Search Results - "荒井, 博敏"
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新規抗潰瘍剤(T-593)の開発研究.ラニチジンのN-2-(2-ヒドロキシ-2-フェニル)-エチル-N"-(メタンスルホニル)グアニジン類縁体の合成と抗潰瘍活性
Published in YAKUGAKU ZASSHI (01-03-1998)Get full text
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Effect of T-593 on gastric bleeding and lesions induced by indomethacin and water-immersion stress in rats: improving effect of T-593 on reduced gastric mucosal blood flow in rats
Published in Nihon yakurigaku zasshi (01-08-1998)“…The effect of T-593, a novel antiulcer agent, was investigated with respect to gastric bleeding and lesions induced by indomethacin (3 mg/kg, s.c.) and water…”
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Characteristics of T-593, a novel antiulcer agent, and each of its enantiomers on pharmacodynamics
Published in Nihon yakurigaku zasshi (1998)“…T-593 consists of two optical isomers, (-)-S and (+)-R. Our previous report showed that T-593 has biphasic effects, that is a long-lasting antisecretory action…”
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産婦人科領域におけるCefoperazoneの基礎的・臨床的研究
Published in CHEMOTHERAPY (25-01-1981)“…Cefoperazone (CPZ) の産婦人科領域での基礎的研究として下記の実験を行った。 1) CPZの子宮各組織内濃度を測定し, コンピューターによってsimulation curveを求めた。投与法は静注, 筋注, 点滴で投与量は2gである。対照薬としてcefazolin (CEZ)…”
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