Search Results - "ŞAHİN, M. FETHİ"

Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors by Eren, Gökçen, Ünlü, Serdar, Nuñez, Maria-Teresa, Labeaga, Luis, Ledo, Francisco, Entrena, Antonio, Banoğlu, Erden, Costantino, Gabriele, Şahin, M. Fethi

“…Three novel series of diaryl heterocyclic derivatives bearing the 2-oxo-5 H-furan, 2-oxo-3 H-1,3-oxazole, and 1 H-pyrazole moieties as the central heterocyclic…”
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Novel and Stereospecific Synthesis of (2S)-3-(2,4,5-Trifluorophenyl)propane-1,2-diol from D-Mannitol by Aktaş, Derya, Fıstıkçı, Meryem, Gündoğdu, Özlem, Seçen, Hasan, Şahin, M. Fethi, Altundaş, Ramazan, Kara, Yunus

“…A stereospecific synthesis of (2S)‐3‐(2,4,5‐trifluorophenyl)propane‐1,2‐diol from D‐mannitol has been developed. The reaction of…”
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Synthesis and antimicrobial activity of new 1,2,4-triazole and 1,3,4-thiadiazole derivatives by Onkol, Tijen, Doğruer, Deniz S, Uzun, Leyla, Adak, Selcen, Ozkan, Semiha, Sahin, M Fethi

“…In this study, new 3-[(1(2H)-phthalazinone-2-yl(methyl/ethyl]-4-aryl-1,2,4-triazole-5-thione and…”
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Investigation of Anti-leishmanial Activity of the Ten Different Hydrazone Derivatives by DİREKEL, Şahin, KARAMAN, Ülkü, TEZCAN, Seda, UTKU, Semra, ASLAN, Gönül, UYSAL, Mehtap, ŞAHİN, M. Fethi, DELİALİOĞLU, Nuran, ÜLGER, Mahmut, EMEKDAŞ, Gürol

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Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors by Dündar, Yasemin, Ünlü, Serdar, Banoğlu, Erden, Entrena, Antonio, Costantino, Gabriele, Nunez, Maria-Teresa, Ledo, Francisco, Şahin, M. Fethi, Noyanalpan, Ningur

“…A series of 3-unsubstituted/substituted-4,5-diphenyl-2-oxo-3 H-1,3-oxazole derivatives were prepared as selective cyclooxygenase-2 (COX-2) inhibitors. Among…”
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Synthesis and biological evaluation of the salicylamide and salicylic acid derivatives as anti-estrogen agents by Dündar, Yasemin, Özatik, Yasemin, Özatik, Orhan, Ergin, Volkan, Önkol, Tijen, Menevşe, Adnan, Erol, Kevser, Sahin, M Fethi

“…Alkylphenols have xenoestrogenic activity, which mimic the action of physiological estrogens and these mimicking activities are mainly mediated by nongenomic…”
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Synthesis and in vitro Biological Activity of New 4,6-Disubstituted 3(2H)-Pyridazinone-acetohydrazide Derivatives by Sukuroglu, Murat, Onkol, Tijen, Onurdağ, Fatma Kaynak, Akalın, Gulsen, Şahin, M. Fethi

“…New 3(2H)-pyridazinone derivatives containing a N’-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized…”
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Synthesis and Crystal Structure of 3-Amino-1-(5-Chloro-2-Hydroxyphenyl)Imidazolidine-2,4-Dione by Aydin, Abdullah, Önkol, Tijen, Akkurt, Mehmet, Büyükgüngör, Orhan, Şahin, M. Fethi

“…The present study describes the synthesis, spectral data, and single crystal X-ray structural analysis of…”
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Synthesis of New 2-[1(2H)-Phthalazinon-2-yl]acetamide and 3-[1(2H)-Phthalazinon-2-yl]propanamide Derivatives as Antinociceptive and Anti-inflammatory Agents by Dogruer, Deniz S., Kupeli, Esra, Yesilada, Erdem, Sahin, M. Fethi

“…As a consequence of our ongoing studies on heterocyclic compounds for new antinociceptive and anti‐inflammatory agents bearing lactam functional group, new…”
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Amide Derivatives of [6-(5-Methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic Acids as Potential Analgesic and Anti-Inflammatory Compounds by Banoglu, Erden, Akoğlu, Çağla, Ünlü, Serdar, Küpeli, Esra, Yeşilada, Erdem, Şahin, M. Fethi

“…In this study, amide derivatives of [6‐(5‐methyl‐3‐phenyl‐pyrazole‐1‐yl)‐3(2H)‐pyridazinone‐2‐yl]acetic acid were synthesized and tested for their in vivo…”
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Novel and enantioselective syntheses of (R)- and (S)-3-hydroxy-4-(2,4,5-trifluorophenyl)butanoic acid: a synthon for sitagliptin and its derivatives by Fistikci, Meryem, Gundogdu, Ozlem, Aktas, Derya, Secen, Hasan, Sahin, M. Fethi, Altundas, Ramazan, Kara, Yunus

