Search Results - "A, Guise"
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1
Breast Cancer Bone Metastases: It’s All about the Neighborhood
Published in Cell (29-08-2013)“…In order to establish themselves in distal sites, metastatic cancer cells need to acquire organ-specific traits. Zhang et al. provide evidence in breast cancer…”
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2
Molecular Mechanisms of Bone Metastasis and Associated Muscle Weakness
Published in Clinical cancer research (15-06-2014)“…Bone is a preferred site for breast cancer metastasis and leads to pathologic bone loss due to increased osteoclast-induced bone resorption. The homing of…”
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3
Alkaline phosphatase in metastatic castration-resistant prostate cancer: reassessment of an older biomarker
Published in Future oncology (London, England) (01-10-2018)“…Since most patients with metastatic castration-resistant prostate cancer (mCRPC) have bone metastases, it is important to understand the potential impact of…”
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4
The bone-muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health
Published in Breast cancer research : BCR (23-11-2022)“…Breast cancer and its therapies frequently result in significant musculoskeletal morbidity. Skeletal complications include bone metastases, pain, bone loss,…”
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5
Toward Automated 3D Spine Reconstruction from Biplanar Radiographs Using CNN for Statistical Spine Model Fitting
Published in IEEE transactions on medical imaging (01-12-2019)“…To date, 3D spine reconstruction from biplanar radiographs involves intensive user supervision and semi-automated methods that are time-consuming and not…”
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6
Radium-223 mechanism of action: implications for use in treatment combinations
Published in Nature reviews. Urology (01-12-2019)“…The targeted alpha therapy radium-223 ( 223 Ra) can prolong survival in men with castration-resistant prostate cancer (CRPC) who have symptomatic bone…”
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7
Haemorrhagic complications following cataract and vitreoretinal surgery with sub-Tenon's block in patients receiving non-vitamin K oral anticoagulant agents: A prospective audit
Published in Anaesthesia and intensive care (01-07-2022)“…There is a lack of data to support either continuation or interruption of non-vitamin K oral anticoagulants for cataract and vitreoretinal surgery. A…”
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8
Antitumor effects of bisphosphonates: Promising preclinical evidence
Published in Cancer treatment reviews (2008)“…Summary The majority of patients with advanced cancer will ultimately develop bone metastases. The bone microenvironment provides fertile soil for a cycle of…”
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9
The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone
Published in Cancer cell (08-06-2015)“…Transforming growth factor-β (TGF-β) regulates the expression of genes supporting breast cancer cells in bone, but little is known about prostate cancer bone…”
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10
Breast cancer metastasis to bone : Mechanisms of osteolysis and implications for therapy
Published in Journal of mammary gland biology and neoplasia (01-04-2005)“…The most common skeletal complication of breast cancer is osteolytic bone metastasis. Bone metastases are present in 80% of patients with advanced disease and…”
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11
Osteocyte CIITA aggravates osteolytic bone lesions in myeloma
Published in Nature communications (27-06-2022)“…Osteolytic destruction is a hallmark of multiple myeloma, resulting from activation of osteoclast-mediated bone resorption and reduction of osteoblast-mediated…”
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12
The Role of TGF-β in Bone Metastases
Published in Biomolecules (Basel, Switzerland) (06-11-2021)“…Complications associated with advanced cancer are a major clinical challenge and, if associated with bone metastases, worsen the prognosis and compromise the…”
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13
Bone Loss and Fracture Risk Associated with Cancer Therapy
Published in The oncologist (Dayton, Ohio) (01-11-2006)“…Learning Objectives After completing this course, the reader will be able to: Identify cancer therapies associated with bone loss. Explain the unique aspects…”
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14
Molecular Biology of Bone Metastasis
Published in Molecular cancer therapeutics (01-10-2007)“…Metastasis is a final stage of tumor progression. Breast and prostate cancer cells preferentially metastasize to bone, wherein they cause incurable osteolytic…”
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15
Acute bilateral parotid swelling upon laryngeal mask airway insertion: A case report
Published in Anaesthesia and intensive care (01-01-2023)“…We describe a case of bilateral parotid swelling developing shortly after laryngeal mask airway insertion. Spontaneous resolution occurred within 12 h…”
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16
Liver segmentation: indications, techniques and future directions
Published in Insights into imaging (01-08-2017)“…Objectives Liver volumetry has emerged as an important tool in clinical practice. Liver volume is assessed primarily via organ segmentation of computed…”
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17
Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone
Published in Endocrine-related cancer (01-09-2005)“…Calcium homeostasis is a tightly regulated process involving the co-ordinated efforts of the skeleton, kidney, parathyroid glands and intestine. Neoplasms can…”
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18
Soft tissue artifact compensation in knee kinematics by multi-body optimization: Performance of subject-specific knee joint models
Published in Journal of biomechanics (05-11-2015)“…Abstract Soft tissue artifact (STA) distort marker-based knee kinematics measures and make them difficult to use in clinical practice. None of the current…”
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19
A multigenic program mediating breast cancer metastasis to bone
Published in Cancer cell (01-06-2003)“…We investigated the molecular basis for osteolytic bone metastasis by selecting human breast cancer cell line subpopulations with elevated metastatic activity…”
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20
Basic Mechanisms Responsible for Osteolytic and Osteoblastic Bone Metastases
Published in Clinical cancer research (15-10-2006)“…Certain solid tumors metastasize to bone and cause osteolysis and abnormal new bone formation. The respective phenotypes of dysregulated bone destruction and…”
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