Search Results - "Šmatlíková, Petra"

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    Transgenic minipig model of Huntington's disease exhibiting gradually progressing neurodegeneration by Ardan, Taras, Baxa, Monika, Levinská, Božena, Sedláčková, Miroslava, Nguyen, The Duong, Klíma, Jiří, Juhás, Štefan, Juhásová, Jana, Šmatlíková, Petra, Vochozková, Petra, Motlík, Jan, Ellederová, Zdenka

    Published in Disease models & mechanisms (01-02-2020)
    “…Recently developed therapeutic approaches for the treatment of Huntington's disease (HD) require preclinical testing in large animal models. The minipig is a…”
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    Journal Article
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    A36 Gradual accumulation of oxidative stress and its aspects in primary porcine fibroblasts expressing mutated huntingtin by Smatlikova, Petra, Askeland, Georgina, Vaskovicova, Michaela, Klima, Jiri, Motlik, Jan, Eide, Lars, Ellederova, Zdenka

    “…BackgroundHuntington´s disease (HD) is devastating neurodegenerative disorder caused by the mutation in huntingtin gene. One of the largest contributors to HD…”
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    Journal Article
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    Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells in Pig Transgenic Model Expressing Human Mutant Huntingtin by Smatlikova, Petra, Juhas, Stefan, Juhasova, Jana, Suchy, Tomas, Hubalek Kalbacova, Marie, Ellederova, Zdenka, Motlik, Jan, Klima, Jiri

    Published in Journal of Huntington's disease (01-01-2019)
    “…Although the highest expression of mutant huntingtin (mtHtt) was observed in the brain, its negative effects were also apparent in other tissues. Specifically,…”
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    Journal Article