published in Scientific reports (13-03-2023)“…Actinobacteria obtained from the least explored Indian regions were studied for their ability to suppress meningitis-causing bacteria in nanoparticle form…”
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Fuzzy Neural Network Expert System with an Improved Gini Index Random Forest-Based Feature Importance Measure Algorithm for Early Diagnosis of Breast Cancer in Saudi Arabia
Published in Big data and cognitive computing (01-03-2022)“…Breast cancer is one of the common malignancies among females in Saudi Arabia and has also been ranked as the one most prevalent and the number two killer…”
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Wound healing potential of Cystoseira/mesenchymal stem cells in immunosuppressed rats supported by overwhelming immuno-inflammatory crosstalk
Published in PloS one (04-04-2024)“…Wound healing, one of the most intricate and dynamic processes of the body, maintains skin integrity following trauma. One of the main issues that still exists…”
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5
New cytotoxic dammarane type saponins from Ziziphus spina-christi
Published in Scientific reports (23-11-2023)“…Cancer is the world's second-leading cause of death. Drug development efforts frequently focus on medicinal plants since they are a valuable source of…”
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Unveiling Lobophytum sp. the neuroprotective potential of Parkinson's disease through multifaceted mechanisms, supported by metabolomic analysis and network pharmacology
Published in Scientific reports (18-09-2024)“…A main feature of neurodegenerative diseases is the loss of neurons. One of the most prevalent neurodegenerative illnesses is Parkinson disease (PD). Although…”
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Egyptian mandarin peel oil's anti-scabies potential via downregulation-of-inflammatory/immune-cross-talk: GC–MS and PPI network studies
Published in Scientific reports (30-08-2023)“…The current study investigated the scabicidal potential of Egyptian mandarin peel oil ( Citrus reticulata Blanco, F. Rutaceae) against sarcoptic…”
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Nutritional Composition and Anti-Type 2 Diabetes Mellitus Potential of Femur Bone Extracts from Bovine, Chicken, Sheep, and Goat: Phytochemical and In Vivo Studies
Published in Nutrients (01-09-2023)“…Nutritional deficits in one’s diet have been established as the key risk factor for T2DM in recent years. Nutritional therapy has been demonstrated to be…”
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Wound Restorative Power of Halimeda macroloba / Mesenchymal Stem Cells in Immunocompromised Rats via Downregulating Inflammatory/Immune Cross Talk
Published in Marine drugs (30-05-2023)“…Impaired skin wound healing is still a major challenge, especially with immunocompromised patients who express delayed healing and are susceptible to…”
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The Protective and Therapeutic Anti-Alzheimer Potential of Olea europaea L. cv. Picual: An In Silico and In Vivo Study
Published in Metabolites (25-11-2022)“…LC-HRESIMS metabolomic profiling of L. cv. Picual (OEP) (Saudi Arabian olive cultivar, F. Oleacea) revealed 18 compounds. Using pharmacology networking to…”
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Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof
Published in Antibiotics (Basel) (27-12-2022)“…Scabies is an invasive skin condition caused by mites. The present study investigates the antiscabies potential of coconut seed extract (CSE) in rabbits. GC-MS…”
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Antiplasmodial potential of phytochemicals from Citrus aurantifolia peels: a comprehensive in vitro and in silico study
Published in BMC chemistry (30-03-2024)“…Phytochemical investigation of Key lime ( Citrus aurantifolia L., F. Rutaceae) peels afforded six metabolites, known as methyl isolimonate acetate (1), limonin…”
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Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations
Published in Beni-Suef University journal of basic and applied sciences (01-12-2024)“…Background Solanum lycopersicum Linn. (Tomato, Family Solanaceae) is one of the fruits that are most consumed worldwide. The current research intends to…”
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Anti-Alzheimer Potential of a New (+)-Pinitol Glycoside Isolated from Tamarindus indica Pulp: In Vivo and In Silico Evaluations
Published in Metabolites (07-06-2023)“…Linn (tamarind, F. Leguminosae) is one of the most widely consumed edible fruits in the world. Phytochemical investigation of tamarind pulp -butanol fraction…”
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Nutraceutical Effect of Resveratrol on the Mammary Gland: Focusing on the NF-κb /Nrf2 Signaling Pathways
Published in Animals (Basel) (01-04-2023)“…The aim of this study is to evaluate the defensive role of resveratrol, which is antagonistic to the oxidative stress and inflammation that is prompted by LPS…”
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Abelmoschus eculentus Seed Extract Exhibits In Vitro and In Vivo Anti-Alzheimer's Potential Supported by Metabolomic and Computational Investigation
Published in Plants (Basel) (20-06-2023)“…Linn. (okra, F. Malvaceae) is a fruit widely consumed all over the world. In our study, the anti-Alzheimer's potential of was evaluated. An in vitro DPPH free…”
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Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-κB/NF-κB p65 signaling pathway: insights from in silico and in vivo investigations
Published in BMC complementary and alternative medicine (14-02-2024)“…Gastric ulcers represent a worldwide health problem, characterized by erosions that affect the mucous membrane of the stomach and may even reach the muscular…”
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Phosphoinositide 3-Kinase Inhibitors from Gladiolus segetum Ker-Gawl Corms Supported by Network Pharmacology
Published in Chemistry & biodiversity (29-10-2024)“…Gladiolus segetum Ker-Gawl corms total extract exhibited remarkable in vitro anti-proliferative effects against panel of cancer cell lines; including human…”
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Identification of Novel Genomic Variants in COVID-19 Patients Using Whole-Exome Sequencing: Exploring the Plausible Targets of Functional Genomics
Published in Biochemical genetics (18-11-2024)“…Covid-19 caused by SARS-CoV-2 virus has emerged as an immense burden and an unparalleled global health challenge in recorded human history. The clinical…”
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Unlocking the potential of edible Ulva sp. seaweeds: Metabolomic profiling, neuroprotective mechanisms, and implications for Parkinson's disease management
Published in Archiv der Pharmazie (Weinheim) (01-11-2024)“…Green seaweed (Ulva sp.) is frequently used as a food component and nutraceutical agent because of its high polysaccharide and natural fiber content in Asian…”
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