Search Results - "Štícha, M."

Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation by Kluckova, K, Sticha, M, Cerny, J, Mracek, T, Dong, L, Drahota, Z, Gottlieb, E, Neuzil, J, Rohlena, J

“…Respiratory complex II (CII, succinate dehydrogenase, SDH) inhibition can induce cell death, but the mechanistic details need clarification. To elucidate the…”
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Induction of cancer cell apoptosis by α‐tocopheryl succinate: molecular pathways and structural requirements by NEUZIL, JIRÍ, WEBER, TOBIAS, SCHRÖDER, ANDREAS, LU, MIN, OSTERMANN, GEORG, GELLERT, NINA, MAYNE, GEORGE C., OLEJNICKA, BEATA, NÈGRE‐SALVAYRE, ANNE, STÍCHA, MARTIN, COFFEY, ROBERT J., WEBER, CHRISTIAN

“…ABSTRACT The vitamin E analog α‐tocopheryl succinate (α‐TOS) can induce apoptosis. We show that the proapoptotic activity of α‐TOS in hematopoietic and cancer…”
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Synthesis and spectra of N-15 labelled phenylazides by Lešetický, L., Barth, R., Nêmec, I., Štícha, M., Tišlerová, I.

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Separation of amino acid and peptide stereoisomers by nonionic micelle-mediated capillary electrophoresis after chiral derivatization by Liu, Yi-Ming, Schneider, Michael, Sticha, Cheryl M., Toyooka, Toshimasa, Sweedler, Jonathan V.

“…Enantiomers of amino acids and peptides were derivatized with a fluorescent chiral reagent, 4-(3-isothiocyanatopyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole […”
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STRUCTURE-PROPERTY RELATIONSHIPS OF THIOACRIDINES; THEIR ELECTROCHEMICAL OXIDATION AS A MODEL OF METABOLIC DEGRADATION by Nesmerak, K., Nemec, I., Sticha, M., Nemcova, I., Horka, V.

“…The relationships of structure vs. electrochemical and vs. chromatographical properties of thirteen 9-(alkylthio)acridines were studied and quantified by…”
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Vitamin a derivatives labelled with 131I — Potential agents for liver scintigraphy by Kadeřávek, J., Kozempel, J., Štícha, M., Petrášek, J., Jirsa, M., Taimr, P., Lešetický, L.

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Mitochondria Play a Central Role in Apoptosis Induced by α-Tocopheryl Succinate, an Agent with Antineoplastic Activity:  Comparison with Receptor-Mediated Pro-Apoptotic Signaling by Weber, Tobias, Dalen, Helge, Andera, Ladislav, Nègre-Salvayre, Anne, Augé, Nathalie, Sticha, Martin, Lloret, Ana, Terman, Alexei, Witting, Paul K, Higuchi, Masahiro, Plasilova, Magdalena, Zivny, Jan, Gellert, Nina, Weber, Christian, Neuzil, Jiri

“…α-Tocopheryl succinate (α-TOS) is a semisynthetic vitamin E analogue with high pro-apoptotic and anti-neoplastic activity [Weber, T et al. (2002) Clin. Cancer…”
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Vitamin a derivatives labelled with 131I — Potential agents for liver scientigraphy by Kadeřávek, J., Kozempel, J., Štícha, M., Petrášek, J., Jirsa, M., Taimr, P., Lešetický, L.

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Enatiomeric determination of tramadol and O-desmethyltramadol in human urine by gas chromatography–mass spectrometry by Chytil, Lukáš, Štícha, Martin, Matoušková, Olga, Perlík, František, Slanař, Ondřej

“…A GC–MS assay for stereoselective determination of tramadol and its pharmacologically active phase I metabolite O-desmethyltramadol in human urine was…”
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Alpha-tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability by Neuzil, Jiri, Zhao, Ming, Ostermann, Georg, Sticha, Martin, Gellert, Nina, Weber, Christian, Eaton, John W, Brunk, Ulf T

