Search Results - "松原, 秀三"
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組織液内抗生物質濃度の簡易測定法: ラットgranuloma pouchモデルの応用
Published in CHEMOTHERAPY (25-06-1980)“…実験小動物において組織液中の抗生物質濃度を測定することは, 組織液を採取する適当な手段に乏しい現状では容易でない。そこでラット背部にgranuloma pouchを作成し, そこに貯留する浸出液が代替組織液として応用しうるかどうかを, 血清蛋白結合率が異なるβ-lactam抗生物質を用いて検討した。その結果,…”
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ラット腎盂腎炎モデル作成に関する研究: とくにBEA前処置について
Published in CHEMOTHERAPY (25-03-1979)Get full text
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腎機能障害時におけるCeftezoleの排泄に関する基礎的ならびに臨床的検討
Published in CHEMOTHERAPY (1977)Get full text
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Isolation of Friend leukemia virus resistant line from non-inbred mouse colony
Published in The Japanese journal of experimental medicine (01-12-1975)“…Among a non-inbred ddY mouse colony, a small portion showed marked resistance to splenomegaly induction by Friend leukemia virus (FLV). The resistance to the…”
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Glucaronによるdibekacin毒性量投与後の体内蓄積抑制効果
Published in CHEMOTHERAPY (25-05-1981)“…240mg/kg以上のDKBを24時間給水制限ラットに筋注すると, 急性腎機能障害を惹起した。しかし, glucaronをDKB投与1時間前に経口投与すると, その腎障害の発現を有意に抑制した。glucaronの最小有効量は75~150mg/kgであった。また, DKB 130mg/kgの頻回投与毎にglucaron…”
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EXPERIMENTAL AND CLINICAL STUDIES ON THE EXCRETION OF CEFTEZOLE IN RENAL IMPAIRMENT
Published in CHEMOTHERAPY (25-10-1977)“…An experimental pyelonephritis model was prepared in rats by infecting E. coli C-11 ascendently from the urethral orifice 3 days after the intraperitoneal…”
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A NEW AND SIMPLE EXPERIMENTAL PYELONEPHRITIS MODEL IN RATS
Published in CHEMOTHERAPY (1979)“…Acute pyelonephritis was induced by retrograde bacterial infection in female rats treated with a renal toxic agent, 2-bromoethylamine hydrobromide (BEA). The…”
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EFFECT OF CEFTEZOLE AGAINST EXPERIMENTAL INFECTION IN THE INFLAMMATORY POUCH OF PATS
Published in CHEMOTHERAPY (1976)“…An experimental local infection system was established by inoculating E. coli, Strept. pneumoniae and Staph. aureus into the subcutancous aseptic inflammatory…”
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ANTIMICROBIAL ACTIVITY OF CEFTEZOLE, AND ITS ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION
Published in CHEMOTHERAPY (1976)“…Ceftezole (CTZ) is a new cephalosporin C antibiotic, which has a very similar chemical structure to cefazolin (CEZ). The antibacterial spectrum of CTZ was…”
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