Search Results - "A‐Gonzalez, Noelia"

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity by Rauschmeier, René, Gustafsson, Charlotte, Reinhardt, Annika, A‐Gonzalez, Noelia, Tortola, Luigi, Cansever, Dilay, Subramanian, Sethuraman, Taneja, Reshma, Rossner, Moritz J, Sieweke, Michael H, Greter, Melanie, Månsson, Robert, Busslinger, Meinrad, Kreslavsky, Taras

“…Tissues in multicellular organisms are populated by resident macrophages, which perform both generic and tissue‐specific functions. The latter are induced by…”
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Innate immune cells as homeostatic regulators of the hematopoietic niche by Casanova-Acebes, María, A-González, Noelia, Weiss, Linnea A., Hidalgo, Andrés

“…Two cellular systems of paramount importance for mammalian physiology, the myeloid and the hematopoietic, have received a great deal of attention in the past…”
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Neutrophils instruct homeostatic and pathological states in naive tissues by Casanova-Acebes, Maria, Nicolás-Ávila, José A, Li, Jackson LiangYao, García-Silva, Susana, Balachander, Akhila, Rubio-Ponce, Andrea, Weiss, Linnea A, Adrover, José M, Burrows, Kyle, A-González, Noelia, Ballesteros, Ivan, Devi, Sapna, Quintana, Juan A, Crainiciuc, Georgiana, Leiva, Magdalena, Gunzer, Matthias, Weber, Christian, Nagasawa, Takashi, Soehnlein, Oliver, Merad, Miriam, Mortha, Arthur, Ng, Lai Guan, Peinado, Hector, Hidalgo, Andrés

“…Immune protection relies on the capacity of neutrophils to infiltrate challenged tissues. Naive tissues, in contrast, are believed to remain free of these…”
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Phagocytosis imprints heterogeneity in tissue-resident macrophages by A-Gonzalez, Noelia, Quintana, Juan A, García-Silva, Susana, Mazariegos, Marina, González de la Aleja, Arturo, Nicolás-Ávila, José A, Walter, Wencke, Adrover, Jose M, Crainiciuc, Georgiana, Kuchroo, Vijay K, Rothlin, Carla V, Peinado, Héctor, Castrillo, Antonio, Ricote, Mercedes, Hidalgo, Andrés

“…Tissue-resident macrophages display varying phenotypic and functional properties that are largely specified by their local environment. One of these functions,…”
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Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance by Casanova-Acebes, María, Pitaval, Christophe, Weiss, Linnea A., Nombela-Arrieta, César, Chèvre, Raphaël, A-González, Noelia, Kunisaki, Yuya, Zhang, Dachuan, van Rooijen, Nico, Silberstein, Leslie E., Weber, Christian, Nagasawa, Takashi, Frenette, Paul S., Castrillo, Antonio, Hidalgo, Andrés

“…Unique among leukocytes, neutrophils follow daily cycles of release from and migration back into the bone marrow, where they are eliminated. Because removal of…”
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Liver X receptors as regulators of macrophage inflammatory and metabolic pathways by A-González, Noelia, Castrillo, Antonio

“…The liver X receptors (LXRα and LXRβ) are members of the nuclear receptor family of transcription factors that play essential roles in the transcriptional…”
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Stroke induces disease-specific myeloid cells in the brain parenchyma and pia by Beuker, Carolin, Schafflick, David, Strecker, Jan-Kolja, Heming, Michael, Li, Xiaolin, Wolbert, Jolien, Schmidt-Pogoda, Antje, Thomas, Christian, Kuhlmann, Tanja, Aranda-Pardos, Irene, A-Gonzalez, Noelia, Kumar, Praveen Ashok, Werner, Yves, Kilic, Ertugrul, Hermann, Dirk M., Wiendl, Heinz, Stumm, Ralf, Meyer zu Hörste, Gerd, Minnerup, Jens