“…A new synthetic strategy for (R)- and (S)-3-hydroxy-4-(2,4,5-trifluorophenyl)butanoic acid, a building block in the preparation of sitagliptin and its…”
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Synthesis and Analgesic and Anti-inflammatory Activity of Some New (6-Acyl-2-benzoxazolinone and 6-Acyl-2-benzothiazolinone Derivatives with Acetic Acid and Propanoic Acid Residues by Ünlü, Serdar, Önkol, Tijen, Dündar, Yasemin, Ökçelik, Berna, Küpeli, Esra, Yeşilada, Erdem, Noyanalpan, Ningur, Şahin, M. Fethi

“…In this study for developing potent analgesic and anti‐inflammatory compounds, we synthesized 6‐acyl‐2‐benzoxazolinone and 6‐acyl‐2‐benzothiazolinone…”
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Synthesis and antinociceptive activity of (5-chloro-2(3H)-benzoxazolon-3-yl) propanamide derivatives by Önkol, Tijen, Fethi Sahin, M, Yildirim, Engin, Erol, Kevser, Ito, Shigero

“…In this study, (5-chloro-2(3H)-benzoxazolon-3-yl)propanamide derivatives were synthesized. The chemical structures of the compounds were elucidated by their IR…”
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Investigations of New Pyridazinone Derivatives for the Synthesis of Potent Analgesic and Anti-Inflammatory Compounds with Cyclooxygenase Inhibitory Activity by Ökçelik, Berna, Ünlü, Serdar, Banoglu, Erden, Küpeli, Esra, Yeşilada, Erdem, Şahin, M. Fethi

“…In this study we describe the synthesis of two novel 4‐phenyl‐and 4‐(2‐chlorophenyl)‐6‐(5‐chloro‐2‐oxo‐3H‐benzoxazol‐7‐yl)‐3(2H)‐pyridazinone derivatives…”
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2-(6-Benzoyl-2-oxo-1,3-benzothia-zol-3-yl)acetic acid by Aydın, Abdullah, Akkurt, Mehmet, Onkol, Tijen, Büyükgüngör, Orhan, Sahin, M Fethi

“…In the title compound, C(16)H(11)NO(4)S, the nine-membered fused ring is nearly planar, with maximum deviations from the mean plane of -0.022 (1) Å for the N…”
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Crystal Structure of Methyl-3-(5-chloro-2-oxo-1,3-benzothiazol-3(2H)-yl)-propanoate by AYDlN, Abdullah, ARlCl, Cengiz, AKKURT, Mehmet, AKKOÇ, Yasemin, SAHIN, M. Fethi

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Novel 1,3-diarylpyrazole acrylamides: synthesis, antiplatelet activity screening, and in silico evaluation studies by Baytas, Sultan Nacak, Inceler, Nazan, Ozkan, Yesim, Unlu, Serdar, Fethi Sahin, M.

“…( E )-3-[3-(pyridin-4-yl)-1-phenyl-1 H -pyrazole-4-yl]acryl amides were evaluated for their antiplatelet activities. Compounds 4o and 4r were found as active…”
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Amide Derivatives of [5-Chloro-6-(2-chloro/fluorobenzoyl)-2-benzoxazolinone-3-yl]acetic Acids as Potential Analgesic and Anti-Inflammatory Compounds by Banoglu, Erden, Okçelik, Berna, Kupeli, Esra, Ünlü, Serdar, Yeşilada, Erdem, Amat, Merc?, Caturla, Joan F., Sahin, M. Fethi

“…In this study, we have explored the prevention of gastric side effects such as gastric lesions and bleeding while maintaining the high analgesic and…”
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Synthesis of some pyridazine derivatives carrying urea, thiourea, and sulfonamide moieties and their antimicrobial activity by DOĞRUER, DENİZ S., URLU, ŞÖLEN, ÖNKOL, TİJEN, ÖZÇELİK, BERRİN, ŞAHİN, M. FETHİ

“…Some pyridazine derivatives carrying urea, thiourea, and sulfonamide groups were synthesized and evaluated for their antimicrobial activity against…”
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Synthesis of novel 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/-nonsubstituted benzal)hydrazone derivatives and acetylcholinesterase and butyrylcholinesterase inhibitory activities in vitro by Utku, Semra, Gökçe, Mehtap, Orhan, İlkay, Şahin, M Fethi

“…Abstract In this study thirteen 6-substituted-3(2 H )-pyridazinone-2-acetyl-2-(substituted/-nonsubstituted benzal)hydrazone V derivatives were synthesized as…”
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