Search Results - "Švíglerová, Jitka"

Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure by Jarkovská, Dagmar, Miklovič, Matúš, Švíglerová, Jitka, Červenka, Luděk, Škaroupková, Petra, Melenovský, Vojtěch, Štengl, Milan

“…Chronic volume overload induces multiple cardiac remodeling processes that finally result in eccentric cardiac hypertrophy and heart failure. We have…”
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TdP Incidence in Methoxamine-Sensitized Rabbit Model Is Reduced With Age but Not Influenced by Hypercholesterolemia by Nalos, Lukáš, Jarkovská, Dagmar, Švíglerová, Jitka, Süß, Annabell, Záleský, Jakub, Rajdl, Daniel, Krejčová, Milada, Kuncová, Jitka, Rosenberg, Josef, Štengl, Milan

“…Metabolic syndrome is associated with hypercholesterolemia, cardiac remodeling, and increased susceptibility to ventricular arrhythmias. Effects of…”
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Right versus left ventricular remodeling in heart failure due to chronic volume overload by Havlenova, Tereza, Skaroupkova, Petra, Miklovic, Matus, Behounek, Matej, Chmel, Martin, Jarkovska, Dagmar, Sviglerova, Jitka, Stengl, Milan, Kolar, Michal, Novotny, Jiri, Benes, Jan, Cervenka, Ludek, Petrak, Jiri, Melenovsky, Vojtech

“…Mechanisms of right ventricular (RV) dysfunction in heart failure (HF) are poorly understood. RV response to volume overload (VO), a common contributing factor…”
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Effects of clinically relevant acute hypercapnic and metabolic acidosis on the cardiovascular system: an experimental porcine study by Stengl, Milan, Ledvinova, Lenka, Chvojka, Jiri, Benes, Jan, Jarkovska, Dagmar, Holas, Jaromir, Soukup, Patrik, Sviglerová, Jitka, Matejovic, Martin

“…Hypercapnic acidosis (HCA) that accompanies lung-protective ventilation may be considered permissive (a tolerable side effect), or it may be therapeutic by…”
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Excess ischemic tachyarrhythmias trigger protection against myocardial infarction in hypertensive rats by Neckář, Jan, Alánová, Petra, Olejníčková, Veronika, Papoušek, František, Hejnová, Lucie, Šilhavý, Jan, Behuliak, Michal, Bencze, Michal, Hrdlička, Jaroslav, Vecka, Marek, Jarkovská, Dagmar, Švíglerová, Jitka, Mistrová, Eliška, Štengl, Milan, Novotný, Jiří, Ošťádal, Bohuslav, Pravenec, Michal, Kolář, František

“…Increased level of C-reactive protein (CRP) is a risk factor for cardiovascular diseases, including myocardial infarction and hypertension. Here, we analyzed…”
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Mitochondrial dysfunction in kidney cortex and medulla of subtotally nephrectomized rats by Jedlička, J, Grundmanová, M, Švíglerová, J, Tůma, Z, Nalos, L, Rajdl, D, Štengl, M, Kuncová, J

“…Five-sixths nephrectomy is a widely used experimental model of chronic kidney disease (CKD) that is associated with severe mitochondrial dysfunction of the…”
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Cellular Mechanisms of Myocardial Depression in Porcine Septic Shock by Jarkovska, Dagmar, Markova, Michaela, Horak, Jan, Nalos, Lukas, Benes, Jan, Al-Obeidallah, Mahmoud, Tuma, Zdenek, Sviglerova, Jitka, Kuncova, Jitka, Matejovic, Martin, Stengl, Milan

“…The complex pathogenesis of sepsis and septic shock involves myocardial depression, the pathophysiology of which, however, remains unclear. In this study,…”
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Cardiac remodeling in rats with renal failure shows interventricular differences by Svíglerová, Jitka, Kuncová, Jitka, Nalos, Lukás, Holas, Jaromír, Tonar, Zbynek, Rajdl, Daniel, Stengl, Milan

“…Chronic renal failure (CRF) is associated with an increased incidence of cardiovascular diseases. Intensive research revealed a number of alterations in the…”
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SOFA Score, Hemodynamics and Body Temperature Allow Early Discrimination between Porcine Peritonitis-Induced Sepsis and Peritonitis-Induced Septic Shock by Al-Obeidallah, Mahmoud, Jarkovská, Dagmar, Valešová, Lenka, Horák, Jan, Jedlička, Jan, Nalos, Lukáš, Chvojka, Jiří, Švíglerová, Jitka, Kuncová, Jitka, Beneš, Jan, Matějovič, Martin, Štengl, Milan

“…Porcine model of peritonitis-induced sepsis is a well-established clinically relevant model of human disease. Interindividual variability of the response often…”
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Parasympathetic regulation of heart rate in rats after 5/6 nephrectomy is impaired despite functionally intact cardiac vagal innervation by Kuncová, Jitka, Švíglerová, Jitka, Kummer, Wolfgang, Rajdl, Daniel, Chottová-Dvořáková, Magdalena, Tonar, Zbyněk, Nalos, Lukáš, Štengl, Milan

