Search Results - "Şahin, Leyla"
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Limited Exposure to Social Isolation does not Affect the Spike Frequency and Amplitude of Penicillin-induced Epileptiform Activity in Adolescent Rats
Published in Archives of Epilepsy (01-03-2024)“…Objective: It is known that the stress experienced during this period increases the risk of seizures. This study, it was investigated the effect of limited…”
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An exploration of primary school teachers' perspectives on children's rights
Published in Behavioral sciences & the law (01-07-2024)“…This study endeavors to scrutinize the perspectives of primary school teachers regarding children's rights. Employing qualitative research methods,…”
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First-Trimester Exposure to Gadolinium-based Contrast Agents: A Utilization Study of 4.6 Million U.S. Pregnancies
Published in Radiology (01-10-2019)“…BackgroundThe safety of gadolinium-based contrast agent (GBCA) exposure during pregnancy has not been established, and the use of GBCAs during pregnancy is not…”
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Collaboration in Regulatory Science to Facilitate Therapeutic Development for Pregnant Women
Published in Current pharmaceutical design (01-01-2019)“…Therapeutic tragedies of the past, ethical concerns, and legal risks, among other factors have led to a conservative approach to clinical research during…”
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Environmental enrichment as a strategy: Attenuates the anxiety and memory impairment in social isolation stress
Published in International journal of developmental neuroscience (01-10-2022)“…Background Social isolation (SI) early in life produces behavioral and cognitive abnormalities. On the contrary, environmental enrichment (EE) offers…”
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Enrolling Pregnant Women: Issues in Clinical Research
Published in Women's health issues (01-01-2013)“…Abstract Background Despite the fact that many pregnant women are affected by a range of serious health conditions and take medications for these conditions,…”
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Clinical care for opioid-using pregnant and postpartum women: the role of obstetric providers
Published in American journal of obstetrics and gynecology (01-04-2014)“…We review clinical care issues that are related to illicit and therapeutic opioid use among pregnant women and women in the postpartum period and outline the…”
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The effects of long-term sleep deprivation on the long-term potentiation in the dentate gyrus and brain oxidation status in rats
Published in Neuroscience research (01-05-2011)“…► The effect of sleep deprivation on synaptic plasticity was studied in hippocampus. ► The antioxidant defense was diminished with no change in corticosterone…”
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Developing a systematic approach to safer medication use during pregnancy: summary of a Centers for Disease Control and Prevention–convened meeting
Published in American journal of obstetrics and gynecology (01-09-2014)“…To address information gaps that limit informed clinical decisions on medication use in pregnancy, the Centers for Disease Control and Prevention (CDC)…”
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Selenium-mediated cardioprotection against adriamycin-induced mitochondrial damage
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-04-2011)“…Adriamycin (ADR) causes morphological and functional alterations in mitochondrial structure in the heart. The study′s aim was to determine whether there is a…”
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Electrophysiological evidence of biphasic action of carnosine on long-term potentiation in urethane-anesthetized rats
Published in Neuropeptides (Edinburgh) (01-02-2011)“…Abstract Carnosine is a dipeptide synthesized by the carnosine synthetase from β-alanine and l -histidine. The well-known effects of carnosine may be related…”
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A review of pregnancy and lactation postmarketing studies required by the FDA
Published in Pharmacoepidemiology and drug safety (01-03-2023)“…Since pregnant and lactating women have historically been excluded from drug development trials, safety studies need to be conducted postapproval. This study…”
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Associations of apelin, leptin, irisin, ghrelin, insulin, glucose levels, and lipid parameters with physical activity during eight weeks of regular exercise training
Published in Archives of physiology and biochemistry (04-07-2021)“…This study aims to evaluate the effects of 8 weeks of basketball training on apelin, leptin, irisin, ghrelin, insulin, glucose, and blood lipids among…”
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The Effect of Long Term Moderate Exercise on Depressive / Anxiety-Like Behavior in Rats with Acute REM Sleep Deprivation
Published in Turkish journal of agriculture : food science and technology (01-10-2018)“…Sleep is a physiological process that influenced by internal and external factors and brain is as active as waking in certain periods. REM sleep is…”
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A Comparison of FDA and EMA Pregnancy and Lactation Labeling
Published in Clinical pharmacology and therapeutics (01-06-2023)“…The US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have robust collaboration and dialogue around the need for data and the…”
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Maternal separation increased memory function and anxiety without effects of environmental enrichment in male rats
Published in Behavioural brain research (12-03-2023)“…Maternal separation is a detrimental postnatal influence, whereas environmental enrichment is a therapeutic and protective agent. It is unclear if long-term…”
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Long term treadmill exercise performed to chronic social isolated rats regulate anxiety behavior without improving learning
Published in Life sciences (1973) (01-05-2018)“…The type and duration of exposure to stress is an important influence on emotional and cognitive functions. Learning is the adaptive response of the central…”
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Inclusion of Pregnant or Lactating Individuals in Industry-Funded Clinical Trials
Published in American journal of obstetrics and gynecology (14-11-2024)Get full text
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Chronic caffeine consumption improves the acute sleep deprivation‐induced spatial memory impairment while altering N‐methyl‐D‐aspartate receptor subunit expression in male rats
Published in International journal of developmental neuroscience (01-11-2022)“…Caffeine is a psychostimulant substance that is mostly used to prevent fatigue, increase alertness, and ameliorate sleep loss situations. In this study, we…”
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