Search Results - "İSKENDER, İlker"

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion by Iskender, Ilker, Cypel, Marcelo, Martinu, Tereza, Chen, Manyin, Sakamoto, Jin, Kim, Hyunhee, Yu, Keke, Lin, Huiqing, Guan, Zehong, Hashimoto, Kohei, Waddell, Thomas K, Liu, Mingyao, Keshavjee, Shaf

“…BACKGROUNDIschemia-reperfusion injury related to lung transplantation is a major contributor to early postoperative morbidity and mortality. We hypothesized…”
Get full text

Cytokine filtration modulates pulmonary metabolism and edema formation during ex vivo lung perfusion by Iskender, Ilker, MD, MSc, Cosgun, Tugba, MD, Arni, Stephan, PhD, Trinkwitz, Michael, Fehlings, Stefan, Yamada, Yoshito, MD, PhD, Cesarovic, Nikola, PhD, Yu, Keke, MD, Frauenfelder, Thomas, MD, Jungraithmayr, Wolfgang, MD, PhD, Weder, Walter, MD, Inci, Ilhan, MD

“…Background Ex vivo lung perfusion (EVLP) improved the process of donor-lung management. Cytokine accumulation during EVLP has been shown to correlate with a…”
Get full text

Human α1 -antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model by Iskender, Ilker, MD, MSc, Sakamoto, Jin, MD, Nakajima, Daisuke, MD, Lin, Huiqing, MD, Chen, Manyin, MD, Kim, Hyunhee, MSc, PhD, Guan, Zehong, MSc, Del Sorbo, Lorenzo, MD, Hwang, David, MD, PhD, Waddell, Thomas K., MD, PhD, Cypel, Marcelo, MD, MSc, Keshavjee, Shaf, MD, MSc, Liu, Mingyao, MD, MSc

“…Background The translation of novel drugs in lung transplantation is challenged by different physiologic conditions between small animals and humans…”
Get full text

Extension of donor lung preservation with hypothermic storage after normothermic ex vivo lung perfusion by Hsin, Michael Kuan Yew, MD, Iskender, Ilker, MD, Nakajima, Daisuke, MD, Chen, Manyin, MD, Kim, Hyunhee, MSc, dos Santos, Pedro Reck, MD, Sakamoto, Jin, MD, Lee, Jingu, MD, Hashimoto, Kohei, MD, Harmantas, Constantine, BSc, Hwang, David, MD, Waddell, Tom, MD, PhD, Liu, Mingyao, MD, MSc, Keshavjee, Shaf, MD, Cypel, Marcelo, MD

“…Background Ex vivo lung perfusion (EVLP) allows normothermic evaluation and treatment of donor lungs not currently acceptable for transplant and improves organ…”
Get full text

Importance of Left Atrial Pressure During Ex Vivo Lung Perfusion by Linacre, Virginia, Cypel, Marcelo, Machuca, Tiago, Nakajima, Daisuke, Hashimoto, Kohei, Zamel, Ricardo, Chen, Manyin, Iskender, Ilker, dos Santos, Pedro, Waddell, Thomas K, Liu, Mingyao, Keshavjee, Shaf

“…Background Ex vivo lung perfusion (EVLP) allows for the evaluation and treatment of donor lungs before transplant. Different EVLP strategies have been…”
Get full text

Annexin V homodimer protects against ischemia reperfusion–induced acute lung injury in lung transplantation by Hashimoto, Kohei, MD, Kim, Hyunhee, MSc, Oishi, Hisashi, MD, PhD, Chen, Manyin, MD, Iskender, Ilker, MD, Sakamoto, Jin, MD, Ohsumi, Akihiro, MD, Guan, Zehong, MSc, Hwang, David, MD, PhD, Waddell, Thomas K., MD, PhD, Cypel, Marcelo, MD, MSc, Liu, Mingyao, MD, MSc, Keshavjee, Shaf, MD, MSc

