Search Results - "高野, 晋吾"
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Prognostic factors in glioblastoma multiforme patients receiving high-dose particle radiotherapy or conventional radiotherapy
Published in British journal of radiology (01-12-2011)“…The aim of this study was to evaluate the influence of prognostic factors related to patient selection on survival outcomes. Survival outcomes were…”
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重複中大脳動脈起始部の脳動脈瘤の1例
Published in Neurologia medico-chirurgica (1988)“…従来, 中大脳動脈奇形として重複中大脳動脈, 副中大脳動脈, 窓形成などが知られており, 1962年のCromptonら3)の報告以来, 多数の報告例がみられる. しかし, 重複中大脳動脈に脳動脈瘤が合併した症例は文献上24例にすぎず, さらに重複中大脳動脈の起始部に脳動脈瘤が発生した症例はわずか6例のみである…”
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Cloverleaf Skull Syndromeの2例
Published in Neurologia medico-chirurgica (1989)“…1960年Holtermuller and Wiedemann9)はchondrodystrophic hydrocephalusと呼ばれていた症例を総括して“Kleeblattschadel syndrome”と記載した. 彼らはその特徴として, (1)trilocular configuration of the…”
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脳腫瘍に対する陽子線治療
Published in Neurologia medico-chirurgica (1986)“…悪性脳腫瘍に対して手術後, 集学的療法として放射線治療や化学・免疫療法を用いることは現在ではごく一般的となっている. 術後の放射線治療は1960年代に普及した高エネルギーX線治療法により向上したが, それから20数年を経た現在, 同調期放射線治療法や種々の化学療法を併用しても,…”
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脳腫瘍に対するargon laserと光増感剤併用治療に関する研究
Published in Neurologia medico-chirurgica (1987)“…悪性腫瘍に対する治療法は種々, 試みられているが, いずれの方法もいまだcurable therapeutic methodとは言えない. 可視域レーザーと光増感剤を併用した光化学療法(photodynamic therapy, 以下PDT)の利点は, (1)手術時に直視下で操作が行えること,…”
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Clinical significance of disease‐specific MYD88 mutations in circulating DNA in primary central nervous system lymphoma
Published in Cancer science (01-01-2018)“…Recent sequencing studies demonstrated the MYD88 L265P mutation in more than 70% of primary central nervous system lymphomas (PCNSL), and the clinical…”
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Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10
Published in International journal of oncology (01-11-2014)“…Interferon-β (IFN-β) has been used clinically for malignant glioma growth inhibition. Recently IFN-β is re-evaluated for its sensitization mechanism to the…”
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Recent Status of Phase I Clinical Trials for Brain Tumors: A Regulatory Science Study of Exploratory Efficacy Endpoints
Published in Therapeutic innovation & regulatory science (01-07-2024)“…Appropriate exploratory efficacy data from Phase I trials are vital for subsequent phases. Owing to the uniqueness of brain tumors (BTs), use of different…”
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Genetic evidence implies that primary and relapsed tumors arise from common precursor cells in primary central nervous system lymphoma
Published in Cancer science (01-01-2019)“…Primary central nervous system lymphoma (PCNSL) is a rare subtype of lymphoma that arises within the brain or the eyes. PCNSL recurs within the central nervous…”
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Prognostic analysis of patients who underwent gross total resection of newly diagnosed glioblastoma
Published in Journal of clinical neuroscience (01-04-2018)“…•Tumor involvement of the SVZ was associated with poor survival of GBM patients who underwent GTR.•Tumor involvement of the SVZ was significantly associated…”
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Efficacy of bevacizumab therapy in recurrent malignant gliomas in relation to the prior recurrence pattern or tumor location
Published in Journal of clinical neuroscience (01-06-2017)“…Highlights • Patients with leptomeningeal dissemination experience minimal benefit from bevacizumab. • The primary location of tumor was not associated with…”
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Metronomic treatment of malignant glioma xenografts with irinotecan (CPT-11) inhibits angiogenesis and tumor growth
Published in Journal of neuro-oncology (01-09-2010)“…Irinotecan (CPT-11) has shown emerging promise in the treatment of malignant gliomas. It is believed the mechanism of action of irinotecan is to sensitize…”
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Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma
Published in Neurologia medico-chirurgica (2018)“…A 43-year-old man was operated on for right frontal oligoastrocytoma. 14 years after the surgery, magnetic resonance imaging and positron emission tomography…”
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IDH-wildtype infiltrative low-grade glial tumor with nodule-like enhancement pattern
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-12-2018)“…The authors describe a usual case of infiltrative low-grade glial neoplasm with a marked enhanced area which is difficult to diagnose. A 42-year-old man had…”
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Direct comparison of thallium-201 and technetium-99m MIBI SPECT of a glioma by receiver operating characteristic analysis
Published in Journal of clinical neuroscience (01-02-2009)“…Abstract The diagnostic value of single photon-emission computed tomography (SPECT) has been assessed using arbitrarily determined sensitivity and specificity…”
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Angiogenesis and antiangiogenic therapy for malignant gliomas
Published in Brain tumor pathology (01-06-2004)“…Angiogenesis is crucial to the growth of malignant gliomas. Therefore, antiangiogenic therapy represents a new, promising therapeutic modality for malignant…”
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Facial Spasm and Paroxysmal Tinnitus Associated with an Arachnoid Cyst of the Cerebellopontine Angle —Case Report
Published in Neurologia medico-chirurgica (1998)“…A 59-year-old female presented with a 3-year history of hemifacial spasm and paroxysmal tinnitus associated with an arachnoid cyst of the cerebellopontine…”
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Oculomotor palsy treated by microvascular decompression
Published in Surgical neurology (01-08-2008)“…Abstract Background Oculomotor palsy is well known to be due to diabetes mellitus, or aneurysmal compression, or cavernous sinus lesion. Only few reports…”
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