Search Results - "Ștefanescu, Raluca"
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JWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models
Published in Scientific reports (15-07-2024)“…Chemotherapy-induced neuropathic pain (CINP), a condition with unmet treatment needs, affects over half of cancer patients treated with chemotherapeutics…”
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Observation of Intact and Proteolytically Cleaved Amyloid-Beta (1–40)-Oleuropein Noncovalent Complex at Neutral pH by Mass Spectrometry
Published in Molecules (Basel, Switzerland) (28-05-2021)“…Mass spectrometry analyses carried out on mass spectrometers equipped with soft ionization sources demonstrated their utility in the assessment of the…”
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Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review
Published in Pain research & management (01-01-2018)“…Recently, numerous side effects of synthetic drugs have lead to using medicinal plants as a reliable source of new therapy. Pain is a global public health…”
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Influence of Stainless Needle Electrodes and Silver Disk Electrodes over the Interhemispheric Cerebral Coherence Value in Vigil Dogs
Published in Sensors (Basel, Switzerland) (16-11-2018)“…Electroencephalography (EEG) is an objective diagnostic tool in the evaluation of cerebral functionality, both in human and veterinary medicine. For EEG…”
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Very-Low-Frequency Spike-Wave Complex Partial Motor Seizure Mimicking Canine Idiopathic Head Tremor Syndrome in a Dog
Published in Veterinary sciences (01-07-2023)“…Canine idiopathic head tremor syndrome (CIHTS) represents a benign condition characterized by episodic, uncontrolled movement of the head. Even though the…”
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Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?
Published in Pharmaceutics (01-11-2021)“…The most important discoveries in pharmacology, such as certain classes of analgesics or chemotherapeutics, started from natural extracts which have been found…”
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Strategies for the Diagnosis of Granulocytic Anaplasmosis in Two Naturally Infected Dogs
Published in Animals (Basel) (01-01-2024)“…This study describes granulocytic anaplasmosis in two dogs naturally infected with . The 3-year-old dogs (male and female) came from the same household and…”
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Acute Toxicity and Pharmacokinetic Profile of an EU-GMP-Certified Cannabis sativa L. in Rodents
Published in Pharmaceuticals (Basel, Switzerland) (03-05-2023)“…The conundrum of 's applications for therapeutical purposes is set apart by the hundreds of known and commercially available strains, the social, cultural and…”
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Validation results of satellite mock-up capturing experiment using nets
Published in Acta astronautica (01-05-2017)“…The PATENDER activity (Net parametric characterization and parabolic flight), funded by the European Space Agency (ESA) via its Clean Space initiative, was…”
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Contributions of Mass Spectrometry to the Identification of Low Molecular Weight Molecules Able to Reduce the Toxicity of Amyloid-β Peptide to Cell Cultures and Transgenic Mouse Models of Alzheimer's Disease
Published in Molecules (Basel, Switzerland) (24-03-2019)“…Alzheimer's Disease affects approximately 33 million people worldwide and is characterized by progressive loss of memory at the cognitive level. The formation…”
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Secondary Metabolites from Plants Possessing Inhibitory Properties against Beta-Amyloid Aggregation as Revealed by Thioflavin-T Assay and Correlations with Investigations on Transgenic Mouse Models of Alzheimer's Disease
Published in Biomolecules (Basel, Switzerland) (06-06-2020)“…Alzheimer's disease is a neurodegenerative disorder for which there is a continuous search of drugs able to reduce or stop the cognitive decline. Beta-amyloid…”
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Acute idiopathic polyradiculoneuritis with secondary arterial hypertension in a 5-year-old male Siberian Husky
Published in The Veterinary quarterly (01-01-2020)“…Acute canine idiopathic polyradiculoneuritis (ACIP) is one of the most common generalised neuromuscular diseases affecting dogs. In this report, we describe a…”
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The Value of Morphologic Study (MRI) of the Median Nerve in Stadialization and Treatment of the Carpal Tunnel Syndrome
Published in Medicina modernă (Bucharest, Romania) (30-12-2021)“…Carpal tunnel syndrome is a sensitive neuropathy of the upper limb caused by chronic compression of the median nerve. The presented study focused on…”
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Seronegative Myasthenia Gravis with Concomitant SARS-CoV-2 Infection in a Dog
Published in Veterinary sciences (24-06-2022)“…Myasthenia gravis (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack…”
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Brainstem Auditory Evoked Potentials in Raccoon Dogs ( Nyctereutes procynoides )
Published in Animals (Basel) (01-02-2020)“…Raccoon dogs ( ) are canids indigenous to Eastern Asia being one of the most invasive non-native animals in Europe and potential vectors for several hazardous…”
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Subunit Architecture of Multiprotein Assemblies Determined Using Restraints from Gas-Phase Measurements
Published in Structure (London) (09-09-2009)“…Protein interaction networks are becoming an increasingly important area of research within structural genomics. Here we present an ion mobility-mass…”
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Challenges and Opportunities in Preclinical Research of Synthetic Cannabinoids for Pain Therapy
Published in Medicina (Kaunas, Lithuania) (09-01-2020)“…Cannabis has been used in pain management since 2900 BC. In the 20th century, synthetic cannabinoids began to emerge, thus opening the way for improved…”
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Implications of the Serine Protease HtrA1 in Amyloid Precursor Protein Processing
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2005)“…The defining features of the widely conserved HtrA (high temperature requirement) family of serine proteases are the combination of a catalytic protease domain…”
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Morphological and Biochemical Answer of the Wheat Seeds at Treatment with 2,4-Dinitrophenol and Potassium Iodate
Published in Brazilian Archives of Biology and Technology (01-01-2016)“…Oxidative stress can be regarded as an imbalance between the amount of reactive oxygen species (ROS) and the ability of a biological system to eliminate the…”
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Molecular characterization of the [beta]-amyloid(4-10) epitope of plaque specific A[beta] antibodies by affinity-mass spectrometry using alanine site mutation
Published in Journal of peptide science (01-01-2018)“…Alzheimer disease is a neurodegenerative disease affecting an increasing number of patients worldwide. Current therapeutic strategies are directed to molecules…”
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