“…Abstract Objective We hypothesized that administration of a homodimer of recombinant annexin V, diannexin, could shield phosphatidylserine on the endothelium,…”
Get full text

Technical Advances Targeting Multiday Preservation of Isolated Ex Vivo Lung Perfusion by Iskender, Ilker

“…Indications for ex vivo lung perfusion (EVLP) have evolved from assessment of questionable donor lungs to treatment of some pathologies and the logistics. Yet…”
Get full text

Modified in vivo lung perfusion allows for prolonged perfusion without acute lung injury by dos Santos, Pedro Reck, MD, Iskender, Ilker, MD, Machuca, Tiago, MD, Hwang, David, MD, dePerrot, Marc, MSc, MD, Liu, Mingyao, MD, Keshavjee, Shaf, MSc, MD, Waddell, Thomas K., MSc, MD, PhD, Cypel, Marcelo, MSc, MD

“…Objectives In vivo lung perfusion (IVLP) is an emergent strategy to treat lung metastases because it allows localized delivery of chemotherapy with minimal…”
Get full text

Functional, Metabolic and Morphologic Results of Ex Vivo Donor Lung Perfusion with a Perfluorocarbon-Based Oxygen Carrier Nanoemulsion in a Large Animal Transplantation Model by Inci, Ilhan, Arni, Stephan, Iskender, Ilker, Citak, Necati, Rodriguez, Josep Monné, Weisskopf, Miriam, Opitz, Isabelle, Weder, Walter, Frauenfelder, Thomas, Krafft, Marie Pierre, Spahn, Donat R

“…Ex vivo lung perfusion (EVLP) is a technology that allows the re-evaluation of questionable donor lung before implantation and it has the potential to repair…”
Get full text

The Experimental Use of N-Butyl Cyanoacrylate Tissue Adhesive in Pulmonary Wedge Resections by Kosar, Altug, MD, Kapicibasi, H. Oguz, MD, Alpay, A. Levent, MD, Misirlioglu, Aysun K., MD, Sonmez, Hakan, MD, Iskender, Ilker, MD, Demirhan, Recep, MD

“…Background In this experimental study, the effectiveness of N-butyl cyanoacrylate tissue adhesive on preventing air leakage after pulmonary wedge resection was…”
Get full text

Perfusate adsorption during ex vivo lung perfusion improves early post-transplant lung function by Iskender, Ilker, Arni, Stephan, Maeyashiki, Tatsuo, Citak, Necati, Sauer, Mareike, Rodriguez, Josep Monné, Frauenfelder, Thomas, Opitz, Isabelle, Weder, Walter, Inci, Ilhan

“…Improvement in ex vivo lung perfusion protocols could increase the number of donors available for transplantation and protect the lungs from primary graft…”
Get full text

Mediasten kaynaklı dev lipom by SÖNMEZ, Hakan, KIR, Altan, ATASALİHİ, Ali, İSKENDER, İlker, KAPICIBAŞI, Hasan Oğuz

“…Elli iki yaşında erkek hasta mediastinal yağlı dokudan kaynaklanan sol hemitoraksı dolduran düzgün kenarlı kapsüllü sol akciğerde atelektaziye neden olan 3.9…”
Get full text

Previous lung volume reduction surgery does not negatively affect survival after lung transplantation by Inci, Ilhan, Iskender, Ilker, Ehrsam, Jonas, Caviezel, Claudio, Hillinger, Sven, Opitz, Isabelle, Schneiter, Didier, Weder, Walter

“…Abstract OBJECTIVES Lung volume reduction surgery (LVRS) and lung transplantation (LTx) are the treatments of choice in selected patients with end-stage…”
Get full text

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation by Mordant, Pierre, Nakajima, Daisuke, Kalaf, Ricardo, Iskender, Ilker, Maahs, Lucas, Behrens, Paula, Coutinho, Rafael, Iyer, Rohin K., Davies, John E., Cypel, Marcelo, Liu, Mingyao, Waddell, Thomas K., Keshavjee, Shaf

