Search Results - "Świderska, Ewa"

Chronic and Transient Hyperglycemia Induces Changes in the Expression Patterns of IL6 and ADIPOQ Genes and Their Associated Epigenetic Modifications in Differentiating Human Visceral Adipocytes by Wróblewski, Adam, Strycharz, Justyna, Świderska, Ewa, Balcerczyk, Aneta, Szemraj, Janusz, Drzewoski, Józef, Śliwińska, Agnieszka

“…Adipokines secreted by hypertrophic visceral adipose tissue (VAT) instigate low-grade inflammation, followed by hyperglycemia (HG)-related metabolic disorders…”
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Molecular Insight into the Interaction between Epigenetics and Leptin in Metabolic Disorders by Wróblewski, Adam, Strycharz, Justyna, Świderska, Ewa, Drewniak, Karolina, Drzewoski, Józef, Szemraj, Janusz, Kasznicki, Jacek, Śliwińska, Agnieszka

“…Nowadays, it is well-known that the deregulation of epigenetic machinery is a common biological event leading to the development and progression of metabolic…”
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Chronic and Intermittent Hyperglycemia Modulates Expression of Key Molecules of PI3K/AKT Pathway in Differentiating Human Visceral Adipocytes by Świderska, Ewa, Strycharz, Justyna, Wróblewski, Adam, Czarny, Piotr, Szemraj, Janusz, Drzewoski, Józef, Śliwińska, Agnieszka

“…Background: Due to its prominence in the regulation of metabolism and inflammation, adipose tissue is a major target to investigate alterations in insulin…”
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Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels) by Szymczak-Pajor, Izabela, Drzewoski, Józef, Świderska, Ewa, Strycharz, Justyna, Gabryanczyk, Anna, Kasznicki, Jacek, Bogdańska, Marta, Śliwińska, Agnieszka

“…Accumulating evidence (mainly from experimental research) suggests that metformin possesses anticancer properties through the induction of apoptosis and…”
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Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus by Wróblewski, Adam, Strycharz, Justyna, Oszajca, Katarzyna, Czarny, Piotr, Świderska, Ewa, Matyjas, Tomasz, Zieleniak, Andrzej, Rucińska, Monika, Pomorski, Lech, Drzewoski, Józef, Śliwińska, Agnieszka, Szemraj, Janusz

“…BACKGROUND Human visceral adipose tissue (VAT), now identified as an endocrine organ, plays a significant role in impaired fasting glucose and diabetes through…”
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Autophagy Inhibition with Chloroquine Increased Pro-Apoptotic Potential of New Aziridine-Hydrazide Hydrazone Derivatives against Glioblastoma Cells by Witusik-Perkowska, Monika, Głowacka, Pola, Pieczonka, Adam M, Świderska, Ewa, Pudlarz, Agnieszka, Rachwalski, Michał, Szymańska, Julia, Zakrzewska, Magdalena, Jaskólski, Dariusz J, Szemraj, Janusz

“…Tumor therapy escape due to undesired side effects induced by treatment, such as prosurvival autophagy or cellular senescence, is one of the key mechanisms of…”
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Visceral Adipose Tissue of Prediabetic and Diabetic Females Shares a Set of Similarly Upregulated microRNAs Functionally Annotated to Inflammation, Oxidative Stress and Insulin Signaling by Strycharz, Justyna, Wróblewski, Adam, Zieleniak, Andrzej, Świderska, Ewa, Matyjas, Tomasz, Rucińska, Monika, Pomorski, Lech, Czarny, Piotr, Szemraj, Janusz, Drzewoski, Józef, Śliwińska, Agnieszka

“…Hypertrophic and hypoxic visceral adipose tissue (VAT) secretes proinflammatory cytokines promoting insulin resistance (IR), prediabetes and type 2 diabetes…”
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Hyperglycemia Changes Expression of Key Adipogenesis Markers (C/EBPα and PPARᵞ) and Morphology of Differentiating Human Visceral Adipocytes by Świderska, Ewa, Podolska, Marta, Strycharz, Justyna, Szwed, Marzena, Abramczyk, Halina, Brożek-Płuska, Beata, Wróblewski, Adam, Szemraj, Janusz, Majsterek, Ireneusz, Drzewoski, Józef, Śliwińska, Agnieszka

