Search Results - "Šestáková, Šárka"

DNA Methylation Validation Methods: a Coherent Review with Practical Comparison by Sestáková, Sárka, Sálek, Cyril, RemeÅ¡ová, Hana

“…Here, we present a practical overview of four commonly used validation methods for DNA methylation assessment: methylation specific restriction endonucleases…”
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MethScore as a new comprehensive DNA methylation-based value refining the prognosis in acute myeloid leukemia by Šestáková, Šárka, Šálek, Cyril, Kundrát, Dávid, Cerovská, Ela, Vydra, Jan, Ježíšková, Ivana, Folta, Adam, Mayer, Jiří, Cetkovský, Petr, Remešová, Hana

“…Changes in DNA methylation are common events in the pathogenesis of acute myeloid leukemia (AML) and have been repeatedly reported as associated with…”
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ABC transporters are predictors of treatment failure in acute myeloid leukaemia by Cerovska, Ela, Salek, Cyril, Kundrat, David, Sestakova, Sarka, Pesek, Adam, Brozinova, Ivana, Belickova, Monika, Remesova, Hana

“…To date, no chemoresistance predictors are included in acute myeloid leukaemia (AML) prognostic scoring systems to distinguish responding and refractory AML…”
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A validation study of potential prognostic DNA methylation biomarkers in patients with acute myeloid leukemia using a custom DNA methylation sequencing panel by Šestáková, Šárka, Cerovská, Ela, Šálek, Cyril, Kundrát, Dávid, Ježíšková, Ivana, Folta, Adam, Mayer, Jiří, Ráčil, Zdeněk, Cetkovský, Petr, Remešová, Hana

“…Multiple studies have reported the prognostic impact of DNA methylation changes in acute myeloid leukemia (AML). However, these epigenetic markers have not…”
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WT1 Expression in Peripheral Blood at Diagnosis and During the Course of Early Consolidation Treatment Correlates With Survival in Patients With Intermediate and Poor-Risk Acute Myeloid Leukemia by Šálek, Cyril, Vydra, Jan, Cerovská, Ela, Šestáková, Šárka, Ransdorfová, Šárka, Válková, Veronika, Cetkovský, Petr, Remešová, Hana

“…Up to 55% of non-APL acute myeloid leukemias (AML) lack a molecular target suitable for standardized disease monitoring. We aimed to evaluate the prognostic…”
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Methscore As a New Prognostic Tool for Complex DNA Methylation Changes Assessment in Patients with Acute Myeloid Leukemia by Sestakova, Sarka, Šálek, Cyril, Kundrát, Dávid, Ježíšková, Ivana, Mayer, Jiří, Ráčil, Zdeněk, Cetkovský, Petr, Remešová, Hana

“…Changes in DNA methylation are characteristic for patients with acute myeloid leukemia (AML) and many studies have reported the prognostic significance of…”
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Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle–dependent in mammalian cells, and its inhibition slows cell growth by Svoboda, Petr, Krizova, Edita, Sestakova, Sarka, Vapenkova, Kamila, Knejzlik, Zdenek, Rimpelova, Silvie, Rayova, Diana, Volfova, Nikol, Krizova, Ivana, Rumlova, Michaela, Sykora, David, Kizek, Rene, Haluzik, Martin, Zidek, Vaclav, Zidkova, Jarmila, Skop, Vojtech

“…Nicotinamide phosphoribosyltransferase (NAMPT) is located in both the nucleus and cytoplasm and has multiple biological functions including catalyzing the…”
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