Search Results - "Šribar, Jernej"

Combatting the antigenicity of common ragweed pollen and its primary allergen Amb a 1 with cold atmospheric pressure air plasma by Hojnik, Nataša, Shvalya, Vasyl, Zavašnik, Janez, Šribar, Jernej, Križaj, Igor, Walsh, James L.

“…Airborne allergens, especially those originating from various types of pollen, significantly compromise the health and well-being of individuals on a global…”
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Serine pseudoproteases in physiology and disease by Zupanič, Nina, Počič, Jernej, Leonardi, Adrijana, Šribar, Jernej, Kordiš, Dušan, Križaj, Igor

“…Serine proteases (SPs) constitute a very important family of enzymes, both physiologically and pathologically. The effects produced by these proteins have been…”
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Rat Group IIA Secreted Phospholipase A2 Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer’s Disease by Ivanušec, Adrijan, Šribar, Jernej, Leonardi, Adrijana, Zorović, Maja, Živin, Marko, Križaj, Igor

“…Alzheimer’s disease (AD), a progressive form of dementia, is characterized by the increased expression of secreted phospholipase A2 group IIA (GIIA) in the…”
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The Phospholipase Activity of Ammodytoxin, a Prototype Snake Venom β-Neurotoxin, Is Not Obligatory for Cell Internalisation and Translocation to Mitochondria by Ivanušec, Adrijan, Šribar, Jernej, Veranič, Peter, Križaj, Igor

“…β-Neurotoxins are secreted phospholipase A2 molecules that inhibit transmission in neuromuscular synapses by poisoning the motor neurons. These toxins…”
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The neurotoxic secreted phospholipase A2 from the Vipera a. ammodytes venom targets cytochrome c oxidase in neuronal mitochondria by Šribar, Jernej, Kovačič, Lidija, Oberčkal, Jernej, Ivanušec, Adrijan, Petan, Toni, Fox, Jay W., Križaj, Igor

“…The β-neurotoxic secreted phospholipases A 2 (sPLA 2 s) block neuro-muscular transmission by poisoning nerve terminals. Damage inflicted by such sPLA 2 s…”
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Anti-vimentin, anti-TUFM, anti-NAP1L1 and anti-DPYSL2 nanobodies display cytotoxic effect and reduce glioblastoma cell migration by Zottel, Alja, Jovčevska, Ivana, Šamec, Neja, Mlakar, Jernej, Šribar, Jernej, Križaj, Igor, Skoblar Vidmar, Marija, Komel, Radovan

“…Background: Glioblastoma is a particularly common and very aggressive primary brain tumour. One of the main causes of therapy failure is the presence of…”
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Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A2: An update by Šribar, Jernej, Oberčkal, Jernej, Križaj, Igor

“…β-neurotoxins are enzymes, secreted phospholipases A2, that inhibit neurotransmission in neuromuscular synapses by poisoning the motoneuron. They were reviewed…”
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Time‐dependent uptake and trafficking of vesicles capturing extracellular S100B in cultured rat astrocytes by Lasič, Eva, Galland, Fabiana, Vardjan, Nina, Šribar, Jernej, Križaj, Igor, Leite, Marina Concli, Zorec, Robert, Stenovec, Matjaž

“…Astrocytes, the most heterogeneous glial cells in the central nervous system, contribute to brain homeostasis, by regulating a myriad of functions, including…”
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Venomics of Vipera berus berus to explain differences in pathology elicited by Vipera ammodytes ammodytes envenomation: Therapeutic implications by Latinović, Zorica, Leonardi, Adrijana, Šribar, Jernej, Sajevic, Tamara, Žužek, Monika C., Frangež, Robert, Halassy, Beata, Trampuš-Bakija, Alenka, Pungerčar, Jože, Križaj, Igor

“…Vipera berus berus (Vbb) is the most widely distributed and Vipera ammodytes ammodytes (Vaa) the most venomous viper in Europe. In particular areas of the Old…”
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The First Intrinsic Tenase Complex Inhibitor with Serine Protease Structure Offers a New Perspective in Anticoagulant Therapy by Latinović, Zorica, Leonardi, Adrijana, Kovačič, Lidija, Koh, Cho Yeow, Šribar, Jernej, Bakija, Alenka Trampuš, Venkateswarlu, Divi, Kini, R Manjunatha, Križaj, Igor

