Search Results - "ŞAHİNTÜRK, SERDAR"
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Irisin relaxes rat thoracic aorta through inhibiting signaling pathways implicatingprotein kinase C
Published in Turkish journal of medical sciences (01-01-2022)Get full text
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Metformin relaxes rat thoracic aorta via nitric oxide, AMPK, potassium channels, and PKC
Published in Iranian journal of basic medical sciences (01-09-2023)“…Objective(s): The present research aimed to identify the functional effects and underlying mechanisms of metformin on the rat thoracic aorta. Materials and…”
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3
Genomic and phenotypic delineation of congenital microcephaly
Published in Genetics in medicine (01-03-2019)“…Purpose Congenital microcephaly (CM) is an important birth defect with long term neurological sequelae. We aimed to perform detailed phenotypic and genomic…”
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Apelinerjik Sistem ve Miyokardiyal Kontraktilite
Published in T.C. Uludağ Üniversitesi Tıp Fakültesi dergisi (01-04-2020)“…Apelinerjik sistem APJ (apelin reseptörü), apelin ve elabeladan oluşmaktadır. APJ, G protein kenetli bir reseptördür. Apelin ve elabela APJ’nin endojen…”
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5
Elabela relaxes rat pulmonary artery and trachea via BKCa, KV, and KATP channels
Published in Prostaglandins & other lipid mediators (01-08-2023)“…Elabela is a newly discovered peptide hormone. This study aimed to determine the functional effects and mechanisms of action of elabela in rat pulmonary artery…”
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Cilostazol induces vasorelaxation through the activation of the eNOS/NO/cGMP pathway, prostanoids, AMPK, PKC, potassium channels, and calcium channels
Published in Prostaglandins & other lipid mediators (01-12-2023)“…This study aimed to investigate vasoactive effect mechanisms of cilostazol in rat thoracic aorta. The vessel rings prepared from the thoracic aortas of the…”
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Sıçanlarda Vasküler Tonusun Düzenlenmesinde Potasyum Kanallarının Rolünün İncelenmesi
Published in T.C. Uludağ Üniversitesi Tıp Fakültesi dergisi (30-12-2022)“…Potasyum (K+) kanalları vasküler tonusun önemli düzenleyicileridir. Bu çalışmada K+ kanal tiplerinin fenilefrin ile uyarılan vasküler tonus üzerindeki…”
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Elabela relaxes rat pulmonary artery and trachea via BK Ca , K V , and K ATP channels
Published in Prostaglandins & other lipid mediators (01-08-2023)“…Elabela is a newly discovered peptide hormone. This study aimed to determine the functional effects and mechanisms of action of elabela in rat pulmonary artery…”
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Bazal Vasküler Tonusun Düzenlenmesinde Rol Alan Mekanizmaların Sıçan Torasik Aort Modelinde İncelenmesi
Published in T.C. Uludağ Üniversitesi Tıp Fakültesi dergisi (01-12-2021)“…Bu çalışmada, endotelyal nitrik oksit sentaz (eNOS)/nitrik oksit (NO), siklooksijenaz (COX), AMP ile aktive olan protein kinaz (AMPK), mitojen ile aktive…”
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10
The role of potassium channels on vasorelaxant effects of elabela in rat thoracic aorta
Published in Türk göğüs kalp damar cerrahisi dergisi (01-01-2022)“…This study aims to investigate the roles of potassium channel subtypes in the vasorelaxant effect mechanism of elabela, which is a recently discovered…”
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11
Physiological role of K+ channels in irisin-induced vasodilation in rat thoracic aorta
Published in Peptides (New York, N.Y. : 1980) (01-01-2022)“…[Display omitted] •Irisin dilated both endothelium-intact and -denuded rat thoracic aortas pre-contracted with PHE or KCl.•Irisin induces vasodilation via KV,…”
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Vascular Functional Effect Mechanisms of Elabela in Rat Thoracic Aorta
Published in Annals of vascular surgery (01-08-2022)“…Elabela is a recently discovered peptide hormone. The present study aims to investigate the vasorelaxant effect mechanisms of elabela in the rat thoracic…”
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Irisin relaxes rat thoracic aorta: MEK1/2 signaling pathway, K V channels, SK Ca channels, and BK Ca channels are involved in irisin-induced vasodilation
Published in Canadian journal of physiology and pharmacology (01-05-2022)“…This study investigated the effects of irisin on vascular smooth muscle contractility in rat thoracic aorta, and the hypothesis that mitogen-activated protein…”
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Irisin relaxes rat thoracic aorta through inhibiting signaling pathways implicating protein kinase C
Published in Turkish journal of medical sciences (01-04-2022)“…Irisin, a newly identified exercise-derived myokine, has been found involved in a peripheral vasodilator effect. However, little is known regarding the…”
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Modulation of Melatonin Receptors Regulates Reproductive Physiology: The Impact of Agomelatine on the Estrus Cycle, Gestation, Offspring, and Uterine Contractions in Rats
Published in Physiological research (31-12-2023)“…Agomelatine is a pharmaceutical compound that functions as an agonist for melatonin receptors, with a particular affinity for the MT1 and MT2 receptor…”
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Endojen Apelin reseptör ligandlarının vasküler Kontraktiliteye Etkisi Ve olası Etki mekanizmalarının araştırılması
Published 01-01-2021“…Apelinerjik sistem kardiyovasküler etkileri nedeniyle oldukça önemli olup, dünya çapında yaygın morbidite ve mortalite sebebi olan kardiyovasküler…”
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Dissertation -
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MMP2 Gene-735 C/T and MMP9 gene -1562 C/T Polymorphisms in JAK2V617F Positive Myeloproliferative Disorders
Published in Asian Pacific journal of cancer prevention : APJCP (25-02-2015)Get full text
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Association and Prognostic Significance of the Functional −1562C/T Polymorphism in the Promoter Region of MMP-9 in Turkish Patients with Gastric Cancer
Published in Pathology oncology research (01-09-2015)“…Matrix metalloproteinases (MMPs) are a group of zinc-dependent peptidases that participate in matrix turnover in solid malignancies. The aim of this study was…”
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Spectrum of EGFR gene mutations and ALK rearrangements in lung cancer patients in Turkey
Published in SpringerPlus (19-04-2016)“…The EGFR gene and ALK rearrangements are two genetic drivers of non-small cell lung cancer (NSCLC). The frequency of EGFR mutations and ALK rearrangement…”
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Association of the ACE I/D gene polymorphisms with JAK2V617F-positive polycythemia vera and essential thrombocythemia
Published in Genetic testing and molecular biomarkers (01-06-2015)“…The renin-angiotensin system contributes to cell growth, proliferation, and differentiation in the bone marrow. We investigated the role of the ACE I/D gene…”
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