Search Results - "森田, 智視"
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急性期虚血性脳卒中患者における90日後の重篤な転帰の予測因子
Published in 脳卒中 (2023)“…【背景および目的】適切な治療を行っても,重篤な転帰をたどる脳卒中患者がいる.本研究の目的は,入院時の情報から虚血性脳卒中患者の重篤な転帰を予測することである.【方法】5年9カ月間に入院した発症7日以内の脳梗塞,または一過性脳虚血発作連続例の前向き追跡調査データを用い,入院時情報(年齢,性別,発症前mRS,…”
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CPD6-3. Proximal Landing zone毎に分けた弓部疾患に対するステントグラフト内挿術成績と全弓部置換術成績の比較
Published in General Thoracic and Cardiovascular Surgery (2023)Get full text
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急性期虚血性脳卒中患者における90日後の重篤な転帰の予測因子
Published in 脳卒中 (2023)“…【背景および目的】適切な治療を行っても,重篤な転帰をたどる脳卒中患者がいる.本研究の目的は,入院時の情報から虚血性脳卒中患者の重篤な転帰を予測することである.【方法】5年9カ月間に入院した発症7日以内の脳梗塞,または一過性脳虚血発作連続例の前向き追跡調査データを用い,入院時情報(年齢,性別,発症前mRS,…”
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Real world treatment and outcomes in EGFR mutation-positive non-small cell lung cancer: Long-term follow-up of a large patient cohort
Published in Lung cancer (Amsterdam, Netherlands) (01-03-2018)“…•We conducted a real-world survival analysis of EGFR mutation-positive NSCLC.•This study provides long-term follow-up data on a large patient group.•Patients…”
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S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer (TRICOLORE): a randomized, open-label, phase III, noninferiority trial
Published in Annals of oncology (01-03-2018)“…Combination therapy with oral fluoropyrimidine and irinotecan has not yet been established as first-line treatment of metastatic colorectal cancer (mCRC). We…”
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Monitoring EGFR T790M with plasma DNA from lung cancer patients in a prospective observational study
Published in Cancer science (01-02-2016)“…Use of plasma DNA to detect mutations has spread widely as a form of liquid biopsy. EGFR T790M has been observed in half of lung cancer patients who have…”
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Final 3-year Results of the Dasatinib Discontinuation Trial in Patients With Chronic Myeloid Leukemia Who Received Dasatinib as a Second-line Treatment
Published in Clinical lymphoma, myeloma and leukemia (01-05-2018)“…We describe the results of a prospective trial of the discontinuation of second-line dasatinib treatment in chronic myeloid leukemia patients who maintained a…”
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Multi-institutional phase II study on the safety and efficacy of dynamic tumor tracking-stereotactic body radiotherapy for lung tumors
Published in Radiotherapy and oncology (01-07-2022)“…•Multi-institutional phase II study of DTT-SBRT was conducted for lung tumors.•Forty-eight patients with lung tumors presenting with respiratory motion were…”
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Genomic and transcriptomic profiling of pre- and postneoadjuvant chemotherapy triple negative breast cancer tumors
Published in Cancer science (07-10-2024)“…Our understanding of neoadjuvant treatment with microtubule inhibitors (MTIs) for triple negative breast cancer (TNBC) remains limited. To advance our…”
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Dasatinib cessation after deep molecular response exceeding 2 years and natural killer cell transition during dasatinib consolidation
Published in Cancer science (01-01-2018)“…Tyrosine kinase inhibitors (TKI) improve the prognosis of patients with chronic myelogenous leukemia (CML) by inducing substantial deep molecular responses…”
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Phase Ib/II study of nivolumab combined with palliative radiation therapy for bone metastasis in patients with HER2-negative metastatic breast cancer
Published in Scientific reports (27-12-2022)“…Radiation therapy (RT) can enhance the abscopal effect of immune checkpoint blockade. This phase I/II study investigated the efficacy and safety of nivolumab…”
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Biomarker-based Bayesian randomized phase II clinical trial design to identify a sensitive patient subpopulation
Published in Statistics in medicine (15-10-2014)“…The benefits and challenges of incorporating biomarkers into the development of anticancer agents have been increasingly discussed. In many cases, a sensitive…”
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Protein C activity as a potential prognostic factor for nursing home-acquired pneumonia
Published in PloS one (12-10-2022)“…Introduction Despite the poor prognosis for nursing home acquired pneumonia (NHAP), a useful prognostic factor is lacking. We evaluated protein C (PC) activity…”
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Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial
Published in PloS one (13-02-2020)“…Kyoto University Substance (KUS) 121, an ATPase inhibitor of valosin-containing protein, is a novel neuroprotectant. We tested the safety and effectiveness of…”
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Impaired CD4 + T cell response in older adults is associated with reduced immunogenicity and reactogenicity of mRNA COVID-19 vaccination
Published in Nature aging (01-01-2023)“…Whether age-associated defects in T cells impact the immunogenicity and reactogenicity of mRNA vaccines remains unclear. Using a vaccinated cohort (n = 216),…”
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Intake frequency of vegetables or seafoods negatively correlates with disease activity of rheumatoid arthritis
Published in PloS one (13-02-2020)“…To clarify the relationship between dietary habit and disease activity of rheumatoid arthritis (RA). This study enrolled RA patients who met the ACR/EULAR 2010…”
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Oral Food Intake Versus Fasting on Postoperative Pancreatic Fistula After Distal Pancreatectomy: A Multi-Institutional Randomized Controlled Trial
Published in Medicine (Baltimore) (01-12-2015)“…The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous…”
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Feasibility study of a novel wireless localization technique using radiofrequency identification markers for small and deeply located lung lesions
Published in JTCVS techniques (01-04-2022)“…To evaluate the safety and efficacy of a novel wireless localization technique that uses radiofrequency identification markers for small and deep lung lesions…”
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Induced pluripotent stem cell–based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients
Published in BMJ open (02-12-2019)“…IntroductionAmyotrophic lateral sclerosis (ALS) is a progressive and severe neurodegenerative disease caused by motor neuron death. There have as yet been no…”
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Evaluation of respiratory rate monitoring performance using a home oxygen monitoring device among patients with interstitial lung disease and chronic obstructive pulmonary disease
Published in Sarcoidosis, vasculitis, and diffuse lung diseases (01-01-2022)“…Home monitoring devices have been developed to measure adherence to home oxygen therapy. In this study, we evaluated the performance of TeleOx , a commercially…”
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