Search Results - "戸部, 昭広"

脳保護剤(フリーラジカル消去剤)エダラボンの研究開発 by 渡辺俊明a, 田中正彦b, 渡邉和俊c, 高松康雄d, 戸部昭広e

“…1978年にFlammら1)によって, フリーラジカルによる生体膜の脂質過酸化障害と虚血性脳損傷の関連性が初めて提唱された. 続いてSiesjo2)やDemopoulos3)は脳虚血におけるフリーラジカルの有害性を指摘,…”
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脳保護剤（フリーラジカル消去剤）エダラボンの研究開発 by 渡辺, 俊明, 田中, 正彦, 渡邉, 和俊, 高松, 康雄, 戸部, 昭広

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Triazine系化合物の薬理学的研究(第1報) 一般薬理作用の検討 by 戸部, 昭広

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Triazine系化合物の薬理学的研究(第4報)2-(Benzylidenehydrazino)-4-tert-butyl-6-piperazino-s-triazine(TR-35)の一般薬理作用 by 戸部, 昭広

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Triazine系化合物の薬理学的研究(第2報)2-Amino-4-Substituted-6-trifluoromethyl-s-triazine誘導体の向精神作用 by 戸部, 昭広, 角田, 勝

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Triazine系化合物の薬理学的研究(第3報)2-(Benzylidenehydrazino)-4-tert-butyl-6-piperazino-8-triazine(TR-35)の鎮痛抗炎症作用 by 戸部, 昭広, 梅津, 浩平

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Effects of terazosin on the blood pressure responses to tilting in conscious animals: comparison with prazosin by Bessho, H, Hara, Y, Kimura, Y, Narimatsu, A, Horii, D, Tobe, A

“…Inhibitory effects of terazosin on the compensatory blood pressure responses to tilting were studied in conscious rabbits and spontaneously hypertensive rats…”
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Effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016, bifemelane hydrochloride) on spontaneous motor activity under different experimental conditions by Tobe, A, Egawa, M, Saito, K, Hashimoto, N

“…Effects of MCI-2016 on SMA changes were examined under several experimental conditions (normal conditions, hypoxia and head injury). Under normal conditions,…”
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Effect of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (bifemelane hydrochloride, MCI-2016) on cerebral glucose metabolism by Inokuchi, T, Hirano, T, Kano, A, Egawa, M, Iida, S, Tobe, A

“…To predict the influence of MCI-2016 on cerebral energy metabolism, the activity of MCI-2016 on uptake of 2-deoxy-D-[14C]glucose ([14C]-DG) into the brain…”
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Fluoromethylated and Hydroxymethylated Derivatives of N-Methyl-D-aspartate Receptor Antagonist 1[1-(2-Thienyl)cyclohexyl]piperidine by TSUKIYAMA, Syuji, HASHIMOTO, Atsushi, KATAYAMA, Souta, NISHIKAWA, Toru, TOBE, Akihiro, MAEDA, Minoru

“…Derivatives with fluoromethyl and hydroxymethyl groups on the cyclohexyl ring of 1-[1-(2-thienyl)cyclohexyl]piperidine (TCP), a noncompetitive antagonist of…”
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Fluoromethylated and Hydroxymethylated Derivatives of N-Methyl-D-aspartate Receptor Antagonist 1-(1-(2-Thienyl)cyclohexyl)piperidine by TSUKIYAMA, Syuji, HASHIMOTO, Atsushi, KATAYAMA, Souta, NISHIKAWA, Toru, TOBE, Akihiro, MAEDA, Minoru

“…Derivatives with fluoromethyl and hydroxymethyl groups on the cyclohexyl ring of 1-(1-(2-thienyl)cyclohexyl) piperidine (TCP), a noncompetitive antagonist of…”
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Antihypertensive effect of betaxolol, a cardioselective beta-adrenoceptor antagonist, in experimental hypertensive rats by Bessho, H, Suzuki, J, Narimatsu, A, Tobe, A

“…Betaxolol is a highly selective beta 1-adrenoceptor antagonist without intrinsic sympathomimetic activity. In this study, the antihypertensive effect of…”
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Effects of betaxolol, a cardioselective beta-adrenoceptor antagonist, on ischemic myocardial energy and carbohydrate metabolism in dogs by Abe, Y, Narimatsu, A, Tobe, A

“…The effect of betaxolol, a beta 1-adrenoceptor antagonist, on ischemic myocardial metabolism was studied in dog hearts subjected to an occlusion of the left…”
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Antihypertensive effect of betaxolol, a cardioselective beta-adrenoceptor antagonist, in renal hypertensive dogs by Bessho, H, Suzuki, J, Kitada, Y, Narimatsu, A, Tobe, A

“…The antihypertensive effect of betaxolol, a highly selective beta 1-adrenoceptor antagonist, was investigated in renal hypertensive dogs, and the mechanism was…”
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Effect of MCI-2016 (bifemelane hydrochloride) on cerebral ischemia following ligation of both common carotid arteries in Mongolian gerbils by Egawa, M, Hashimoto, N, Tobe, A

“…Cerebral protective effect of MCI-2016 and influence of age on survival time in the cerebral ischemic model induced by bilateral-carotid-arterial ligation in…”
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General pharmacological action of 4-(o-benzylphenoxy)-N-methylamine hydrochloride (bifemelane hydrochloride, MCI-2016)--influence on the central nervous system by Tobe, A, Egawa, M, Hashimoto, N, Nagai, R, Ishikawa, K, Yamazaki, S, Tanaka, T

“…General pharmacological action of 4-(o-Benzylphenoxy)-N-methylbutylamine hydrochloride (bifemelane hydrochloride, MCI-2016) was examined with regard to the…”
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Effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016, bifemelane hydrochloride) on coagulation, fibrinolysis, hemolysis, hemorheological properties and platelet aggregation by Tamao, Y, Hara, H, Umezu, K, Ito, J, Doi, A, Sudo, A, Hirata, T, Mineo, K, Tobe, A

“…MCI-2016 showed little influence on coagulation (APTT) and fibrinolysis (plasma clot lysis activated by urokinase) at doses (concentrations) as high as 300…”
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