“…Disturbances in adipose tissue significantly contribute to the development of metabolic disorders, which are connected with hyperglycemia (HG) and underlain by…”
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Hyperglycemia Affects miRNAs Expression Pattern during Adipogenesis of Human Visceral Adipocytes-Is Memorization Involved? by Strycharz, Justyna, Świderska, Ewa, Wróblewski, Adam, Podolska, Marta, Czarny, Piotr, Szemraj, Janusz, Balcerczyk, Aneta, Drzewoski, Józef, Kasznicki, Jacek, Śliwińska, Agnieszka

“…microRNAs are increasingly analyzed in adipogenesis, whose deregulation, especially visceral, contributes to the development of diabetes. Hyperglycemia is…”
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Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial Cells by Wojtala, Martyna, Dąbek, Arkadiusz, Rybaczek, Dorota, Śliwińska, Agnieszka, Świderska, Ewa, Słapek, Katarzyna, El-Osta, Assam, Balcerczyk, Aneta

“…The methylation of histone lysine residues modifies chromatin conformation and regulates the expression of genes implicated in cell metabolism. Lysine-specific…”
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SIRT1 as a Therapeutic Target in Diabetic Complications by Strycharz, Justyna, Rygielska, Zaneta, Swiderska, Ewa, Drzewoski, Jozef, Szemraj, Janusz, Szmigiero, Leszek, Sliwinska, Agnieszka

“…Sirtuin1 is an epigenetic enzyme involved in histone and nonhistone protein deacetylation. It acts primarily as a metabolic sensor, which responses to changing…”
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Errate: Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus by Wróblewski, Adam, Strycharz, Justyna, Oszajca, Katarzyna, Czarny, Piotr, Świderska, Ewa, Matyjas, Tomasz, Zieleniak, Andrzej, Rucińska, Monika, Pomorski, Lech, Drzewoski, Józef, Śliwińska, Agnieszka, Szemraj, Janusz

“…The authors informed the journal that errors occurred in their manuscript, and were not noticed by the authors during the proofreading. Corrections: 1. Figure…”
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Single-nucleotide polymorphisms of uracil-processing genes affect the occurrence and the onset of recurrent depressive disorder by Czarny, Piotr, Wigner, Paulina, Strycharz, Justyna, Watala, Cezary, Swiderska, Ewa, Synowiec, Ewelina, Galecki, Piotr, Talarowska, Monika, Szemraj, Janusz, Su, Kuan-Pin, Sliwinski, Tomasz

“…Depressive disorders (DD) are known to be associated with increased DNA damage, the impairment of DNA damage repair, and the presence of single-nucleotide…”
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Expression of NFKB1, TIGAR, and a Set of miRNAs Is Upregulated in Visceral Adipose Tissue of Women with T2DM but Not with IFG by Wróblewski, Adam, Strycharz, Justyna, Oszajca, Katarzyna, Czarny, Piotr, Świderska, Ewa, Matyjas, Tomasz, Zieleniak, Andrzej, Rucińska, Monika, Pomorski, Lech, Drzewoski, Józef, Śliwińska, Agnieszka, Szemraj, Janusz

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Mitochondrial DNA copy number, damage, repair and degradation in depressive disorder by Czarny, Piotr, Wigner, Paulina, Strycharz, Justyna, Swiderska, Ewa, Synowiec, Ewelina, Szatkowska, Magdalena, Sliwinska, Agnieszka, Talarowska, Monika, Szemraj, Janusz, Su, Kuan-Pin, Maes, Michael, Sliwinski, Tomasz, Galecki, Piotr

“…Objectives: We aimed to explore mitochondrial DNA (mtDNA) copy number, damage, repair and degradation in peripheral blood mononuclear cells (PBMCs) of patients…”
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