Search Results - "Aćimović Jelena M."
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Protein modifications screening of raw and thermally treated meat gastrointestinal digesta
Published in Journal of functional foods (01-02-2024)“…[Display omitted] •Protein of meat and their digesta were screened for modifications (PMs) in Westen blotting (WB)•Lysine methylation and oxidative…”
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The interplay between copper(II), human serum albumin, fatty acids, and carbonylating agent interferes with Cys 34 thiol reactivity and copper binding
Published in Journal of biological inorganic chemistry (01-02-2019)“…Cys34 thiol group of human serum albumin (HSA) represents major plasma antioxidant. Its reactivity is influenced by multiple factors. The influence of fatty…”
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Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal
Published in Chemico-biological interactions (05-12-2014)“…[Display omitted] •Free fatty acids binding amplify the reactivity of HSA Cys34 thiol group.•HSA free thiol group reaction kinetic changes with different fatty…”
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The influence of fatty acids on determination of human serum albumin thiol group
Published in Analytical biochemistry (01-03-2014)“…During investigation of the changes of the Cys34 thiol group of human serum albumin (HSA) (isolated by affinity chromatography with Cibacron Blue (CB)) in…”
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Quantification of total content of non-esterified fatty acids bound to human serum albumin
Published in Journal of pharmaceutical and biomedical analysis (10-09-2016)“…[Display omitted] •A method for cheap and fast quantification of total FAs bound to the HSA was defined.•Uses specific extraction conditions, utilizing TLC…”
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Improving the reliability of human serum albumin-thiol group determination
Published in Analytical biochemistry (01-08-2013)“…The thiol (Cys34) content of human serum albumin (HSA-SH) decreases during oxidative and carbonyl stress and, therefore, could represent a useful parameter in…”
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Binding of enterolactone and enterodiol to human serum albumin: increase of cysteine-34 thiol group reactivity
Published in Food & function (01-02-2016)“…The interaction of polyphenolic molecules with human serum albumin (HSA) could lead to changes in the reactivity of the HSA Cys34 thiol group (HSA-SH). The…”
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Method for monitoring of the protein amino group changes during carbonylation
Published in Clinical biochemistry (01-08-2011)“…Carbonylation of the protein amino, guanidino and thiol groups is one of the important causes of vascular complications in diabetes. We developed a simple…”
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HSA carbonylation with methylglyoxal and the binding/release of copper(ii) ions
Published in Metallomics (01-10-2015)“…The potential of carbonylation with methylglyoxal to alter HSA's binding affinity for copper( ii ) ions and its influence on the release of copper( ii ) ions…”
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Monitoring of the human serum albumin carbonylation level through determination of guanidino group content
Published in Analytical biochemistry (15-02-2013)“…Carbonylation of the protein amino, guanidine, and thiol groups with α-oxoaldehydes (which are produced in higher quantities in diabetes, uremia, oxidative…”
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Influence of the microenvironment of thiol groups in low molecular mass thiols and serum albumin on the reaction with methylglyoxal
Published in Chemico-biological interactions (06-10-2010)“…[Display omitted] ▶ Microenvironment of SH has effect on its reactivity with MG and product yield. ▶ Substances with α-amino-β-mercapto-ethan pharmacophore are…”
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The efficiency of compounds with α-amino-β-mercapto-ethane group in protection of human serum albumin carbonylation and cross-linking with methylglyoxal
Published in Molecular bioSystems (01-01-2014)“…α-Oxoaldehydes, which are produced in higher quantities in diabetes, uremia, oxidative stress, inflammation and aging, react with the amino, guanidine and…”
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The role of the thiol group in protein modification with methylglyoxal
Published in Journal of the Serbian Chemical Society (01-01-2009)“…Methylglyoxal is a highly reactive α-oxoaldehyde with elevated production in hyperglycemia. It reacts with nucleophilic Lys and Arg side-chains and N-terminal…”
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Influence of pigments and pH of urine on the determination of N-acetyl-β-D-glucosaminidase activity with 2-methoxy-4-(2′-nitrovinyl)-phenyl-N-acetyl-β-D-glucosaminide
Published in Journal of clinical laboratory analysis (2005)“…The influence of urinary pigments and urine pH on the spectrophotometric determination of N‐acetyl‐β‐D‐glucosaminidase (NAG; EC 3.2.1.30) activity with…”
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The possibility of determining N-acetyl-β- d-glucosaminidase isoenzymes under alkaline conditions
Published in Clinical biochemistry (01-04-2005)“…To have a reliable diagnostic test, the influence of urine pH on the determination of the total activity of N-acetyl-β- d-glucosaminidase (NAG) and NAG…”
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How the sialylation level of serum N-acetyl-β-D-glucosaminidase a form in type 1 diabetes mellitus influences its activity?
Published in Journal of the Serbian Chemical Society (01-01-2014)“…It has been verified that serum N-acetyl-β-D-glucosaminidase (NAG) activity is elevated in diabetes, but there are no reports about changes of the sialic acid…”
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The role of the thiol group in protein modification with methylglyoxal
Published in Journal of the Serbian Chemical Society (01-01-2009)“…Methylglyoxal is a highly reactive α-oxoaldehyde with elevated production in hyperglycemia. It reacts with nucleophilic Lys and Arg side-chains and N-terminal…”
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Modifikacija -Sh Grupe Proteina α- Dikarbonilnim Jedinjenjima: Identifikacija Proizvoda, Mogućnosti Određivanja i Primene u Kliničkoj Praksi
Published 01-01-2012“…α-Dikarbonilna jedinjenja su veoma reaktivna, reaguju sa nukleofilnim grupama bocnih ostataka Lys i Arg, N-terminalnom amino-grupom i tiol-grupom ostatka Cys…”
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Dissertation