“…Inflammation triggers secondary brain damage after stroke. The meninges and other CNS border compartments serve as invasion sites for leukocyte influx into the…”
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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism by Crespo, María, Gonzalez-Teran, Barbara, Nikolic, Ivana, Mora, Alfonso, Folgueira, Cintia, Rodríguez, Elena, Leiva-Vega, Luis, Pintor-Chocano, Aránzazu, Fernández-Chacón, Macarena, Ruiz-Garrido, Irene, Cicuéndez, Beatriz, Tomás-Loba, Antonia, A-Gonzalez, Noelia, Caballero-Molano, Ainoa, Beiroa, Daniel, Hernández-Cosido, Lourdes, Torres, Jorge L, Kennedy, Norman J, Davis, Roger J, Benedito, Rui, Marcos, Miguel, Nogueiras, Ruben, Hidalgo, Andrés, Matesanz, Nuria, Leiva, Magdalena, Sabio, Guadalupe

“…Liver metabolism follows diurnal fluctuations through the modulation of molecular clock genes. Disruption of this molecular clock can result in metabolic…”
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Coordinate regulation of neutrophil homeostasis by liver X receptors in mice by Hong, Cynthia, Kidani, Yoko, A-Gonzalez, Noelia, Phung, Tram, Ito, Ayaka, Rong, Xin, Ericson, Katrin, Mikkola, Hanna, Beaven, Simon W, Miller, Lloyd S, Shao, Wen-Hai, Cohen, Philip L, Castrillo, Antonio, Tontonoz, Peter, Bensinger, Steven J

“…The most abundant immune cell type is the neutrophil, a key first responder after pathogen invasion. Neutrophil numbers in the periphery are tightly regulated…”
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Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow by Devi, Sapna, Wang, Yilin, Chew, Weng Keong, Lima, Ronald, A-González, Noelia, Mattar, Citra N Z, Chong, Shu Zhen, Schlitzer, Andreas, Bakocevic, Nadja, Chew, Samantha, Keeble, Jo L, Goh, Chi Ching, Li, Jackson L Y, Evrard, Maximilien, Malleret, Benoit, Larbi, Anis, Renia, Laurent, Haniffa, Muzlifah, Tan, Suet Mien, Chan, Jerry K Y, Balabanian, Karl, Nagasawa, Takashi, Bachelerie, Françoise, Hidalgo, Andrés, Ginhoux, Florent, Kubes, Paul, Ng, Lai Guan

“…Blood neutrophil homeostasis is essential for successful host defense against invading pathogens. Circulating neutrophil counts are positively regulated by…”
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Origin and specialization of splenic macrophages by A-Gonzalez, Noelia, Castrillo, Antonio

“…•The Spleen is the largest secondary lymphoid organ and the largest blood filter.•The Spleen is crucial for the generation of immune responses to blood-borne…”
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Emerging roles of infiltrating granulocytes and monocytes in homeostasis by Groeneweg, Linda, Hidalgo, Andres, A-Gonzalez, Noelia

“…The infiltration of naïve tissues by myeloid cells has been long related to their clearance and the physiological cell turnover, however, increasing evidence…”
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Lipid metabolism as a mechanism of immunomodulation in macrophages: the role of liver X receptors by Leussink, Sophia, Aranda-Pardos, Irene, A-Gonzalez, Noelia

“…Macrophages are immune myeloid cells with an extreme ability to modulate their phenotype in response to insults and/or pathogens. The immunomodulatory capacity…”
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Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and Resolution by Shahneh, Fatemeh, Christian Probst, Hans, Wiesmann, Sabine C., A-Gonzalez, Noelia, Ruf, Wolfram, Steinbrink, Kerstin, Raker, Verena K., Becker, Christian

“…Monocytes are thought to be involved in venous thrombosis but the role of individual monocyte subpopulations on thrombus formation, clot inflammation, and…”
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Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR by A-Gonzalez, Noelia, Bensinger, Steven J., Hong, Cynthia, Beceiro, Susana, Bradley, Michelle N., Zelcer, Noam, Deniz, Jose, Ramirez, Cristina, Díaz, Mercedes, Gallardo, German, Ruiz de Galarreta, Carlos, Salazar, Jon, Lopez, Felix, Edwards, Peter, Parks, John, Andujar, Miguel, Tontonoz, Peter, Castrillo, Antonio

