Search Results - "Štalc, Anton"
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Evaluation of two experimental venous thrombosis models in the rat
Published in Thrombosis research (2005)Get full text
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Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models
Published in Thrombosis and haemostasis (01-03-2005)“…The antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold (LK-732, LK-639 and LK-731) and their amidoxime prodrugs…”
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Early events in TNFa -- p55 receptor interactions -- experiments with TNF dimers
Published in Pflügers Archiv (01-07-2000)“…The first essential step in TNF signal transduction is believed to be clustering of the membrane bound receptors around the trimeric TNF molecule. To check if…”
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Soluble tumor necrosis factor receptor I (sTNFRI) as a prognostic factor in melanoma patients in Slovene population
Published in Pflügers Archiv (2000)“…Tumor necrosis factor alpha (TNF-alpha) and its receptors (TNFRI and TNFRII) which exist in soluble form as a product of cleavage of the extracellular domain…”
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Improvement of potential therapeutic value of tumor necrosis-alpha (TNF-alpha) by charge modulation in the tip region
Published in European cytokine network (Montrouge) (01-01-2005)“…Analysis of published data reveals that the introduction of more basic amino acid residues in the flexible N-terminal region of the human tumour necrosis…”
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Human granulocyte colony stimulating factor (hG-CSF) expressed by methylotrophic yeast pichia pastoris
Published in Pflügers Archiv (01-01-2001)“…Human granulocyte colony stimulating factor (hG-CSF) was expressed in the methylotrophic yeast Pichia pastoris, using two different constructs which resulted…”
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Early events in TNFa - p55 receptor interactions-experiments with TNF dimers
Published in Pflügers Archiv (01-01-2000)“…The first essential step in TNF signal transduction is believed to be clustering of the membrane bound receptors around the trimeric TNF molecule. To check if…”
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N-{trans-2-[[2‘-(Acetylamino)cyclohexyl]oxy]acetyl}-l-alanyl-d-glutamic Acid: A Novel Immunologically Active Carbocyclic Muramyl Dipeptide Analogue
Published in Journal of medicinal chemistry (12-02-1998)“…A novel non-pyrogenic carbocyclic muramyl dipeptide (MDP) analogue, N-{trans-2-[[2‘-(acetylamino)cyclohexyl]oxy]acetyl}-l-alanyl-d-glutamic acid, was obtained…”
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A contribution to the mechanism of action of SAD-128
Published in Biochemical pharmacology (01-12-1990)“…SAD-128 was found to be an effective protector of acetylcholinesterase against inhibition by soman, due to its ability to function as a reversible inhibitor…”
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Allosteric effects of phenyltrimethylammonium and propidium on acetylcholinesterase active site
Published in Pflügers Archiv (1996)“…Different spin labelled fluorophosphates and fluorophosphonates with different chain length were investigated with respect to their sensitivity to the…”
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The influence of soman simulator on reactivation by HI-6 of soman-inhibited acetylcholinesterase in preparations of rat and human skeletal muscle
Published in Biochemical pharmacology (26-01-1993)“…The aim of our study was to elucidate the phenomenon called "soman depot". Our investigations were focused on the depot formed in the skeletal muscle and on…”
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Modification of TNF-alpha pharmacokinetics in SA-1 tumor-bearing mice
Published in International journal of cancer (19-08-1993)“…Fibrosarcoma-SA-I-tumor-bearing mice were treated s.c. in the vicinity of tumors (peri-tumorally) or intravenously, with recombinant human TNF-alpha lacking 1…”
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Soluble tumor necrosis factor receptor I (sTNFRI) as a prognostic factor in melanoma patients in Slovene population
Published in Pflügers Archiv (01-01-2000)“…Tumor necrosis factor α (TNF-α) and its receptors (TNFRI and TNFRII) which exist in soluble form as a product of cleavage of the extracellular domain of…”
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14
Different effects of two peripheral anionic site-binding ligands on acetylcholinesterase active-site gorge topography revealed by electron paramagnetic resonance
Published in Biochimica et biophysica acta, Protein structure and molecular enzymology (12-06-1995)“…Both propidium and monoclonal antibody (mAb) 25B 1 bind to the peripheral anionic site region of fetal bovine serum acetylcholinesterase (FBS AChE). Using…”
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15
lnterleukin-10 Inducing Activity of LK423, a Phthalimido-desmuramyldipeptide Compound
Published in Arzneimittel-Forschung (28-12-2011)“…Summary A new phthalimido compound, N-[2-(2-phthalimidoethoxy)acetyl]-L-alanyl-D-glutamic acid (CAS 142489-47-2, LK423), was examined along with other…”
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Therapeutic Effects of LK 423, a Phthalimido-desmuramyldipeptide Compound, on Dextran Sulfate Sodium-Induced Colitis in Rodents Through Restoring
Published in Arzneimittel-Forschung (28-12-2011)“…Summary A new phthalimido compound, N-[2-(2-phthalimidoethoxy)acetyl]-L-alanyl-D-glutamic acid (CAS 142489-47-2, LK 423), was examined for its possible…”
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On the location of active serines of membrane acetylcholinesterase studied by the ESR method
Published in Biochimica et biophysica acta (07-06-1976)“…1. An attempt was made to find out the causes of the discrepancy between the ESR spectra of membrane acetylcholinesterase (EC 3.1.1.7) obtained by Morrisett…”
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Interleukin-10 inducing activity of LK423, a phthalimido-desmuramyldipeptide compound
Published in Arzneimittel-Forschung (1999)“…A new phthalimido compound, N-[2-(2-phthalimidoethoxy)acetyl]-L-alanyl-D-glutamic acid (CAS 142489-47-2, LK423), was examined along with other…”
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Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium-induced colitis in rodents through restoring their interleukin-10 producing capacity
Published in Arzneimittel-Forschung (01-02-1999)“…A new phthalimido compound, N-[2-(2-phthalimidoethoxy)acetyl]-L-alanyl-D-glutamic acid (CAS 142489-47-2, LK 423), was examined for its possible activity to…”
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