Search Results - "Škop, V"

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    Dissecting the role of Folr1 and Folh1 genes in the pathogenesis of metabolic syndrome in spontaneously hypertensive rats by Šilhavý, J, Krijt, J, Sokolová, J, Zídek, V, Mlejnek, P, Šimáková, M, Škop, V, Trnovská, J, Oliyarnyk, O, Marková, I, Hüttl, M, Malínská, H, Kazdová, L, Liška, F, Kožich, V, Pravenec, M

    Published in Physiological research (01-01-2018)
    “…Increased levels of plasma cysteine predispose to obesity and metabolic disturbances. Our recent genetic analyses in spontaneously hypertensive rats (SHR)…”
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    Journal Article
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    Metformin attenuates myocardium dicarbonyl stress induced by chronic hypertriglyceridemia by Malinska, H, Škop, V, Trnovska, J, Markova, I, Svoboda, P, Kazdova, L, Haluzik, M

    Published in Physiological research (01-01-2018)
    “…Reactive dicarbonyls stimulate production of advanced glycation endproducts, increase oxidative stress and inflammation and contribute to the development of…”
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    Autophagy-lysosomal pathway is involved in lipid degradation in rat liver by Skop, V, Cahová, M, Papáčková, Z, Páleníčková, E, Daňková, H, Baranowski, M, Zabielski, P, Zdychová, J, Zídková, J, Kazdová, L

    Published in Physiological research (01-01-2012)
    “…We present data supporting the hypothesis that the lysosomal-autophagy pathway is involved in the degradation of intracellular triacylglycerols in the liver…”
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    Visfatin is actively secreted in vitro from U-937 macrophages, but only passively released from 3T3-L1 adipocytes and HepG2 hepatocytes by Svoboda, P, KříŽová, E, Čeňková, K, Vápenková, K, Zídková, J, Zídek, V, Škop, V

    Published in Physiological research (01-01-2017)
    “…Visfatin is a multi-functional molecule that can act intracellularly and extracellularly as an adipokine, cytokine and enzyme. One of the main questions…”
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    Hepatotoxic effects of fenofibrate in spontaneously hypertensive rats expressing human C-reactive protein by Škop, V, Trnovská, J, Oliyarnyk, O, Marková, I, Malínská, H, Kazdová, L, Zídek, V, Landa, V, Mlejnek, P, Šimáková, M, Kůdela, M, Pravenec, M, Šilhavý, J

    Published in Physiological research (01-01-2016)
    “…Dyslipidemia and inflammation play an important role in the pathogenesis of cardiovascular and liver disease. Fenofibrate has a well-known efficacy to reduce…”
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    Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity by Pravenec, M, Zídek, V, Landa, V, Mlejnek, P, Šilhavý, J, Šimáková, M, Trnovská, J, Škop, V, Marková, I, Malínská, H, Hüttl, M, Kazdová, L, Bardová, K, Tauchmannová, K, Vrbacký, M, Nůsková, H, Mráček, T, Kopecký, J, Houštěk, J

    Published in Physiological research (01-01-2017)
    “…Brown adipose tissue (BAT) plays an important role in lipid and glucose metabolism in rodents and possibly also in humans. Identification of genes responsible…”
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    Autocrine effects of visfatin on hepatocyte sensitivity to insulin action by Skop, V, Kontrová, K, Zídek, V, Pravenec, M, Kazdová, L, Mikulík, K, Sajdok, J, Zídková, J

    Published in Physiological research (01-01-2010)
    “…Visfatin was originally described as an adipokine with insulin mimetic effects. Recently, it was found that visfatin is identical with the Nampt (nicotinamide…”
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    Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat by Trnovská, J, Šilhavý, J, Zídek, V, Šimáková, M, Mlejnek, P, Landa, V, Eigner, S, Eigner Henke, K, Škop, V, Oliyarnyk, O, Kazdová, L, Mráček, T, Houštěk, J, Pravenec, M

    Published in Physiological research (01-01-2015)
    “…Cold exposure of rats leads to ameliorated glucose and triglyceride utilization with females displaying better adaptation to a cold environment. In the current…”
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    CD36 regulates fatty acid composition and sensitivity to insulin in 3T3-L1 adipocytes by Kontrová, K, Zídková, J, Bartos, B, Skop, V, Sajdok, J, Kazdová, L, Mikulík, K, Mlejnek, P, Zídek, V, Pravenec, M

    Published in Physiological research (01-01-2007)
    “…In the current study, we tested a hypothesis that CD36 fatty acid (FA) transporter might affect insulin sensitivity by indirect effects on FA composition of…”
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