双相障碍稳定期执行功能损害的神经影像学研究进展
双相障碍（BD）是一种高复发率、高致残率的慢性精神疾病，认知功能损害是其核心症状之一，并存在于病程的各个阶段。 神经影像学研究发现，大脑体积、白质纤维完整性、关键脑区脑血流信号及血氧饱和度等多是 BD 患者执行功能受损相关因素。该文 就 BD 稳定期患者执行功能损害的大脑结构及功能改变的现状和进展进行综述。...
Saved in:
| Published in: | 上海交通大学学报（医学版） Vol. 37; no. 8; pp. 1156 - 1160 |
|---|---|
| Main Author: | |
| Format: | Journal Article |
| Language: | Chinese |
| Published: |
上海交通大学医学院附属精神卫生中心心境障碍科,脑科学与技术研究中心,上海 200030
2017
|
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | 双相障碍（BD）是一种高复发率、高致残率的慢性精神疾病，认知功能损害是其核心症状之一，并存在于病程的各个阶段。 神经影像学研究发现，大脑体积、白质纤维完整性、关键脑区脑血流信号及血氧饱和度等多是 BD 患者执行功能受损相关因素。该文 就 BD 稳定期患者执行功能损害的大脑结构及功能改变的现状和进展进行综述。 |
|---|---|
| Bibliography: | 31-2045/R bipolar disorder; executive impairment; neuroimaging YANG Tao, ZHAO Guo-qing, FANG Yi-ru, CHEN Jun（Brain Science and Technology Research Center, Depressive Disorders Program, Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China ） Bipolar disorder （BD） is a chronic mental illness with high recurrence rate and disability. As one of the core symptoms, cognitive impairment may occurs at every stage of the disease. Evidence from the neuroimaging studies revealed that the abnormal brain volumes, the blood flow and oxygen saturation of key brain areas are related to executive impairment in patients with bipolar disorder. This article reviews current structural and functional neuroimaging studies about the executive impairment of patients with euthymic bipolar disorder and research progresses. |
| ISSN: | 1674-8115 |
| DOI: | 10.3969/j.issn.1674-8115.2017.08.021 |