Search Results - "小川, 春樹"

Ceftezoleのラット炎症pouch内実験的感染に対する効果 by 松原, 秀三, 遠藤, 久男, 小川, 春樹, 小山, 憲次朗

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ラット腎盂腎炎モデル作成に関する研究: とくにBEA前処置について by 松原, 秀三, 遠藤, 久男, 二木, 力夫, 小川, 春樹, 小山, 憲次朗

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腎機能障害時におけるCeftezoleの排泄に関する基礎的ならびに臨床的検討 by 米瀬, 泰行, 徳江, 章彦, 松島, 正浩, 松原, 秀三, 原田, 祐輔, 遠藤, 久男, 小川, 春樹, 小山, 憲次朗

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Glucaronによるdibekacin毒性量投与後の体内蓄積抑制効果 by 遠藤, 久男, 松原, 秀三, 岡崎, 博司, 小川, 春樹

“…240mg/kg以上のDKBを24時間給水制限ラットに筋注すると, 急性腎機能障害を惹起した。しかし, glucaronをDKB投与1時間前に経口投与すると, その腎障害の発現を有意に抑制した。glucaronの最小有効量は75～150mg/kgであった。また, DKB 130mg/kgの頻回投与毎にglucaron…”
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組織液内抗生物質濃度の簡易測定法: ラットgranuloma pouchモデルの応用 by 松原, 秀三, 遠藤, 久男, 岡崎, 博司, 小川, 春樹

“…実験小動物において組織液中の抗生物質濃度を測定することは, 組織液を採取する適当な手段に乏しい現状では容易でない。そこでラット背部にgranuloma pouchを作成し, そこに貯留する浸出液が代替組織液として応用しうるかどうかを, 血清蛋白結合率が異なるβ-lactam抗生物質を用いて検討した。その結果,…”
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Ceftezoleの抗菌作用ならびに吸収, 分布, 代謝および排泄 by 小山, 憲次朗, 小川, 春樹, 野藤, 隆夫, 根橋, 敏行, 原田, 祐輔, 松原, 秀三, 遠藤, 久男, 斎藤, 元男, 柿本, 守夫, 鈴木, 清吉, 金子, 康子, 五島, 瑳智子

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EXPERIMENTAL AND CLINICAL STUDIES ON THE EXCRETION OF CEFTEZOLE IN RENAL IMPAIRMENT by YONESE, YASUYUKI, TOKUE, AKIHIKO, MATSUSHIMA, MASAHIRO, MATSUBARA, SHUZO, HARADA, YUSUKE, ENDO, HISAO, OGAWA, HARUKI, KOYAMA, KENJIRO

“…An experimental pyelonephritis model was prepared in rats by infecting E. coli C-11 ascendently from the urethral orifice 3 days after the intraperitoneal…”
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Effects of Derivatives of Hydroxypyruvaldehyde Phenylosazone on the Ca2+-Adenosine Triphosphatase Activity of Porcine Erythrocyte Membrane by NAKABAYASHI, TOSHIKATSU, IKEZAWA, HIROH, OGAWA, HARUKI, SHINDO, MINORU, MATSUNAGA, ISAO

“…Thirteen derivatives of hydroxypyruvaldehyde phenylosazone were tested for their effects on the Ca2+-adenosine triphosphatase (ATPase) activity of porcine…”
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Effects of Derivatives of Hydroxypyruvaldehyde Phenylosazone on Bovine Erythrocyte Membrane. II. Stabilization of Sphingomyelinase C-Treated or Untreated Cells Examined by Coil Planet Centrifugation and Electron Microscopy by IKEZAWA, HIROH, MIZUNO, MAKOTO, INOUE, MAKOTO, TAGUCHI, RYO, OGAWA, HARUKI, SHINDO, MINORU, MATSUNAGA, ISAO

“…The effects of hydroxypyruvaldehyde phenylosazone (1) and its CH3-and Cl-derivatives (2-5) on the osmotic fragility of bovine erythrocytes treated or untreated…”
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Effects of derivatives of hydroxypyruvaldehyde phenylosazone on bovine erythrocyte membrane. I. Influence on the osmotic fragility and morphology by Ikezava, H, Mizuno, M, Nakabayashi, T, Ogawa, H, Shindo, M, Matsunaga, I

“…Thirteen derivatives of hydroxypyruvaldehyde phenylosazone were tested for effects on bovine erythrocyte membrane. Six drugs, including hydroxypyruvaldehyde…”
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A NEW AND SIMPLE EXPERIMENTAL PYELONEPHRITIS MODEL IN RATS by MATSUBARA, SHUZO, ENDO, HISAO, NIKI, RIKIO, OGAWA, HARUKI, KOYAMA, KENJIRO

“…Acute pyelonephritis was induced by retrograde bacterial infection in female rats treated with a renal toxic agent, 2-bromoethylamine hydrobromide (BEA). The…”
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INHIBITORY EFFECT OF A STREPTOCOCCAL PREPARATION (OK-432) ON INDUCTION OF SPLENOMEGALY BY FRIEND LEUKEMIA VIRUS by SUZUKI, Seikichi, YAMAMOTO, Akihiro, OGAWA, Haruki

“…Pretreatment with OK-432 showed marked suppresive effect on splenomegaly induced by Friend leukemia virus in mice. Post-treatment was less effective than…”
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EFFECT OF CEFTEZOLE AGAINST EXPERIMENTAL INFECTION IN THE INFLAMMATORY POUCH OF PATS by MATSUBARA, SHUZO, ENDO, HISAO, OGAWA, HARUKI, KOYAMA, KENJIRO

“…An experimental local infection system was established by inoculating E. coli, Strept. pneumoniae and Staph. aureus into the subcutancous aseptic inflammatory…”
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Effects of derivatives of hydroxypyruvaldehyde phenylosazone on the Ca2+-adenosine triphosphatase activity of porcine erythrocyte membrane by Nakabayashi, T, Ikezawa, H, Ogawa, H, Shindo, M, Matsunaga, I

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INHIBITORY EFFECT OF A STREPTOCOCCAL PREPARATION (OK-432) ON THE NUCLEIC ACID SYNTHESIS IN TUMOR CELLS IN VITRO by ONO, Tetsuo, KURATA, Sumiko, WAKABAYASHI, Kiyoshige, SUGAWARA, Yutaka, SAITO, Motoo, OGAWA, Haruki

“…The in vitro effect of OK-432 (NSC-B116209), the lyophilized preparation of penicillin-treated cell suspension of a low virulent strain, Su, of Streptococcus…”
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ANTIMICROBIAL ACTIVITY OF CEFTEZOLE, AND ITS ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION by KOYAMA, KENJIRO, OGAWA, HARUKI, NOTO, TAKAO, NEHASHI, TOSHIYUKI, HARADA, YUSUKE, MATSUBARA, SHUZO, ENDO, HISAO, SAITO, MOTOO, KAKIMOTO, MORIO, SUZUKI, SEIKICHI, KANEKO, YASUKO, GOTO, SACHIKO

“…Ceftezole (CTZ) is a new cephalosporin C antibiotic, which has a very similar chemical structure to cefazolin (CEZ). The antibacterial spectrum of CTZ was…”
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