Search Results - "Štafl, Kryštof"
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Heterologous avian system for quantitative analysis of Syncytin-1 interaction with ASCT2 receptor
Published in Retrovirology (22-06-2021)“…Human Syncytin-1 is a placentally-expressed cell surface glycoprotein of retroviral origin. After interaction with ASCT2, its cellular receptor, Syncytin-1…”
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Receptor usage of Syncytin-1: ASCT2, but not ASCT1, is a functional receptor and effector of cell fusion in the human placenta
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2024)“…Syncytin-1, a human fusogenic protein of retroviral origin, is crucial for placental syncytiotrophoblast formation. To mediate cell-to-cell fusion, Syncytin-1…”
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Retroviral host range extension is coupled with Env-activating mutations resulting in receptor-independent entry
Published in Proceedings of the National Academy of Sciences - PNAS (27-06-2017)“…The extent of virus transmission among individuals and species is generally determined by the presence of specific membrane-embedded virus receptors required…”
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