“…Ex vivo lung perfusion (EVLP) presents a unique therapeutic opportunity to administer mesenchymal stromal cells (MSCs) to lung grafts before transplantation…”
Get full text

Lung lavage and surfactant replacement during ex vivo lung perfusion for treatment of gastric acid aspiration-induced donor lung injury by Nakajima, Daisuke, Liu, Mingyao, Ohsumi, Akihiro, Kalaf, Ricardo, Iskender, Ilker, Hsin, Michael, Kanou, Takashi, Chen, Manyin, Baer, Brandon, Coutinho, Rafael, Maahs, Lucas, Behrens, Paula, Azad, Sassan, Martinu, Tereza, Waddell, Thomas K, Lewis, James F, Post, Martin, Veldhuizen, Ruud A.W, Cypel, Marcelo, Keshavjee, Shaf

“…Background Ex vivo lung perfusion (EVLP) provides opportunities to treat injured donor lungs before transplantation. We investigated whether lung lavage, to…”
Get full text

Ex vivo treatment with inhaled N-acetylcysteine in porcine lung transplantation by Yamada, Yoshito, Iskender, Ilker, Arni, Stephan, Hillinger, Sven, Cosgun, Tugba, Yu, Keke, Jungraithmayr, Wolfgang, Cesarovic, Nikola, Weder, Walter, Inci, Ilhan

“…We have shown the beneficial effects of N-acetylcysteine (NAC) on posttransplant lung function, when both donor and recipient were pretreated intravenously…”
Get full text

Ex vivo administration of trimetazidine improves post-transplant lung function in pig model by Cosgun, Tugba, Iskender, Ilker, Yamada, Yoshito, Arni, Stephan, Lipiski, Miriam, van Tilburg, Koen, Weder, Walter, Inci, Ilhan

“…Abstract OBJECTIVES: Ex vivo lung perfusion (EVLP) is not only used to assess marginal donor lungs but is also used as a platform to deliver therapeutic agents…”
Get full text

Lung transplantation in patients with a history of anatomical native lung resection by Iskender, Ilker, Pecoraro, Ylenia, Moreno Casado, Paula, Kubisa, Bartosz, Schiavon, Marco, Faccioli, Eleonora, Ehrsam, Jonas, Damarco, Francesco, Nosotti, Mario, Inci, Ilhan, Venuta, Federico, Van Raemdonck, Dirk, Ceulemans, Laurens J

“…OBJECTIVESHistory of anatomical lung resection complicates lung transplantation (LTx). Our aim was to identify indications, intraoperative approach and outcome…”
Get full text

Rare indications for a lung transplant. A European Society of Thoracic Surgeons survey by Nosotti, Mario, D'Ovidio, Frank, Leiva-Juarez, Miguel, Keshavjee, Shaf, Rackauskas, Mindaugas, Van Raemdonck, Dirk, Ceulemans, Laurens J, Krueger, Thorsten, Koutsokera, Angela, Schiavon, Marco, Rea, Federico, Iskender, Ilker, Moreno, Paula, Alvarez, Antonio, Luzzi, Luca, Paladini, Piero, Rosso, Lorenzo, Bertani, Alessandro, Venuta, Federico, Pecoraro, Ylenia, Al-Kattan, Khaled, Kubisa, Bartosz, Inci, Ilhan

“…The European Society of Thoracic Surgeons Lung Transplantation Working Group promoted a survey to evaluate overall survival in a large cohort of patients…”
Get full text

F-081PREVIOUS LUNG VOLUME REDUCTION SURGERY DOES NOT NEGATIVELY AFFECT SURVIVAL AFTER LUNG TRANSPLANTATION by Inci, I., Iskender, Ilker, Ehrsam, J., Caviezel, C., Hillinger, S., Opitz, I., Schneiter, D., Weder, W.

Get full text