Search Results - "Świerzko, Anna S."
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The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System
Published in Frontiers in immunology (21-10-2020)“…Lung diseases are among the leading causes of morbidity and mortality. Complement activation may prevent a variety of respiratory infections, but on the other…”
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2
Collectins and ficolins in neonatal health and disease
Published in Frontiers in immunology (19-12-2023)“…The immune system starts to develop early in embryogenesis. However, at birth it is still immature and associated with high susceptibility to infection…”
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3
Association of Polymorphisms of MASP1/3 , COLEC10 , and COLEC11 Genes with 3MC Syndrome
Published in International journal of molecular sciences (31-07-2020)“…The Malpuech, Michels, Mingarelli, Carnevale (3MC) syndrome is a rare, autosomal recessive genetic- disorder associated with mutations in the , or genes. The…”
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4
The Role of Pulmonary Collectins, Surfactant Protein A (SP-A) and Surfactant Protein D (SP-D) in Cancer
Published in Cancers (10-09-2024)“…Surfactant proteins A and D (SP-A and SP-D) belong to the collectin subfamily of C-type oligomeric lectins. They are pattern-recognition molecules (PRMs), able…”
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Components of the Lectin Pathway of Complement in Solid Tumour Cancers
Published in Cancers (17-03-2022)“…The complement system is an important branch of the humoral innate immune response that can be activated via three distinct pathways (classical, alternative,…”
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Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults
Published in Scientific reports (29-06-2020)“…We investigated clinical associations of ficolins and mannose-binding lectin (MBL) in 157 patients suffering from acute myeloid leukaemia (AML). Concentrations…”
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Components of the Lectin Pathway of Complement in Haematologic Malignancies
Published in Cancers (04-07-2020)“…The complement system is activated cascadically via three distinct major routes: classical pathway (CP), alternative pathway (AP) or lectin pathway (LP). The…”
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Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates
Published in International journal of molecular sciences (05-12-2022)“…Single nucleotide polymorphisms (SNPs) localised to the promoter region of the FCN2 gene are known to influence the concentration of ficolin-2 in human serum…”
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Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates
Published in Frontiers in immunology (11-10-2024)“…Premature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory…”
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10
Insight into the expression of RIG-I-like receptors in human third trimester placentas following ex vivo cytomegalovirus or vesicular stomatitis virus infection
Published in Molecular immunology (01-10-2020)“…•The third trimester placenta expressed all genes encoding RIG-I-like receptors.•The RIG-I and MDA5 expression increased in VSV-infected explants.•The…”
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Association of low ficolin-2 concentration in cord serum with respiratory distress syndrome in preterm newborns
Published in Frontiers in immunology (17-01-2023)“…Ficolin-2 is a serum pattern recognition molecule, involved in complement activation the lectin pathway. This study aimed to investigate the association of…”
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Antibodies Recognizing Yersinia enterocolitica Lipopolysaccharides of Various Chemotypes in Synovial Fluids From Patients With Juvenile Idiopathic Arthritis
Published in Journal of immunology research (2022)“…Yersinia enterocolitica O:3 (YeO3) is considered to be associated with reactive arthritis (ReA), and its lipopolysaccharide (LPS) has been detected in synovial…”
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13
Interactions of ficolin-3 with ovarian cancer cells
Published in Immunobiology (1979) (01-03-2019)“…Ficolin-3 is a pattern-recognition molecule with the ability to activate the lectin pathway of complement. It is found in lung, liver and blood, but its…”
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14
Polymorphisms of the FCN2 Gene 3'UTR Region and Their Clinical Associations in Preterm Newborns
Published in Frontiers in immunology (28-10-2021)“…Ficolin-2 is regarded as an important innate immunity factor endowed with both lectin (carbohydrate recognition) qualities and ability to induce complement…”
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The Role of Yersinia enterocolitica O:3 Lipopolysaccharide in Collagen-Induced Arthritis
Published in Journal of immunology research (12-11-2020)“…Yersinia enterocolitica O:3 is mentioned among the most common arthritogenic pathogens. Bacterial components (including lipopolysaccharide (LPS)) may persist…”
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Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations
Published in Frontiers in immunology (28-01-2020)“…A prospective study of 312 patients [194 with multiple myeloma (MM) and 118 with lymphomas (LYMPH)] receiving high-dose chemotherapy and autologous…”
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Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis
Published in Immunobiology (1979) (01-05-2020)“…•The MBL2 gene A/O and O/O genotypes were more common in TB patients than in controls.•The frequency of C/C genotype (SFTPA2 +26 C > A polymorphism) was lower…”
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Factors involved in initiation and regulation of complement lectin pathway influence postoperative outcome after pediatric cardiac surgery involving cardiopulmonary bypass
Published in Scientific reports (27-02-2019)“…Congenital heart disease (CHD) often requires surgical intervention, and is sometimes associated with life-threatening post-operative complications. We have…”
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Mannose-binding lectin (MBL) in adult patients with inflammatory bowel disease
Published in Immunobiology (1979) (01-01-2020)“…•Median MBL serum levels did not differ between IBD patients and controls.•In MBL2 A/A homozygous CD patients, the median MBL was higher than in controls.•MBL…”
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Mycobacterial antigen 85 complex (Ag85) as a target for ficolins and mannose-binding lectin
Published in International journal of medical microbiology (01-06-2016)“…Abstract The pattern recognition molecules (PRMs) able to activate complement via the lectin pathway are suspected to be involved in the interaction between…”
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