Search Results - "Šinkorová, Zuzana"
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Cytokines and radiation-induced pulmonary injuries
Published in Journal of radiation research (01-11-2018)“…Radiation therapy is one of the most common treatment strategies for thorax malignancies. One of the considerable limitations of this therapy is its toxicity…”
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Hyaluronic Acid Nanoparticles with Parameters Required for In Vivo Applications: From Synthesis to Parametrization
Published in Biomacromolecules (12-08-2024)“…Hyaluronic acid is an excellent biocompatible material for in vivo applications. Its ability to bind CD44, a cell receptor involved in numerous biological…”
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3
Radioreparative Effect of Diode Laser on Leukopoiesis Recovery: A Pilot Study
Published in Life (Basel, Switzerland) (01-01-2024)“…The aim of the present study was to investigate the effect of laser therapy on leukopoiesis recovery after irradiation with ionizing radiation. A dose of…”
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4
Simple, fast, cost‐efficient, reliable, and highly automated DNA content analysis of cells in adherent cultures
Published in Cytometry. Part A (01-06-2024)“…The most commonly used flow cytometric (FCM) analysis of cellular DNA content relies on ethanol fixation followed by RNA digestion and propidium iodide (PI)…”
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5
The Role of Adjuvant Radiotherapy in the Treatment of Breast Cancer
Published in Current oncology (Toronto) (24-02-2024)“…The role of postmastectomy radiotherapy and regional nodal irradiation after radical mastectomy is defined in high-risk patients with locally advanced tumors,…”
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6
Hyaluronic Acid: Known for Almost a Century, but Still in Vogue
Published in Pharmaceutics (11-04-2022)“…Hyaluronic acid (HA) has a special position among glycosaminoglycans. As a major component of the extracellular matrix (ECM). This simple, unbranched…”
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Electrochemical detection of 8-hydroxyguanine using screen-printed carbon electrodes modified with carboxy-functionalized multi-walled carbon nanotubes
Published in Monatshefte für Chemie (01-07-2019)“…The paper presents the findings of an optimization and validation results of electrochemical detection of 8-hydroxyguanine, a major marker of oxidative stress,…”
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BIOLOGICAL EFFECTS OF LOW-DOSE RADIATION FROM CT IMAGING
Published in Radiation protection dosimetry (22-08-2022)“…Abstract The dramatic rise in diagnostic procedures, radioisotope-based scans and intervention procedures has created a very valid concern regarding the…”
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NEW EXPERIMENTAL APPROACH IN BIODOSIMETRY: EX VIVO APOPTOSIS DETECTION
Published in Radiation protection dosimetry (22-08-2022)“…Abstract This study establishes a new experimental approach for retrospective biodosimetric assessment by apoptosis detection ex vivo. For this purpose, we…”
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CHANGES IN BLOOD COUNT AND LYMPHOCYTE MICRONUCLEI IN PIGLETS AFTER WHOLE-BODY IRRADIATION
Published in Radiation protection dosimetry (31-12-2019)“…Biodosimetry is focused on effects of ionizing radiation at cellular and molecular levels of living organisms so that a qualified retrospective estimate of…”
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The first in vivo multiparametric comparison of different radiation exposure biomarkers in human blood
Published in PloS one (23-02-2018)“…The increasing risk of acute large-scale radiological/nuclear exposures of population underlines the necessity of developing new, rapid and high throughput…”
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12
MITOCHONDRIA IN BIODOSIMETRY: FLOW CYTOMETRY ASSESMENT IN VITRO
Published in Radiation protection dosimetry (22-08-2022)“…Abstract The JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health. The probe was tested in vitro on two established cell lines and…”
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13
Attenuation of Radiation-Induced Lung Injury by Hyaluronic Acid Nanoparticles
Published in Frontiers in pharmacology (12-08-2020)“…Therapeutic thorax irradiation as an intervention in lung cancer has its limitations due to toxic effects leading to pneumonitis and/or pulmonary fibrosis. It…”
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14
The peripheral chimerism of bone marrow–derived stem cells after transplantation: regeneration of gastrointestinal tissues in lethally irradiated mice
Published in Journal of cellular and molecular medicine (01-05-2014)“…Bone marrow–derived cells represent a heterogeneous cell population containing haematopoietic stem and progenitor cells. These cells have been identified as…”
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Special Techniques of Adjuvant Breast Carcinoma Radiotherapy
Published in Cancers (31-12-2022)“…Modern radiotherapy techniques are designed to permit reduced irradiation of healthy tissue, resulting in a diminished risk of adverse effects and shortened…”
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16
The toxic effect of cytostatics on primary cilia frequency and multiciliation
Published in Journal of cellular and molecular medicine (01-08-2019)“…The primary cilium is considered as a key component of morphological cellular stability. However, cancer cells are notorious for lacking primary cilia in most…”
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IN VIVO BIODOSIMETRY OF PORCINE T-LYMPHOCYTE SUBSETS AND NK CELLS
Published in Radiation protection dosimetry (31-12-2019)“…The aim of the present study was to evaluate the biodosimetric potential of peripheral blood lymphocytes, particularly of T-cell subsets (null and T helper)…”
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18
Substituted Piperazines as Novel Potential Radioprotective Agents
Published in Molecules (Basel, Switzerland) (25-01-2020)“…The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine…”
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19
A study on the distribution of 85Sr and 134Cs radionuclides after total body irradiation
Published in Nuclear technology & radiation protection (2020)“…The kinetics of strontium, 85Sr, and cesium, 134Cs, were evaluated in a mouse experimental model to determine the impact of these radionuclides on a living…”
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INVESTIGATION OF THE RADIOPROTECTIVE EFFECT OF ORTHOVANADATE IN MICE AFTER TOTAL BODY IRRADIATION
Published in Radiation protection dosimetry (31-12-2019)“…The increasing risk of acute large-scale exposure of ionising irradiation on the population underlines the necessity of developing effective radioprotective…”
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