Search Results - "Ėksperimentalʹnaâ i kliničeskaâ farmacologiâ"

Role of functional state of neuronal mitochondria of cerebral cortex in mechanisms of nootropic activity of neuroprotectors in rats with alloxan hyperglycemia by Zhiliuk, V I, Mamchur, V I, Pavlov, S V

“…The influence of citicoline, phenylpiracetam, pentoxifylline and N-phenylacetyl-L-prolylglycine on cognitive processes and functional state of mitochondria in…”
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AntI-inflammatory, antipyretic and antimicrobial activity of flavonoid-containing extract of Gratiola officinalis L by Polukonova, N V, Navolokin, N A, Raĭkova, S V, Masliakova, G N, Bucharskaia, A B, Durnova, N A, Shub, G M

“…The extract of Gratiola officinalis L. has been obtained by an original method ensuring the maximum yield of flavonoids. The extract simultaneously exhibits…”
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COMPARATIVE STUDY OF THE HEART FUNCTIONAL RESERVE UNDER STRESS-INDUCED BLOCKADE OF NO-ERGIC SYSTEM AND GABA-A RECEPTORS IN RATS. by Perfilova, V N, Sadikova, N V, Prokof'ev, I I, Inozemtsev, O V, Tyurenkov, I N

“…Cardiac contractility in rats was decreased after 24-h immobilization-painful stressing, as indicated by lower growth rate of myocardium contraction and…”
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Experimental study of the basic pharmacokinetic characteristics of dipeptide carnosine and its efficiency of penetration into brain tissues by Sariev, A K, Abaimov, D A, Tankevich, M V, Pantyukhova, E Yu, Prokhorov, D I, Fedorova, T N, Lopachev, A V, Stvolinskii, S L, Konovalova, E V, Seifulla, R D

“…We have used an original chromatography/mass spectrometry technique to study the pharmacokinetics of dipeptide carnosine in C57 Black/6 mice after…”
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ESTIMATING THE EFFECTIVENESS OF HYPOLIPIDEMIC THERAPY WITH ROSUVASTATIN IN PATIENTS WITH CORONARY HEART DISEASE DEPENDING ON THE GENOTYPE OF LIPOPROTEIN LIPASE by Zvyagina, M V, Mal, G S, Bushueva, O Yu, Alymenko, M A, Bykanova, M A, Letova, I M, Gribovskaya, I A, Churnosov, M I, Solodilova, M A, Polonikov, A V

“…Taking into account the genetic heterogeneity of hyperlipidemias, polymorphic genes involved in the regulation of lipid metabolism may explain differences in…”
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MORPHOLOGICAL CHANGES IN RAT MYOCARDIUM EXPOSED TO HEMIC HYPOXIA AND TREATED WITH CYTOFLAVIN. by Zadnipryanyi, I V, Tret'yakova, O S, Sataeva, T P

“…This study was aimed at determining the influence of cytoflavin on the morphological features of contractile cardiomyocytes in female rats after gestation and…”
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STUDYING GASTRIC ULCERATION EFFECT OF A NEW DRUG INTENDED FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES OF KIDNEYS AND URINARY TRACT. by Murashko, T O, Smirnov, I V, Ivanov, A A, Postnikov, P S, Nemtsev, A O, Bondarev, A A, Udut, V V, Prisukhin, A N, Kornaukhov, A N, Sergeev, T S

“…Gastric ulceration properties (gastrointestinal toxicity) of the sodium salt of 4-(0-β-D-glucopyranosyloxy) benzoic acid, a new nonsteroidal anti-inflammatory…”
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MECHANISMS OF AFOBAZOLE INFLUENCE ON THE NO PRODUCING ENDOTHELIUM FUNCTION AND INDICATORS OF OXIDATIVE STRESS IN RATS WITH EXPERIMENTAL DIABETES MELLITUS. by Dzugkoev, S G, Dzugkoeva, F S, Mozhaeva, I V, Margieva, O I, Karchaidze, N M

“…Data on the mechanisms of afobazole effect on the NO-producing function of endothelium under conditions of oxidative stress in rats with experimental diabetes…”
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CHRONOBIOLOGICAL ACTIVITY OF AQUEOUS EXTRACTS OF THE ABOVE-GROUND PART OF AGRIMONIA PILOSA L. IN RATS. by Zamoshchina, T A, Krasnov, E A, Otmakhov, V I, Petrova, E V, Reshetov, Ya E, Prosekina, E Yu, Tomova, T A, Kuskova, I S

“…It is established that lithium is accumulated in the above-ground part of agrimony (Agrimoniapilosa L.), the aqueous extract of which exhibits lithium-specific…”
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ANTIAGGREGANT ACTIVITY OF A NEW TRICYCLIC BENZIMIDAZOLE DERIVATIVE. by Kucheryavenko, A F, Anisimova, V A, Gaidukova, K A, Divaeva, L N, Kuz'menko, T A, Morkovnik, A S, Sirotenko, V S, Spasov, A A

