Search Results - "Červenka, Ludĕk"

Endothelin type A receptor blockade increases renoprotection in congestive heart failure combined with chronic kidney disease: Studies in 5/6 nephrectomized rats with aorto-caval fistula by Kala, Petr, Vaňourková, Zdenka, Škaroupková, Petra, Kompanowska-Jezierska, Elżbieta, Sadowski, Janusz, Walkowska, Agnieszka, Veselka, Josef, Táborský, Miloš, Maxová, Hana, Vaněčková, Ivana, Červenka, Luděk

“…Association of congestive heart failure (CHF) and chronic kidney disease (CKD) worsens the patient’s prognosis and results in poor survival rate. The aim of…”
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Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat by Kala, Petr, Bartušková, Hana, Piťha, Jan, Vaňourková, Zdenka, Kikerlová, Soňa, Jíchová, Šárka, Melenovský, Vojtěch, Hošková, Lenka, Veselka, Josef, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Gawrys, Olga, Maxová, Hana, Červenka, Luděk

“…Doxorubicin's (DOX) cardiotoxicity contributes to the development of chemotherapy-induced heart failure (HF) and new treatment strategies are in high demand…”
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Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats by Walkowska, Agnieszka, Červenka, Luděk, Imig, John D, Falck, John R, Sadowski, Janusz, Kompanowska-Jezierska, Elżbieta

“…Cytochrome P450 (CYP-450) metabolites of arachidonic acid: epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) have established role…”
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Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension by Kala, Petr, Gawrys, Olga, Miklovič, Matúš, Vaňourková, Zdenka, Škaroupková, Petra, Jíchová, Šárka, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Walkowska, Agnieszka, Veselka, Josef, Táborský, Miloš, Maxová, Hana, Vaněčková, Ivana, Červenka, Luděk

“…Evaluation of the effect of endothelin type A (ET A ) receptor blockade on the course of volume-overload heart failure in rats with angiotensin II-dependent…”
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Renal sympathetic denervation improves pressure-natriuresis relationship in cardiorenal syndrome: insight from studies with Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula by Honetschlägerová, Zuzana, Husková, Zuzana, Kikerlová, Soňa, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Táborský, Miloš, Vaňourková, Zdenka, Kujal, Petr, Červenka, Luděk

“…The aim was to evaluate the effects of renal denervation (RDN) on autoregulation of renal hemodynamics and the pressure-natriuresis relationship in Ren-2…”
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Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats by Jíchová, Šárka, Gawryś, Olga, Kompanowska-Jezierska, Elżbieta, Sadowski, Janusz, Melenovský, Vojtěch, Hošková, Lenka, Červenka, Luděk, Kala, Petr, Veselka, Josef, Čertíková Chábová, Věra

“…The aim of the present study was to perform kidney messenger ribonucleic acid (mRNA) analysis in normotensive, Hannover Sprague-Dawley (HanSD) rats and…”
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Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats by Baranowska, Iwona, Gawrys, Olga, Walkowska, Agnieszka, Olszynski, Krzysztof H, Červenka, Luděk, Falck, John R, Adebesin, Adeniyi M, Imig, John D, Kompanowska-Jezierska, Elżbieta

“…Numerous studies indicate a significant role for cytochrome P-450-dependent arachidonic acid metabolites in blood pressure regulation, vascular tone, and…”
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Characterization of a new model of chemotherapy-induced heart failure with reduced ejection fraction and nephrotic syndrome in Ren-2 transgenic rats by Gawrys, Olga, Jíchová, Šárka, Miklovič, Matúš, Husková, Zuzana, Kikerlová, Soňa, Sadowski, Janusz, Kollárová, Petra, Lenčová-Popelova, Olga, Hošková, Lenka, Imig, John D., Mazurova, Yvona, Kolář, František, Melenovský, Vojtěch, Štěrba, Martin, Červenka, Luděk

“…All anthracyclines, including doxorubicin (DOXO), the most common and still indispensable drug, exhibit cardiotoxicity with inherent risk of irreversible…”
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The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula by Gawrys, Olga, Husková, Zuzana, Škaroupková, Petra, Honetschlägerová, Zuzana, Vaňourková, Zdeňka, Kikerlová, Soňa, Melenovský, Vojtěch, Bačová, Barbara Szeiffová, Sykora, Matúš, Táborský, Miloš, Červenka, Luděk

“…Heart failure (HF) has been declared as global pandemic and current therapies are still ineffective, especially in patients that develop concurrent…”
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Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure by Jarkovská, Dagmar, Miklovič, Matúš, Švíglerová, Jitka, Červenka, Luděk, Škaroupková, Petra, Melenovský, Vojtěch, Štengl, Milan