“…Components of the intrinsic blood coagulation pathway, among them factor VIIIa (FVIIIa), have been recognized as suitable therapeutic targets to treat venous…”
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Secreted Phospholipases A2 - not just Enzymes by Sribar, Jernej, Križaj, Igor

“…Secreted phospholipases A2 (sPLA2s) constitute, physiologically and pathologically, a very important family of enzymes. Most actions of sPLA2s have been…”
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Glioblastoma-specific anti-TUFM nanobody for in-vitro immunoimaging and cancer stem cell targeting by Samec, Neja, Jovcevska, Ivana, Stojan, Jure, Zottel, Alja, Liovic, Mirjana, Myers, Michael P, Muyldermans, Serge, Šribar, Jernej, Križaj, Igor, Komel, Radovan

“…Glioblastoma multiforme (GBM) is the most common and lethal form of brain tumor. The prognosis for patients remains poor, despite the combination of new…”
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On the role of protein disulfide isomerase in the retrograde cell transport of secreted phospholipases A2 by Oberčkal, Jernej, Kovačič, Lidija, Šribar, Jernej, Leonardi, Adrijana, Dolinar, Klemen, Pucer Janež, Anja, Križaj, Igor

“…Following the finding that ammodytoxin (Atx), a neurotoxic secreted phospholipase A2 (sPLA2) in snake venom, binds specifically to protein disulfide isomerase…”
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An antibacterial macroporous polyurethane hybrid material with a high content of zinc ions: A template to uniform ZnO nanoparticles by Ambrožič, Gabriela, Šribar, Jernej, Škapin, Srečo D., Žigon, Majda, Orel, Zorica Crnjak

“…[Display omitted] ► Novel macroporous Zn-embedded polyurethane hybrid was prepared. ► The material exhibits extremely strong antibacterial properties against…”
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first phospholipase inhibitor from the serum of Vipera ammodytes ammodytes by Šribar, Jernej, Kovačič, Lidija, Draškovič, Petra, Faure, Grazyna, Križaj, Igor

“…Ammodytoxins are neurotoxic secretory phospholipase A₂ molecules, some of the most toxic components of the long-nosed viper (Vipera ammodytes ammodytes) venom…”
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Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A(2): an update by Šribar, Jernej, Oberčkal, Jernej, Križaj, Igor

“…β-neurotoxins are enzymes, secreted phospholipases A2, that inhibit neurotransmission in neuromuscular synapses by poisoning the motoneuron. They were reviewed…”
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A new photoprobe for studying biological activities of secreted phospholipases A2 by Kovacic, Lidija, Sribar, Jernej, Krizaj, Igor

“…Ammodytoxin (Atx) is a snake venom phospholipase A2 (sPLA2s) with presynaptic toxicity, anticoagulant activity and the ability to influence cell cycle…”
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The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3 protein gamma and epsilon isoforms by Sribar, Jernej, Sherman, Nicholas E, Prijatelj, Petra, Faure, Grazyna, Gubensek, Franc, Fox, Jay W, Aitken, Alastair, Pungercar, Joze, Krizaj, Igor

“…Two novel acceptors for ammodytoxin C, a presynaptically neurotoxic phospholipase A(2) from snake venom, have been purified from porcine cerebral cortex by a…”
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Secreted Phospholipases A2 - not just Enzymes: Revisited by Ivanušec, Adrijan, Šribar, Jernej, Križaj, Igor

“…Secreted phospholipases A2 (sPLA2s) participate in a very broad spectrum of biological processes through their enzymatic activity and as ligands for membrane…”
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Protein disulphide isomerase binds ammodytoxin strongly: Possible implications for toxin trafficking by Šribar, Jernej, Anderluh, Gregor, Fox, Jay W., Križaj, Igor

“…Ammodytoxin, a group IIA secreted phospholipase A 2 from the venom of the long-nosed viper ( Vipera ammodytes ammodytes), is a potent presynaptically acting…”
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