“…The antiaggregant activity of a new benzimidazole derivative - 2,3,4,5-tetrahydro[1,3]diazepino[1,2-α]benzimidazole (DAB-15) has been investigated in vitro in…”
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CLASSIFICATION AND PRINCIPLES OF ACTION OF ANTIARRHYTHMIC AGENTS. by Popova, E P, Fisenko, V P

“…Data on the pathophysiological mechanisms of arrhythmias and the elecrophysiological mechanisms of antiarrhythmic drug action are reviewed. Development of the…”
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INFLUENCE OF NATURAL COMPOUNDS WITH POLYPHENOL STRUCTURE ON THE VASODILATION FUNCTION OF CEREBROVASCULAR ENDOTHELIUM IN RATS UNDER FOCAL ISCHEMIA CONDITIONS. by Voronkov, A V, D'yakova, I N, Pozdnyakov, D I

“…It was studied the effect of two natural compounds with polyphenol structure, green tea polyphenols (Sigma-Aldrich) and catechol hydrate (Sigma-Aldrich) in a…”
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INFLUENCE OF MEDICINAL PLANT EXTRACTS ON THE FUNCTIONS AND ANTIOXIDANT PROTECTION OF ERYTHROCYTES IN RATS WITH EXPERIMENTAL DIABETES MELLITUS by Vengerovskii, A I, Yakimova, T V, Nasanova, O N

“…Experiments on rats with diabetes mellitus model induced by streptosotocin and high (30%) fat diet showed that the daily treatment with aqueous extracts of…”
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GLUTATHIONE SYSTEM ACTIVITY IN RAT TISSUES UNDER PHENYLETHYL BIGUANIDE ACTION ON THE BACKGROUND OF EXPERIMENTAL BRAIN ISCHEMIA/REPERFUSION DEVELOPMENT by Safonova, O A, Popova, T N, Kryl'skii, D V

“…It was studied the total antioxidant activity, content of primary lipid peroxidation (LPO) products and reduced glutathione, and the activity of glutathione…”
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COMPARISON OF PHARMACOLOGICAL EFFECTS OF HEPTAPEPTIDE SELANK AFTER INTRANASAL AND INTRAPERITONEAL ADMINISTRATION TO BALB/c AND C57BL/6 MICE. by Vasil'eva, E V, Kondrakhin, E A, Salimov, R M, Kovalev, G I

“…Pharmacological effects of intraperitoneal (i.p.) and intranasal (i.n.) administration of heptapeptide selank (300 μg/kg/day for 5 days), known to possess…”
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ASSESSMENT OF SPECIFIC PHARMACOLOGIC ACTIVITY OF UNIFUSOL ON ENDOTHELIUM DYSFUNCTION MODEL INDUCED BY N-NITRO-L-ARGININE METHYL ETHER. by Vasil'evl, A G, Trashkov, A R, Verlov, N A, Kovalenko, A L, Petrov, A Yu, Valeev, V V

“…Specific pharmacologic activity of sodium-L-arginine succinate (unifusol) was studied on endothelium dysfunction model (EDM) in rats. EDM was induced by daily…”
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INCREASING EFFICACY OF PREGRAVIDAR PREPARATION IN MARRIED COUPLES SUFFERING OF INCREASED RISK OF PREGNANCY MISCARRIAGE. by Mal'gina, G B, Belomestnov, S R

“…This study was aimed at revealing clinical and laboratory peculiarities in the health of married couples suffering of pregnancy miscarriage and the possibility…”
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COMPARISON OF CYTOPROTECTIVE EFFECTS OF HEMANTANE AND AMANTADINE UNDER CONDITIONS OF 6-HYDROXYDOPAMINE NEUROTOXIN ACTION ON CULTURED HUMAN NEUROBLASTOMA CELLS by Logvinov, I O, Antipova, T A, Nepoklonov, A V, Valdman, E A

“…Potential neuroprotective activity of the novel antiparkinsonian drug hemantane (hydrochloride N-2-(adamantyl)-hexamethylenimine) in comparison to amantadine…”
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INFLUENCE OF COMBINED PHARMACOLOGICAL AND HYPOXIC PRECONDITIONING ON ANIMAL SURVIVAL AND FUNCTIONAL ACTIVITY OF CNS DURING MODEL CEREBRAL ISCHEMIA. by Levchenkova, O S, Novikov, V E, Kulagin, K N, Ponamareva, N S

“…The combined action of amthizole administration and hypoxia conditions on the survival of rats and the functional state of the central nervous system has been…”
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ANTIPLATELET AND ANTI-ISCHEMIC EFFECTS OF MEMANTINE AND 5-HYDROXYADAMANTAN-2-ONE IN PATIENTS WITH CEREBROVASCULAR PATHOLOGY AND IN EXPERIMENTS by Tanashyan, M M, Shabalina, A A, Gnedovskaya, E V, Gan'shina, T S, Kurza, E V, Maslennikov, D V, Mirzoyan, R S

“…It was investigated the effect of two adamantane derivatives, memantine and 5-hydroxyadamantan-2-one (5-HA), in patients with cerebrovascular disorders. In…”
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