Search Results - "A, Spatz"

The validity of circulating microRNAs in oncology: Five years of challenges and contradictions by Jarry, J., Schadendorf, D., Greenwood, C., Spatz, A., van Kempen, L.C.

“…MicroRNAs (miRNAs) in circulation have received an increasing amount of interest as potential minimal invasive diagnostic tools in oncology. Several…”
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Cytology cell blocks are suitable for immunohistochemical testing for PD-L1 in lung cancer by Wang, H., Agulnik, J., Kasymjanova, G., Wang, A., Jiménez, P., Cohen, V., Small, D., Pepe, C., Sakr, L., Fiset, P.O., Auger, M., Camilleri-Broet, S., Alam El Din, M., Chong, G., van Kempen, L., Spatz, A.

“…PD-L1 immunohistochemistry (IHC) testing is usually carried out on tissue blocks from core needle biopsy or surgical resections. In this study, we assessed the…”
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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice by Klein, Florian, Halper-Stromberg, Ariel, Horwitz, Joshua A., Gruell, Henning, Scheid, Johannes F., Bournazos, Stylianos, Mouquet, Hugo, Spatz, Linda A., Diskin, Ron, Abadir, Alexander, Zang, Trinity, Dorner, Marcus, Billerbeck, Eva, Labitt, Rachael N., Gaebler, Christian, Marcovecchio, Paola M., Incesu, Reha-Baris, Eisenreich, Thomas R., Bieniasz, Paul D., Seaman, Michael S., Bjorkman, Pamela J., Ravetch, Jeffrey V., Ploss, Alexander, Nussenzweig, Michel C.

“…Passive immunotherapy with a combination of neutralizing monoclonal antibodies is shown to be effective in suppressing HIV replication in a humanized mouse…”
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Editorial: Pathogens, Pathobionts, and Autoimmunity by Spatz, Linda A, Silverman, Gregg J, James, Judith A

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How iMALDI can improve clinical diagnostics by Popp, R, Basik, M, Spatz, A, Batist, G, Zahedi, R P, Borchers, C H

“…Protein mass spectrometry (MS) is an indispensable tool to detect molecular signatures that can be associated with cellular dysregulation and disease. Despite…”
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High expression of DNA repair pathways is associated with metastasis in melanoma patients by Kauffmann, A, Rosselli, F, Lazar, V, Winnepenninckx, V, Mansuet-Lupo, A, Dessen, P, van den Oord, J J, Spatz, A, Sarasin, A

“…We have identified a gene-profile signature for human primary malignant melanoma associated with metastasis to distant sites and poor prognosis. We analyse the…”
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The Janus face of dendritic cells in cancer by Chaput, N, Conforti, R, Viaud, S, Spatz, A, Zitvogel, L

“…On the basis of experimental models and some human data, we can assume that tumor outgrowth results from the balance between immunosurveillance (the extrinsic…”
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Poor biosecurity could lead to disease outbreaks in animal populations by Gray, Matthew J, Spatz, Jennifer A, Carter, E Davis, Yarber, Christian M, Wilkes, Rebecca P, Miller, Debra L

“…Human-mediated disease outbreaks due to poor biosecurity practices when processing animals in wild populations have been suspected. We tested whether not…”
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Conservation risk of Batrachochytrium salamandrivorans to endemic lungless salamanders by Carter, Edward Davis, Miller, Debra L., Peterson, Anna C., Sutton, William B., Cusaac, Joseph Patrick W., Spatz, Jennifer A., Rollins‐Smith, Louise, Reinert, Laura, Bohanon, Markese, Williams, Lori A., Upchurch, Andrea, Gray, Matthew J.

“…The emerging fungal pathogen, Batrachochytrium salamandrivorans (Bsal), is a significant conservation threat to salamander biodiversity in Europe, although its…”
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The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma by Wang, H., Agulnik, J., Kasymjanova, G., Fiset, P.O., Camilleri-Broet, S., Redpath, M., Cohen, V., Small, D., Pepe, C., Sakr, L., Spatz, A.

“…•The PD-L1 expression similar in NSCLC from distant metastatic sites.•Samples from any accessible distant metastatic sites can be used for PD-L1 testing.•The…”
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Decision analysis of medical and surgical treatments for trigeminal neuralgia: How patient evaluations of benefits and risks affect the utility of treatment decisions by Spatz, A.L., Zakrzewska, J.M., Kay, E.J.

“…Trigeminal neuralgia (TN) is a rare form of neuropathic facial pain characterised by severe, paroxysmal pains in the face. Little is known about the decision…”
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EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors? by Paliga, A, Onerheim, R, Gologan, A, Chong, G, Spatz, A, Niazi, T, Garant, A, Macheto, D, Alcindor, T, Vuong, T

“…Background: There is a growing appreciation for radio-sensitiser use in multi-modal cancer treatment models. Squamous cell anal carcinoma (SCAC) is a rare…”
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A Canadian guideline on the use of next-generation sequencing in oncology by Yip, S, Christofides, A, Banerji, S, Downes, M R, Izevbaye, I, Lo, B, MacMillan, A, McCuaig, J, Stockley, T, Yousef, G M, Spatz, A

“…Rapid advancements in next-generation sequencing (ngs) technology have created an unprecedented opportunity to decipher the molecular profile of tumours to…”
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Biomarkers in melanoma by Gogas, H., Eggermont, A. M. M., Hauschild, A., Hersey, P., Mohr, P., Schadendorf, D., Spatz, A., Dummer, R.

“…Biomarkers are tumour- or host-related factors that correlate with tumour biological behaviour and patient prognosis. High-throughput analytical techniques—DNA…”
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Erratum to “The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma” [Lung Cancer 132 (June) (2019) 36–38] by Wang, H., Agulnik, J., Kasymjanova, G., Fiset, P.O., Camilleri-Broet, S., Redpath, M., Cohen, V., Small, D., Pepe, C., Sakr, L., Spatz, A.

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Evidence-based best practices for EGFR T790M testing in lung cancer in Canada by Stockley, T, Souza, C A, Cheema, P K, Melosky, B, Kamel-Reid, S, Tsao, M S, Spatz, A, Karsan, A

“…Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors (tkis) are recommended as first-line systemic therapy for patients with non-small-cell lung…”
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Can Clinical Criteria Estimate Pathological Complete Response in Rectal Cancer Treated With Neoadjuvant High Dose Rate Brachytherapy? by Garant, A, Niazi, T.M, Gologan, A, Spatz, A, Letellier, F, Faria, J, Morin, N, Vasilevsky, C.A, Desgroseilliers, S, Vuong, T

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EP-1291: Can mucosal criteria estimate response in rectal cancer treated with neoadjuvant chemoradiotherapy? by Garant, A, Niazi, T, Gologan, A, Spatz, A, Faria, J, Morin, N, Vasilevsky, C, Boutros, M, Vuong, T

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The role of molecular pathology in non-small-cell lung carcinoma-now and in the future by Brandao, G D A, Brega, E F, Spatz, A

“…In recent years, better understanding of the molecular biology of non-small-cell lung carcinoma (nsclc) has led to a revolution in the work-up of these…”
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Prostate cancer microenvironment: Its structure, functions and therapeutic applications by Lorion, R, Bladou, F, Spatz, A, van Kempen, L, Irani, J

“…In the field of prostate cancer there is a growing tendency for more and more studies to emphasise the predominant role of the zone situated between the tumour…”
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