“…Certain vitamin E analogues, such as alpha-tocopheryl succinate (alpha-TOS), exhibit in vivo anti-tumour activity and, in vitro, induce apoptosis of cultured…”
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Synthesis of N-Alkylated and N-Arylated Derivatives of 2-Amino-2‘-hydroxy-1,1‘-binaphthyl (NOBIN) and 2,2‘-Diamino-1,1‘-binaphthyl and Their Application in the Enantioselective Addition of Diethylzinc to Aromatic Aldehydes by Vyskočil, Štěpán, Jaracz, Stanislav, Smrčina, Martin, Štícha, Martin, Hanuš, Vladimír, Polášek, Miroslav, Kočovský, Pavel

“…High-yield reductive alkylation of (R)-(+)-1 and (R)-(+)-2 has been accomplished with a series of ketones (even as bulky as 2-adamantanone) and NaBH4/H2SO4 in…”
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Quantitative structure–property relationships of new benzoxazines and their electrooxidation as a model of metabolic degradation by Nesmerak, Karel, Nemec, Ivan, Sticha, Martin, Waisser, Karel, Palat, Karel

“…The quantitative structure–property relationships study of 40 benzoxazines, that seem to be very promising antimycobacterial drugs, allowed proposing and…”
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PCV41 COSTS AND LENGTH OF STAY IN PATIENTS HOSPITALIZED FOR ACUTE HEART FAILURE by Ondrackova, B, Miklik, R, Parenica, J, Spinar, J, Sticha, M

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Short communication the preparation of stable protected 3-ethynylpyrrole suitable for electrochemical polymerization by Hlavaty, J, Kubista, J, Sticha, M

“…Stable protected 3‐triisopropylsilylethynylpyrrole, 4b, was prepared in the yield 73% by first observed selective deprotection of double protected…”
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Vitamin E succinate induces apoptosis in hematopoietic and cancer cell lines: Structural requirements and role of protein kinase by Neuzil, J., Schroder, A., Weber, T., Gellert, N., Lu, M., Sticha, M., Coffey, R.J., Weber, C.

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Mitochondria play a central role in apoptosis induced by a-tocopheryl succinate, an agent with antineoplastic activity: Comparison with receptor-mediated pro-apoptotic signaling by Weber, A, Dalen, Helge, Andera, L, Nègre-Salvayre, A, Augé, N, Sticha, M, Loret, A, Terman, Alexei, Witting, PK, Higuchi, M, Plasilova, M, Zivny, J, Gellert, N, Weber, C, Neuzil, Jiri

“…a-Tocopheryl succinate (a-TOS) is a semisynthetic vitamin E analogue with high pro-apoptotic and anti-neoplastic activity [Weber, T et al. (2002) Clin. Cancer…”
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Identification and Purity Control of Thioacridine Derivatives by Gas and Capillary Liquid Chromatography with Mass Spectrometric Detection by KUTNEROVA, Blanka, JELINEK, Ivan, STICHA, Martin, NEMCOVA, Irena

“…Mass spectrometry combined with gas chromatography (GC-MS) or capillary liquid chromatography (CLC-MS) was successfully utilized for structural…”
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TARCEVA Clinical Registry by Skricková, J, Pesek, M, Zatloukal, P, Kolek, V, Salajka, F, Koubková, L, Krejcí, J, Tomísková, M, Grygárková, Y, Havel, L, Hrnciarik, M, Skalová, B, Stícha, M

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Polymerization of p-nitrophenylacetylene with metathesis catalysts. photoelectrical properties of phenylacetylene/p-nitrophenylacetylene copolymer by SEDLACEK, J, VOHLIDAL, J, CABIOCH, S, LAVASTRE, O, DIXNEUF, P, BALCAR, H, STICHA, M, PFLEGER, J, BLECHTA, V

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Induction of cancer cell apoptosis by a-tocopheryl succinate: Molecular pathways and structural requirements by Neuzil, J., Weber, T., Schroder, A., Lu, M., Ostermann, G., Gellert, N., Mayne, G.C., Olejnicka, Beata, Negre-Salvayre, A., Sticha, M., Coffey, R.J., Weber, C.

“…The vitamin E analog a-tocopheryl succinate (a-TOS) can induce apoptosis. We show that the proapoptotic activity of a-TOS in hematopoietic and cancer cell…”
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