Search Results - "Žárský, Vojtěch"
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Evolution of the Tim17 protein family
Published in Biology direct (19-10-2016)“…The Tim17 family of proteins plays a fundamental role in the biogenesis of mitochondria. Three Tim17 family proteins, Tim17, Tim22, and Tim23, are the central…”
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Cryogenian Glacial Habitats as a Plant Terrestrialisation Cradle - The Origin of the Anydrophytes and Zygnematophyceae Split
Published in Frontiers in plant science (27-01-2022)“…For tens of millions of years (Ma), the terrestrial habitats of Snowball Earth during the Cryogenian period (between 720 and 635 Ma before…”
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Targeting of tail‐anchored proteins to Trichomonas vaginalis hydrogenosomes
Published in Molecular microbiology (01-03-2019)“…Summary Tail‐anchored (TA) proteins are membrane proteins that are found in all domains of life. They consist of an N‐terminal domain that performs various…”
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Evolutionary loss of peroxisomes--not limited to parasites
Published in Biology direct (23-12-2015)“…Peroxisomes are ubiquitous eukaryotic organelles that compartmentalize a variety of metabolic pathways that are primarily related to the oxidative metabolism…”
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Lateral gene transfer of p‐cresol‐ and indole‐producing enzymes from environmental bacteria to Mastigamoeba balamuthi
Published in Environmental microbiology (01-03-2017)“…Summary p‐Cresol and indole are volatile biologically active products of the bacterial degradation of tyrosine and tryptophan respectively. They are typically…”
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Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol
Published in PLoS pathogens (15-11-2021)“…Entamoeba histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are…”
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Lateral gene transfer of p ‐cresol‐ and indole‐producing enzymes from environmental bacteria to M astigamoeba balamuthi
Published in Environmental microbiology (01-03-2017)“…Summary p‐ Cresol and indole are volatile biologically active products of the bacterial degradation of tyrosine and tryptophan respectively. They are typically…”
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8
Triplet-pore structure of a highly divergent TOM complex of hydrogenosomes in Trichomonas vaginalis
Published in PLoS biology (04-01-2019)“…Mitochondria originated from proteobacterial endosymbionts, and their transition to organelles was tightly linked to establishment of the protein import…”
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The Mastigamoeba balamuthi Genome and the Nature of the Free-Living Ancestor of Entamoeba
Published in Molecular biology and evolution (19-05-2021)“…Abstract The transition of free-living organisms to parasitic organisms is a mysterious process that occurs in all major eukaryotic lineages. Parasites display…”
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A Eukaryote without a Mitochondrial Organelle
Published in Current biology (23-05-2016)“…The presence of mitochondria and related organelles in every studied eukaryote supports the view that mitochondria are essential cellular components. Here, we…”
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Probing the Biology of Giardia intestinalis Mitosomes Using In Vivo Enzymatic Tagging
Published in Molecular and cellular biology (01-08-2015)“…Giardia intestinalis parasites contain mitosomes, one of the simplest mitochondrion-related organelles. Strategies to identify the functions of mitosomes have…”
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Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases
Published in Molecular & cellular proteomics (01-01-2022)“…The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in…”
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A hybrid TIM complex mediates protein import into hydrogenosomes of Trichomonas vaginalis
Published in BMC biology (03-06-2024)“…Hydrogenosomes are a specific type of mitochondria that have adapted for life under anaerobiosis. Limited availability of oxygen has resulted in the loss of…”
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ancestral bacterial division system is widespread in eukaryotic mitochondria
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2015)“…Bacterial division initiates at the site of a contractile Z-ring composed of polymerized FtsZ. The location of the Z-ring in the cell is controlled by a system…”
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15
Contrasting outcomes of genome reduction in mikrocytids and microsporidians
Published in BMC biology (06-06-2023)“…Intracellular symbionts often undergo genome reduction, losing both coding and non-coding DNA in a process that ultimately produces small, gene-dense genomes…”
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Anaerobic peroxisomes in Mastigamoeba balamuthi
Published in Proceedings of the National Academy of Sciences - PNAS (28-01-2020)“…The adaptation of eukaryotic cells to anaerobic conditions is reflected by substantial changes to mitochondrial metabolism and functional reduction…”
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Dynamic secretome of Trichomonas vaginalis: Case study of β-amylases
Published in Molecular & cellular proteomics (01-02-2018)“…The secretion of virulence factors by parasitic protists into the host environment plays a fundamental role in multifactorial host–parasite interactions…”
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Cysteine peptidases of Eudiplozoon nipponicum: a broad repertoire of structurally assorted cathepsins L in contrast to the scarcity of cathepsins B in an invasive species of haematophagous monogenean of common carp
Published in Parasites & vectors (06-03-2018)“…Cysteine peptidases of clan CA, family C1 account for a major part of proteolytic activity in the haematophagous monogenean Eudiplozoon nipponicum. The full…”
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Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system
Published in Nature communications (19-05-2021)“…The type 2 secretion system (T2SS) is present in some Gram-negative eubacteria and used to secrete proteins across the outer membrane. Here we report that…”
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The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista
Published in BMC ecology and evolution (19-03-2021)“…Nbp35-like proteins (Nbp35, Cfd1, HCF101, Ind1, and AbpC) are P-loop NTPases that serve as components of iron-sulfur cluster (FeS) assembly machineries. In…”
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