“…Background. Chronic renal failure is frequently associated with a high risk of sudden cardiac death due to dysfunction of the autonomic nervous system. The…”
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Plasma and Tissue Levels of Neuropeptide Y in Experimental Septic Shock: Relation to Hemodynamics, Inflammation, Oxidative Stress, and Hemofiltration by Kuncová, Jitka, Sýkora, Roman, Chvojka, Jiří, Švíglerová, Jitka, Štengl, Milan, Kroužecký, Aleš, Nalos, Lukáš, Matějovič, Martin

“…Neuropeptide Y (NPY), a potent vasoconstrictor released from the sympathetic nerves, has been suggested to counterbalance sepsis‐induced vasodilation. Thus,…”
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Alteration of the Cardiac Sympathetic Innervation Is Modulated by Duration of Diabetes in Female Rats by Švíglerová, Jitka, Mudra, Jiří, Tonar, Zbyněk, Slavíková, Jana, Kuncová, Jitka

“…To evaluate the sympathetic innervation of the female diabetic heart, resting heart rate and sympathetic tone were assessed in vivo, and effect of tyramine on…”
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Down-regulation of vasoactive intestinal peptide and altered expression of its receptors in rat diabetic cardiomyopathy by Dvoráková, Magdalena Chottová, Pfeil, Uwe, Kuncová, Jitka, Svíglerová, Jitka, Galvis, Giovanni, Krasteva, Gabriela, König, Peter, Grau, Veronika, Slavíková, Jana, Kummer, Wolfgang

“…Vasoactive intestinal peptide (VIP) is a vasorelaxant peptide that addresses two receptor subtypes, VPAC1 and VPAC2. It stimulates insulin secretion and…”
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Aorta Remodelling Associated with Calcitonin Gene Related Peptide Concentration in Rats with Arterial Hypertension by Kochová, Petra, Tonar, Zbyněk, Matějka, Vít M., Švíglerová, Jitka, Štengl, Milan, Kuncová, Jitka

“…Long-term hypertension in arteries leads to remodelling of the arterial wall. We focused on morphological changes in the wall of the subrenal aorta in rats…”
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Heterogenous changes in neuropeptide Y, norepinephrine and epinephrine concentrations in the hearts of diabetic rats by Kuncová, Jitka, Švíglerová, Jitka, Tonar, Zbyněk, Slavíková, Jana

“…The changes in concentrations of neuropeptide Y (NPY), norepinephrine and epinephrine were investigated in the rat hearts 1, 2, 4, 6, 9 and 12 months after…”
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Vagus Nerve Stimulation Attenuates Multiple Organ Dysfunction in Resuscitated Porcine Progressive Sepsis by Kohoutova, Michaela, Horak, Jan, Jarkovska, Dagmar, Martinkova, Vendula, Tegl, Vaclav, Nalos, Lukas, Vistejnova, Lucie, Benes, Jan, Sviglerova, Jitka, Kuncova, Jitka, Matejovic, Martin, Stengl, Milan

“…OBJECTIVES:To investigate the potential benefits of vagus nerve stimulation in a clinically-relevant large animal model of progressive sepsis…”
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Heart-rate variability depression in porcine peritonitis-induced sepsis without organ failure by Jarkovska, Dagmar, Valesova, Lenka, Chvojka, Jiri, Benes, Jan, Danihel, Vojtech, Sviglerova, Jitka, Nalos, Lukas, Matejovic, Martin, Stengl, Milan

“…Depression of heart-rate variability (HRV) in conditions of systemic inflammation has been shown in both patients and experimental animal models and HRV has…”
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Reduced L-type calcium current in ventricular myocytes from pigs with hyperdynamic septic shock by Stengl, Milan, Bartak, Frantisek, Sykora, Roman, Chvojka, Jiri, Benes, Jan, Krouzecky, Ales, Novak, Ivan, Sviglerova, Jitka, Kuncova, Jitka, Matejovic, Martin

“…OBJECTIVE:To hypothesize that reduced L-type calcium current with consequent shortening of cardiac repolarization is present in a clinically relevant porcine…”
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Structure-activity relationship and cardiac safety of 2-aryl-2-(pyridin-2-yl)acetamides as a new class of broad-spectrum anticonvulsants derived from Disopyramide by Dawidowski, Maciej, Król, Marek, Szulczyk, Bartłomiej, Chodkowski, Andrzej, Podsadni, Piotr, Konopelski, Piotr, Ufnal, Marcin, Szuberski, Piotr, Wróbel, Martyna Zofia, Zhang, Yihong, El Harchi, Aziza, Hancox, Jules C., Jarkovska, Dagmar, Mistrova, Eliska, Sviglerova, Jitka, Štengl, Milan, Popowicz, Grzegorz M., Turło, Jadwiga

“…[Display omitted] •New anticonvulsant agents were derived from cardioactive Disopyramide (DISO).•The compounds revealed high anticonvulsant activity in animal…”
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Heart Rate Variability in Porcine Progressive Peritonitis-Induced Sepsis by Jarkovska, Dagmar, Valesova, Lenka, Chvojka, Jiri, Benes, Jan, Sviglerova, Jitka, Florova, Blanka, Nalos, Lukas, Matejovic, Martin, Stengl, Milan

“…Accumulating evidence suggests that heart rate variability (HRV) alterations could serve as an indicator of sepsis progression and outcome, however, the…”
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