“…Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and…”
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Delayed alveolar clearance of nanoparticles through control of coating composition and interaction with lung surfactant protein A by Carregal-Romero, Susana, Groult, Hugo, Cañadas, Olga, A-Gonzalez, Noelia, Lechuga-Vieco, Ana Victoria, García-Fojeda, Belén, Herranz, Fernando, Pellico, Juan, Hidalgo, Andrés, Casals, Cristina, Ruiz-Cabello, Jesús

“…The coating composition of nanomedicines is one of the main features in determining the medicines' fate, clearance, and immunoresponse in the body. To…”
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The nuclear receptor LXRα controls the functional specialization of splenic macrophages by A-Gonzalez, Noelia, Guillen, Jose A, Gallardo, Germán, Diaz, Mercedes, de la Rosa, Juan V, Hernandez, Irene H, Casanova-Acebes, Maria, Lopez, Felix, Tabraue, Carlos, Beceiro, Susana, Hong, Cynthia, Lara, Pedro C, Andujar, Miguel, Arai, Satoko, Miyazaki, Toru, Li, Senlin, Corbi, Angel L, Tontonoz, Peter, Hidalgo, Andres, Castrillo, Antonio

“…Liver X receptors (LXRs) are transcription factors that respond to sterols. Castrillo and colleagues identify a unique requirement for LXRα in the development…”
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Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages by Liebold, Imke, Al Jawazneh, Amirah, Casar, Christian, Lanzloth, Clarissa, Leyk, Stephanie, Hamley, Madeleine, Wong, Milagros N, Kylies, Dominik, Gräfe, Stefanie K, Edenhofer, Ilka, Aranda-Pardos, Irene, Kriwet, Marie, Haas, Helmuth, Krause, Jenny, Hadjilaou, Alexandros, Schromm, Andra B, Richardt, Ulricke, Eggert, Petra, Tappe, Dennis, Weidemann, Sören A, Ghosh, Sourav, Krebs, Christian F, A-Gonzalez, Noelia, Worthmann, Anna, Lohse, Ansgar W, Huber, Samuel, Rothlin, Carla V, Puelles, Victor G, Jacobs, Thomas, Gagliani, Nicola, Bosurgi, Lidia

“…Macrophages are functionally heterogeneous cells essential for apoptotic cell clearance. Apoptotic cells are defined by homogeneous characteristics, ignoring…”
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Liver X Receptor Nuclear Receptors Are Transcriptional Regulators of Dendritic Cell Chemotaxis by Beceiro, Susana, Pap, Attila, Czimmerer, Zsolt, Sallam, Tamer, Guillén, Jose A., Gallardo, Germán, Hong, Cynthia, A-Gonzalez, Noelia, Tabraue, Carlos, Diaz, Mercedes, Lopez, Felix, Matalonga, Jonathan, Valledor, Annabel F., Dominguez, Pilar, Ardavin, Carlos, Delgado-Martin, Cristina, Partida-Sanchez, Santiago, Rodriguez-Fernandez, Jose Luis, Nagy, Laszlo, Tontonoz, Peter, Castrillo, Antonio

“…The liver X receptors (LXRs) are ligand-activated nuclear receptors with established roles in the maintenance of lipid homeostasis in multiple tissues. LXRs…”
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Relevance of angiotensin-(1-7) and its receptor Mas in pneumonia caused by influenza virus and post-influenza pneumococcal infection by Melo, Eliza M., Del Sarto, Juliana, Vago, Juliana P., Tavares, Luciana P., Rago, Flávia, Gonçalves, Ana Paula F., Machado, Marina G., Aranda-Pardos, Irene, Valiate, Bruno V.S., Cassali, Geovanni D., Pinho, Vanessa, Sousa, Lirlândia P., A-Gonzalez, Noelia, Campagnole-Santos, Maria José, Bader, Michael, Santos, Robson A.S., Machado, Alexandre V., Ludwig, Stephan, Teixeira, Mauro M.

“…Graphical Abstract: Schematic representation of the role of Angiotensin-(1–7) [Ang-(1–7)] treatment after Influenza A virus infection. The main effects of…”
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