Surgical outcomes and strategy of hypertrophic obstructive cardiomyopathy

Objective： To evaluate the surgical clinical results of hypertrophic obstructive cardiomyopathy. Methods： We retrospectively collected data on 24 patients who underwent surgical management in the past ten years in two hospitals in China and Madras Medical Mission in India. Myomectomy was carried out...

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Bibliographic Details
Published in:	Journal of Zhejiang University. B. Science Vol. 7; no. 2; pp. 148 - 153
Main Author:	朱亚彬 RAJAN S. KURIAN V.M. 刘志勇
Format:	Journal Article
Language:	English
Published:	China Springer Nature B.V 01-02-2006 Department of Thoracic and Cardiovascular Surgery, Affiliated Su Bei Hospital, Yangzhou University, Yangzhou 225001, China%Department of Thoracic and Cardiovascular Surgery, Madras Medical Mission, Moggapair East, Chennai 600037, India%Department of Thoracic and Cardiovascular Surgery, Affiliated Zhong Da Hospital, Southeast University, Nanjing 210009, China Zhejiang University Press
Subjects:	Adolescent Adult Aortic Valve - surgery Aortic Valve - transplantation Biomedicine Cardiac Surgical Procedures Cardiology Cardiomyopathy, Hypertrophic - surgery Catheters China Coronary Artery Bypass Female Heart Valve Prosthesis Heart Valve Prosthesis Implantation - methods Humans India Male Middle Aged Mitral Valve - pathology Mitral Valve - surgery Mitral Valve - transplantation Treatment Outcome 手术治疗收缩前运动肌肿瘤切除术肥厚性梗阻型心肌病 China India Systolic anterior motion Hypertrophic obstructive cardiomyopathy Myomectomy
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Summary:	Objective： To evaluate the surgical clinical results of hypertrophic obstructive cardiomyopathy. Methods： We retrospectively collected data on 24 patients who underwent surgical management in the past ten years in two hospitals in China and Madras Medical Mission in India. Myomectomy was carried out on all patients. Among them 3 patients underwent mitral valve replacement; 2 patients underwent mitral valve repair （anterior mitral leaflet plication）; 2 patients underwent aortic valve replacement; 1 patient underwent aortic valve repair; 2 patients underwent aortic root replacement; 1 patient underwent Bentall＇s procedure and 1 patient underwent coronary artery bypass grafting because of a breached muscle bridge, Results： One patient died of post-operative heart failure. The mean follow-up time was 4.3 years, There was significant improvement in the symptomatic status. Sixteen patients were asymptomatic with good effort tolerance and only four patients had New York heart association （NYHA） Classes Ⅰ-Ⅱ due to associated valvular lesions, Conclusion： Our experience proved that symptomatic hypertrophic obstructive cardiomyopathy or non-symptomatic hypertrophic obstructive cardiomyopathy with combined heart disease is indication for surgery as surgical intervention could get better clinical results in this kind of patients compared with other non-surgical method because it beneficially reduces the systolic anterior motion （SAM） of the mitral valve leaflet, which could not be avoided by other non-surgical treatment.
Bibliography:	R542.2 33-1356/Q Hypertrophic obstructive cardiomyopathy, Systolic anterior motion, Myomectomy ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1673-1581 1862-1783
DOI:	10.1631/jzus.2006.B0148