Search Results - "Šponer, Judit E"

Acid‐Catalyzed RNA‐Oligomerization from 3’,5’‐cGMP by Wunnava, Sreekar, Dirscherl, Christina F., Výravský, Jakub, Kovařík, Aleš, Matyášek, Roman, Šponer, Jiří, Braun, Dieter, Šponer, Judit E.

“…The assembly of ancient informational polymers from nucleotide precursors is the central challenge of life's origin on our planet. Among the possible…”
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Prebiotic Synthesis of 3’,5’‐Cyclic Adenosine and Guanosine Monophosphates through Carbodiimide‐Assisted Cyclization by Coulon, Rémi, Papoušková, Barbora, Mohammadi, Elmira, Otyepka, Michal, Wunnava, Sreekar, Šponer, Jiří, Šponer, Judit E.

“…3’,5’‐Cyclic nucleotides play a fundamental role in modern biochemical processes and have been suggested to have played a central role at the origin of…”
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Stereocontrolled Synthesis of (−)-Bactobolin A by Vojáčková, Petra, Michalska, Lucyna, Nečas, Marek, Shcherbakov, Dimitri, Böttger, Erik C, Šponer, Jiří, Šponer, Judit E, Švenda, Jakub

“…A stereoselective synthesis of the ribosome-binding antitumor antibiotic (−)-bactobolin A is reported. The presented approach makes effective use of (−)-quinic…”
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The DNA and RNA sugar-phosphate backbone emerges as the key player. An overview of quantum-chemical, structural biology and simulation studies by Šponer, Jiří, Mládek, Arnošt, Šponer, Judit E, Svozil, Daniel, Zgarbová, Marie, Banáš, Pavel, Jurečka, Petr, Otyepka, Michal

“…Knowledge of geometrical and physico-chemical properties of the sugar-phosphate backbone substantially contributes to the comprehension of the structural…”
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On the Road from Formamide Ices to Nucleobases: IR-Spectroscopic Observation of a Direct Reaction between Cyano Radicals and Formamide in a High-Energy Impact Event by Ferus, Martin, Civiš, Svatopluk, Mládek, Arnošt, Šponer, Jiří, Juha, Libor, Šponer, Judit E

“…The formamide-based synthesis of nucleic acids is considered as a nonaqueous scenario for the emergence of biomolecules from inorganic matter. In the current…”
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Insoluble organic matter - an “organic” cradle of life: Comment on the paper “Insoluble organic matter in chondrites: Archetypal melanin-like PAH-based multifunctionality at the origin of life?” by Marco d'Ischia et al by Šponer, Judit E., Šponer, Jiří

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Quantum Chemical Studies of Nucleic Acids: Can We Construct a Bridge to the RNA Structural Biology and Bioinformatics Communities? by Šponer, Jiří, Šponer, Judit E, Petrov, Anton I, Leontis, Neocles B

“…In this feature article, we provide a side-by-side introduction for two research fields: quantum chemical calculations of molecular interaction in nucleic…”
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Formic acid, the precursor of formamide, from serpentinization: Comment on the paper: “Mineral self-organization on a lifeless planet” by Juan Manuel García-Ruiz, Mark A. van Zuilen and Wolfgang Bach by Šponer, Judit E., Šponer, Jiří

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Untemplated Nonenzymatic Polymerization of 3′,5′cGMP: A Plausible Route to 3′,5′-Linked Oligonucleotides in Primordia by Šponer, Judit E, Šponer, Jiří, Giorgi, Alessandra, Di Mauro, Ernesto, Pino, Samanta, Costanzo, Giovanna

“…The high-energy 3′,5′ phosphodiester linkages conserved in 3′,5′ cyclic GMPs offer a genuine solution for monomer activation required by the…”
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Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context by Saladino, Raffaele, Bizzarri, Bruno M., Botta, Lorenzo, Šponer, Jiří, Šponer, Judit E., Georgelin, Thomas, Jaber, Maguy, Rigaud, Baptiste, Kapralov, Mikhail, Timoshenko, Gennady N., Rozanov, Alexei, Krasavin, Eugene, Timperio, Anna Maria, Mauro, Ernesto Di

