Search Results - "Šmarda, Jan"

Trop2: Jack of All Trades, Master of None by Lenart, Sara, Lenart, Peter, Smarda, Jan, Remsik, Jan, Soucek, Karel, Benes, Petr

“…Trophoblast cell surface antigen 2 (Trop2) is a widely expressed glycoprotein and an epithelial cell adhesion molecule (EpCAM) family member. Although…”
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Synergistic cytotoxicity of perifosine and ABT‐737 to colon cancer cells by Adamová, Barbora, Říhová, Kamila, Pokludová, Jana, Beneš, Petr, Šmarda, Jan, Navrátilová, Jarmila

“…An acidic environment and hypoxia within the tumour are hallmarks of cancer that contribute to cell resistance to therapy. Deregulation of the PI3K/Akt pathway…”
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Low-Glucose Conditions of Tumor Microenvironment Enhance Cytotoxicity of Tetrathiomolybdate to Neuroblastoma Cells by Navrátilová, Jarmila, Hankeová, Tereza, Beneš, Petr, Smarda, Jan

“…Growth of tumor cells depends on sufficient supply of fermentable substrate, such as glucose. This provokes development of new anticancer therapies based on…”
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Novel Colicin FY of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation by BOSAK, Juraj, LAIBLOVA, Petra, SMARDA, Jan, DEDICOVA, Daniela, SMAJS, David

“…A novel colicin type, designated colicin FY, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin FY was active against…”
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Acidic pH of tumor microenvironment enhances cytotoxicity of the disulfiram/Cu2+ complex to breast and colon cancer cells by Navrátilová, Jarmila, Hankeová, Tereza, Beneš, Petr, Šmarda, Jan

“…Resistance of cancer cells to chemotherapeutic agents is a major cause of treatment failure in patients with cancer. The drug resistance of tumor cells can be…”
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Novel Colicin F Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation by Bosák, Juraj, Laiblová, Petra, Šmarda, Jan, Dědičová, Daniela, Šmajs, David

“…A novel colicin type, designated colicin F Y , was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F Y was active against…”
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Phage Tail-Like (High-Molecular-Weight) Bacteriocins of Budvicia aquatica and Pragia fontium (Enterobacteriaceae) by SMARDA, Jan, BENADA, Oldrich

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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MALDI MS Imaging at Acquisition Rates Exceeding 100 Pixels per Second by Bednařík, Antonín, Machálková, Markéta, Moskovets, Eugene, Coufalíková, Kateřina, Krásenský, Pavel, Houška, Pavel, Kroupa, Jiří, Navrátilová, Jarmila, Šmarda, Jan, Preisler, Jan

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Comparison of the low-frequency magnetic field effects on bacteria Escherichia coli, Leclercia adecarboxylata and Staphylococcus aureus by Fojt, Lukáš, Strašák, Luděk, Vetterl, Vladimı́r, Šmarda, Jan

“…This work studies biological effects of low-frequency electromagnetic fields. We have exposed three different bacterial strains— Escherichia coli, Leclercia…”
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Growth/differentiation factor-15 inhibits differentiation into osteoclasts—A novel factor involved in control of osteoclast differentiation by Vaňhara, Petr, Lincová, Eva, Kozubík, Alois, Jurdic, Pierre, Souček, Karel, Šmarda, Jan

“…Survival and capability of cancer cells to form metastases fundamentally depend on interactions with their microenvironment. Secondary tumors originating from…”
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The use of Cox-2 and PPARγ signaling in anti-cancer therapies by Knopfová, Lucia, Smarda, Jan

“…Increased production of the pro-inflammatory enzyme cyclooxygenase-2 (Cox-2) and altered expression and activity of peroxisome proliferator-activated receptor…”
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Effects of low-frequency magnetic fields on bacteria Escherichia coli by Strašák, Ludek, Vetterl, Vladimı́r, Šmarda, Jan

“…The effects of low-frequency magnetic fields (Bm=2.7–10 mT, f=50 Hz, time of exposure t=0–12 min, laboratory temperature) on the viability and oxidoreductive…”
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Caspase‑9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics by Říhová, Kamila, Lapčík, Petr, Veselá, Barbora, Knopfová, Lucia, Potěšil, David, Pokludová, Jana, Šmarda, Jan, Matalová, Eva, Bouchal, Pavel, Beneš, Petr

“…Caspase-9 is traditionally considered the initiator caspase of the intrinsic apoptotic pathway. In the past decade, however, other functions beyond…”
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Functional analysis of p53 tumor suppressor in yeast by Smardová, Jana, Smarda, Jan, Koptíková, Jana

“…The p53 tumor suppressor protein is a transcription factor that mediates the cell's response to various kinds of stress by preventing cell division and/or…”
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Drug Penetration Analysis in 3D Cell Cultures Using Fiducial-Based Semiautomatic Coregistration of MALDI MSI and Immunofluorescence Images by Machálková, Markéta, Pavlatovská, Barbora, Michálek, Jan, Pruška, Adam, Štěpka, Karel, Nečasová, Tereza, Radaszkiewicz, Katarzyna Anna, Kozubek, Michal, Šmarda, Jan, Preisler, Jan, Navrátilová, Jarmila

“…In this paper, we present an easy-to-follow procedure for the analysis of tissue sections from 3D cell cultures (spheroids) by matrix-assisted laser…”
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Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis by Ondrouskova, Eva, Soucek, Karel, Horvath, Viktor, Smarda, Jan

“…Abstract Loss of programmed cell death pathways is one of the features of malignancy that complicate the response of cancer cells to a therapy. Activation of…”
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c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells by Dúcka, Monika, Kučeríková, Martina, Trčka, Filip, Červinka, Jakub, Biglieri, Elisabetta, Šmarda, Jan, Borsig, Lubor, Beneš, Petr, Knopfová, Lucia

“…•c-Myb attenuates NF-κB activity in breast cancer.•Interaction with co-activator p300 is required for NF-κB suppression by c-Myb.•c-Myb negatively regulates…”
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Plant coumestans: recent advances and future perspectives in cancer therapy by Nehybová, Tereza, Šmarda, Jan, Beneš, Petr

“…Natural products are often used in drug development due to their ability to form unique and diverse chemical structures. Coumestans are polycyclic aromatic…”
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TACSTD2 upregulation is an early reaction to lung infection by Lenárt, Sára, Lenárt, Peter, Knopfová, Lucia, Kotasová, Hana, Pelková, Vendula, Sedláková, Veronika, Vacek, Ondřej, Pokludová, Jana, Čan, Vladimír, Šmarda, Jan, Souček, Karel, Hampl, Aleš, Beneš, Petr

“…TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first…”
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Disulfiram increases the efficacy of 5-fluorouracil in organotypic cultures of colorectal carcinoma by Hendrych, Michal, Říhová, Kamila, Adamová, Barbora, Hradil, Vojtěch, Stiborek, Marek, Vlček, Petr, Hermanová, Markéta, Vašíčková, Jana, Beneš, Petr, Šmarda, Jan, Kanický, Viktor, Preisler, Jan, Navrátilová, Jarmila

“…Drug efficacy determined in preclinical research is difficult to transfer to clinical practice. This is mainly due to the use of oversimplified models omitting…”
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