Search Results - "Ļauberte, Lāsma"
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Drastic increase in nitric oxide content in rat brain under halothane anesthesia revealed by EPR method
Published in Biochemical pharmacology (15-12-1999)“…A drastic increase in nitric oxide (NO) content was revealed by the EPR method in rat brain cortex and cerebellum under halothane anesthesia. The NO scavenger…”
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Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures
Published in Neurobiology of disease (01-03-2021)“…There is a growing body of evidence demonstrating the significant involvement of the sigma-1 chaperone protein in the modulation of seizures. Several sigma-1…”
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Reduced GFAP Expression in Bergmann Glial Cells in the Cerebellum of Sigma-1 Receptor Knockout Mice Determines the Neurobehavioral Outcomes after Traumatic Brain Injury
Published in International journal of molecular sciences (27-10-2021)“…Neuroprotective effects of Sigma-1 receptor (S1R) ligands have been observed in multiple animal models of neurodegenerative diseases. Traumatic brain injury…”
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The activity of selective sigma-1 receptor ligands in seizure models in vivo
Published in Behavioural brain research (15-06-2017)“…Sigma-1 receptor (Sig1R) is a ligand-regulated protein which, since its discovery, has been widely studied as a novel target to treat neurological disorders,…”
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Correction of glycaemia and GLUT1 level by mildronate in rat streptozotocin diabetes mellitus model
Published in Cell biochemistry and function (01-01-2011)“…Anti‐ischaemic drug mildronate suppresses fatty acid metabolism and increases glucose utilization in myocardium. It was proposed that it could produce a…”
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Influence of metformin on GLUT1 gene and protein expression in rat streptozotocin diabetes mellitus model
Published in Archives of physiology and biochemistry (01-07-2010)“…Context: Metformin improves hyperglycaemia via mechanisms which include activation of AMP-activated protein kinase (AMPK). Recent findings indicate that some…”
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Effects of γ‐Butyrobetaine and Mildronate on Nitric Oxide Production in Lipopolysaccharide‐Treated Rats
Published in Basic & clinical pharmacology & toxicology (01-01-2004)“…: Production of nitric oxide was measured in lipopolysaccharide‐treated rats (10 mg/kg, 4 hr) using the electron paramagnetic resonance method. As compared to…”
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Identification of an intronic TG repeat polymorphism in the human proteasome core particle PROS-27K gene
Published in DNA sequence (2002)“…A TG dinucleotide repeat was identified in intron 6 of the human proteasome core particle PROS-27K (IOTA, PSMA6) gene. We present data on the length…”
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