“…The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to…”
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Prebiotic synthesis at impact craters: the role of Fe-clays and iron meteorites by Pastorek, Adam, Hrnčířová, Jana, Jankovič, Luboš, Nejdl, Lukáš, Civiš, Svatopluk, Ivanek, Ondřej, Shestivska, Violetta, KníŽek, Antonín, Kubelík, Petr, Šponer, Jiří, Petera, Lukáš, Křivková, Anna, Cassone, Giuseppe, Vaculovičová, Markéta, Šponer, Judit E, Ferus, Martin

“…Besides delivering plausible prebiotic feedstock molecules and high-energy initiators, extraterrestrial impacts could also affect the process of abiogenesis by…”
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Phosphoric acid salts of amino acids as a source of oligopeptides on the early Earth by Šponer, Judit E., Coulon, Rémi, Otyepka, Michal, Šponer, Jiří, Siegle, Alexander F., Trapp, Oliver, Ślepokura, Katarzyna, Zdráhal, Zbyněk, Šedo, Ondrej

“…Because of their unique proton-conductivity, chains of phosphoric acid molecules are excellent proton-transfer catalysts. Here we demonstrate that this…”
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RNA Oligomerisation without Added Catalyst from 2′,3′‐Cyclic Nucleotides by Drying at Air‐Water Interfaces by Dass, Avinash Vicholous, Wunnava, Sreekar, Langlais, Juliette, Esch, Beatriz, Krusche, Maik, Ufer, Lennard, Chrisam, Nico, Dubini, Romeo C. A., Gartner, Florian, Angerpointner, Severin, Dirscherl, Christina F., Rovó, Petra, Mast, Christof B., Šponer, Judit E., Ochsenfeld, Christian, Frey, Erwin, Braun, Dieter

“…For the emergence of life, the abiotic synthesis of RNA from its monomers is a central step. We found that in alkaline, drying conditions in bulk and at heated…”
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How to understand quantum chemical computations on DNA and RNA systems? A practical guide for non-specialists by Šponer, Jiří, Šponer, Judit E., Mládek, Arnošt, Banáš, Pavel, Jurečka, Petr, Otyepka, Michal

“…•Applications of modern quantum chemical (QM) methods to nucleic acids are explained.•Prospect of large-scale QM calculations of nucleic acids is…”
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Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context by Šponer, Judit E., Šponer, Jiří, Výravský, Jakub, Matyášek, Roman, Kovařík, Aleš, Dudziak, Wojciech, Ślepokura, Katarzyna

“…Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet. In the…”
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Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3',5' Cyclic Nucleotide Precursors by Šponer, Judit E, Šponer, Jiří, Kovařík, Aleš, Šedo, Ondrej, Zdráhal, Zbyněk, Costanzo, Giovanna, Di Mauro, Ernesto

“…Template-free nonenzymatic polymerization of 3',5' cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of…”
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Theoretical studies of the mechanism of 2-aminooxazole formation under prebiotically plausible conditions by Szabla, Rafał, Šponer, Judit E, Šponer, Jiří, Góra, Robert W

“…2-Aminooxazole is generally considered to play a central role in the origin of informational polymers. In the current contribution we use density functional…”
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Sustainability and Chaos in the Abiotic Polymerization of 3’,5’ Cyclic Guanosine Monophosphate: The Role of Aggregation by Costanzo, Giovanna, Šponer, Judit E., Šponer, Jiří, Cirigliano, Angela, Benedetti, Piero, Giliberti, Valeria, Polito, Raffaella, Di Mauro, Ernesto

“…The front cover artwork is provided by Judit Šponer (Institute of Biophysics, Czech Academy of Sciences). The image shows that polymerization of H‐form 3’,5’…”
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Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA by Saladino, Raffaele, Šponer, Judit E, Šponer, Jiří, Costanzo, Giovanna, Pino, Samanta, Di Mauro, Ernesto

“…Molecular Darwinian evolution is an intrinsic property of reacting pools of molecules resulting in the adaptation of the system to changing conditions. It has…”
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Room temperature spontaneous conversion of OCS to CO2 on the anatase TiO2 surface by Civiš, Svatopluk, Ferus, Martin, Šponer, Judit E, Šponer, Jirí, Kavan, Ladislav, Zukalová, Markéta

“…High-resolution FT-IR spectroscopy combined with quantum chemical calculations was used to study the chemistry of OCS-disproportionation over the reduced…”
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