Factors Associated with Self-reported Medication Adherence in Japanese Community-dwelling Elderly Individuals: The Nakajima Study

Medication non-adherence in the elderly population is a major problem, preventing them from obtaining optimal therapeutic effects. Identifying the factors affecting medication adherence is crucial for improving and maintaining health among the elderly population and enhance healthcare economy. The p...

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Published in:	YAKUGAKU ZASSHI Vol. 141; no. 5; pp. 751 - 759
Main Authors:	石田, 奈津子, 徳用, 百合奈, 菅, 幸生, 篠原, もえ子, 阿部, 智絵美, 柚木, 颯偲, 森, 彩香, 堀本, 真以, 林, 幸司, 岩佐, 和夫, 横川, 正美, 石宮, 舞, 中村, 博幸, 駒井, 清暢, 松下, 良, 石﨑, 純子, 山田, 正仁
Format:	Journal Article
Language:	Japanese
Published:	Japan 公益社団法人日本薬学会 01-05-2021 Pharmaceutical Society of Japan
Subjects:	drug profile book medication adherence older pharmacist QOL pharmacist older medication adherence drug profile book QOL
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Summary:	Medication non-adherence in the elderly population is a major problem, preventing them from obtaining optimal therapeutic effects. Identifying the factors affecting medication adherence is crucial for improving and maintaining health among the elderly population and enhance healthcare economy. The purpose of this study was to examine the prevalence of self-reported medication adherence, and identify the associated factors and the influence of health-related quality of life (HRQOL) in the Japanese community-dwelling elderly population. This cross-sectional study was part of the Nakajima study and targeted inhabitants aged >= 60 years who underwent health examinations in 2017. Data regarding medication adherence were acquired through interviews and self-administered questionnaires. Medication adherence were assessed using a visual analog scale, and HRQOL was assessed by EuroQol five-dimensional questionnaire with 3 levels. Among the 455 participants, low and high medication adherence were seen in 9.7% and 66.2% of the participants, respectively (visual analog scores < 80% and >= 95%, respectively). Medication adherence was significantly lower in participants taking medications 3 times daily than in those taking medications once or twice daily; a regimen involving drug administration 3 times daily had significantly lower odds of medication adherence. The use of a drug profile book and HRQOL had significant positive association with medication adherence. Our results suggest that low dosing frequency and using a drug profile book was positively associated with medication adherence among elderly persons, which in turn could enhance their QOL.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0031-6903 1347-5231
DOI:	10.1248/yakushi.20-00254