“…Chronic volume overload induces multiple cardiac remodeling processes that finally result in eccentric cardiac hypertrophy and heart failure. We have…”
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Fenofibrate Attenuates Malignant Hypertension by Suppression of the Renin-Angiotensin System: A Study in Cyp1a1-Ren-2 Transgenic Rats by Jíchová, Šárka, M.Sc, Doleželová, Šárka, M.Sc, Kopkan, Libor, DVM, Ph.D, Kompanowska-Jezierska, Elzbieta, Ph.D, Sadowski, Janusz, M.D., Ph.D, Červenka, Luděk, M.D., Ph.D

“…Abstract Background Malignant hypertension is a life-threatening condition and its pathophysiology is still poorly understood. The present study was designed…”
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Effects of renal sympathetic denervation on the course of congestive heart failure combined with chronic kidney disease: Insight from studies with fawn-hooded hypertensive rats with volume overload induced using aorto-caval fistula by Honetschlagerová, Zuzana, Škaroupková, Petra, Kikerlová, Soňa, Husková, Zuzana, Maxová, Hana, Melenovský, Vojtěch, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Gawrys, Olga, Kujal, Petr, Červenka, Luděk, Čertíková Chábová, Věra

“…Background: The coincidence of congestive heart failure (CHF) and chronic kidney disease (CKD) results in poor survival rate. The aim of the study was to…”
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Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats by Gawrys, Olga, Husková, Zuzana, Baranowska, Iwona, Walkowska, Agnieszka, Sadowski, Janusz, Kikerlová, Soňa, Vaňourková, Zdeňka, Honetschlägerová, Zuzana, Škaroupková, Petra, Červenka, Luděk, Falck, John R., Imig, John D., Kompanowska-Jezierska, Elzbieta

“…OBJECTIVES:The global morbidity and mortality related to hypertension and associated disorders increases continuously and novel therapeutic strategies are…”
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Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension by Červenka, Luděk, Husková, Zuzana, Kopkan, Libor, Kikerlová, Soňa, Sedláková, Lenka, Vaňourková, Zdenka, Alánová, Petra, Kolář, František, Hammock, Bruce D, Hwang, Sung H, Imig, John D, Falck, John R, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Neckář, Jan

“…OBJECTIVE:We examined the effects of treatment with soluble epoxide hydrolase inhibitor (sEHi) and epoxyeicosatrienoic acids (EETs) analogue (EET-A), given…”
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Enhanced Renal Vascular Responsiveness to Angiotensin II and Norepinephrine: A Unique Feature of Female Rats with Congestive Heart Failure by Krátký, Vojtěch, Kikerlová, Soňa, Husková, Zuzana, Sadowski, Janusz, Kolář, František, Červenka, Luděk

“…Abstract Background/Aims: We found recently that the aortocaval fistula (ACF)-induced heart failure (HF) results in higher mortality in female than in male…”
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Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure by Vacková, Šárka, Kikerlová, Soňa, Melenovsky, Vojtěch, Kolář, František, Imig, John D., Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Červenka, Luděk

“…Objective: We evaluated the hypothesis that the development of renal dysfunction and congestive heart failure (CHF) caused by volume overload in rats with…”
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Sex-Linked Differences in Cardiac Atrophy After Mechanical Unloading Induced by Heterotopic Heart Transplantation by Kolesár, D M, Kujal, P, Mrázová, I, Pokorný, M, Škaroupková, P, Sadowski, J, Červenka, L, Netuka, I

“…No information is available about sex-related differences in unloading-induced cardiac atrophy. We aimed to compare the course of unloading-induced cardiac…”
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Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension by Neckář, Jan, Kopkan, Libor, Husková, Zuzana, Kolář, František, Papoušek, František, Kramer, Herbert J, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Malý, Jiří, Netuka, Ivan, Ošťádal, Bohuslav, Červenka, Luděk

“…The present study was undertaken to evaluate the effects of chronic treatment with c-AUCB {cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid}, a…”
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Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats by Honetschlägerová, Zuzana, Hejnová, Lucie, Novotný, Jiří, Marek, Aleš, Červenka, Luděk

“…Detailed mechanism(s) of the beneficial effects of renal denervation (RDN) on the course of heart failure (HF) remain unclear. The study aimed to evaluate…”
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Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula by Honetschlagerová, Zuzana, Gawrys, Olga, Jíchová, Šárka, Škaroupková, Petra, Kikerlová, Soňa, Vaňourková, Zdeňka, Husková, Zuzana, Melenovský, Vojtěch, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kolář, František, Novotný, Jiří, Hejnová, Lucie, Kujal, Petr, Červenka, Luděk

“…Objective: We examined if renal denervation (RDN) attenuates the progression of aortocaval fistula (ACF)-induced heart failure or improves renal hemodynamics…”
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