Search Results - "Čertíková Chábová, Vera"

Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats by Jíchová, Šárka, Gawryś, Olga, Kompanowska-Jezierska, Elżbieta, Sadowski, Janusz, Melenovský, Vojtěch, Hošková, Lenka, Červenka, Luděk, Kala, Petr, Veselka, Josef, Čertíková Chábová, Věra

“…The aim of the present study was to perform kidney messenger ribonucleic acid (mRNA) analysis in normotensive, Hannover Sprague-Dawley (HanSD) rats and…”
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20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats by Sedláková, Lenka, Kikerlová, Soňa, Husková, Zuzana, Červenková, Lenka, Chábová, Věra Čertíková, Zicha, Josef, Falck, John R, Imig, John D, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Krátký, Vojtěch, Červenka, Luděk, Kopkan, Libor

“…We hypothesized that vascular actions of 20-hydroxyeicosatetraenoic acid (20-HETE), the product of cytochrome P450 (CYP450)-dependent ω-hydroxylase, potentiate…”
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Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease by Čertíková Chábová, Věra, Kujal, Petr, Škaroupková, Petra, Varňourková, Zdeňka, Vacková, Šárka, Husková, Zuzana, Kikerlová, Soňa, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Baranowska, Iwona, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Tesař, Vladimír, Červenka, Ludek

“…Background/Aims: We found recently that increasing renal epoxyeicosatrienoic acids (EETs) levels by blocking soluble epoxide hydrolase (sEH), an enzyme…”
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Fenofibrate Attenuates Hypertension in Goldblatt Hypertensive Rats: Role of 20-Hydroxyeicosatetraenoic Acid in the Nonclipped Kidney by Sporková, Alexandra, Ph.D, Čertíková Chábová, Věra, M.D., Ph.D, Doleželová, Šárka, M.Sc, Jíchová, Šárka, M.Sc, Kopkan, Libor, DVM, Ph.D, Vaňourková, Zdenka, Ph.D, Kompanowska-Jezierska, Elzbieta, Ph.D, Sadowski, Janusz, M.D., Ph.D, Maxová, Hana, Červenka, Luděk, M.D., Ph.D

“…Abstract Background There is vast evidence that the renin-angiotensin system is not the sole determinant of blood pressure (BP) elevation in human renovascular…”
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Pivotal role of angiotensin II receptor subtype 1A in the development of two-kidney, one-clip hypertension: study in angiotensin II receptor subtype 1A knockout mice by Červenka, Luděk, Vaněčková, Ivana, Husková, Zuzana, Vaňourková, Zdenka, Erbanová, Michaela, Thumová, Monika, Škaroupková, Petra, Opočenský, Martin, Malý, Jan, Chábová, Věra Čertíková, Tesař, Vladimír, Bürgelová, Marcela, Viklický, Ondřej, Teplan, Vladimír, Želízko, Michal, Kramer, Herbert J, Navar, L Gabriel

“…OBJECTIVEThe present study was performed to examine in two-kidney, one-clip (2K1C) Goldblatt hypertensive micefirst, the relative contribution of angiotensin…”
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Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats by Sedláková, Lenka, Čertíková Chábová, Věra, Doleželová, Šárka, Škaroupková, Petra, Kopkan, Libor, Husková, Zuzana, Červenková, Lenka, Kikerlová, Soňa, Vaněčková, Ivana, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Kujal, Petr, Kramer, Herbert J., Červenka, Luděk

“…Background: Early addition of endothelin (ET) type A (ET A ) receptor blockade to complex renin-angiotensin system (RAS) blockade has previously been shown to…”
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Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats by Walkowska, Agnieszka, Škaroupková, Petra, Husková, Zuzana, Vaňourková, Zdenka, Chábová, Věra Čertíková, Tesař, Vladimír, Kramer, Herbert J, Falck, John R, Imig, John D, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Červenka, Luděk

“…OBJECTIVEThe contribution of epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) as cytochrome P-450 metabolites of arachidonic acid…”
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Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats by Certíková Chábová, Vera, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kujal, Petr, Vernerová, Zdenka, Vanourková, Zdena, Kopkan, Libor, Kramer, Herbert J, Falck, John R, Imig, John D, Hammock, Bruce D, Vanecková, Ivana, Cervenka, Ludek

“…Recent studies have shown that the renal CYP450 (cytochrome P450) metabolites of AA (arachidonic acid), the vasoconstrictor 20-HETE (20-hydroxyeicosatetraenoic…”
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Effects of Combined Endothelin A Receptor and Renin-Angiotensin System Blockade on the Course of End-Organ Damage in 5/6 Nephrectomized Ren-2 Hypertensive Rats by Vaněčková, Ivana, Kujal, Petr, Husková, Zuzana, Vaňourková, Zdeňka, Vernerová, Zdenka, Čertíková Chábová, Věra, Škaroupková, Petra, Kramer, Herbert J., Tesař, Vladimír, Červenka, Luděk

“…Our previous studies in rats with ablation nephrectomy have shown similar cardiorenal protective effects of renin-angiotensin system (RAS)-dependent treatment…”
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Sodium Glucose Cotransporter-2 Inhibitors: Spotlight on Favorable Effects on Clinical Outcomes beyond Diabetes by Čertíková Chábová, Věra, Zakiyanov, Oskar

“…Sodium glucose transporter type 2 (SGLT2) molecules are found in proximal tubules of the kidney, and perhaps in the brain or intestine, but rarely in any other…”
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Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats by Chábová, Věra Čertíková, Kramer, Herbert J, Vaněčková, Ivana, Vernerová, Zdena, Eis, Václav, Tesař, Vladimír, Škaroupková, Petra, Thumová, Monika, Schejbalová, Stanislava, Husková, Zuzana, Vaňourková, Zdenka, Kolský, Alexander, Imig, John D, Červenka, Luděk

“…Abstract The aim of the present study was to evaluate the effects of inhibition of cytochrome P-450 (CYP) activity by 1-aminobenzotriazole (ABT) and by CoCl2 ,…”
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AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension by Vaňourková, Zdenka, Kramer, Herbert J, Husková, Zuzana, Vaněčková, Ivana, Opočenský, Martin, Chábová, Věra Čertíková, Tesař, Vladimír, Škaroupková, Petra, Thumová, Monika, Dohnalová, Michaela, Mullins, John J, Červenka, Luděk

“…OBJECTIVEIn the present study we compared the effects of treatment with the AT1 receptor antagonist candesartan and of ‘triple therapy’ (hydralazine,…”
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Late-onset endothelin receptor blockade in hypertensive heterozygous REN-2 transgenic rats by Vernerová, Zdenka, Kramer, Herbert J, Bäcker, Angela, Červenka, Luděk, Opočenský, Martin, Husková, Zuzana, Vaňourková, Zdeňka, Eis, Václav, Chábová, Věra Čertíková, Tesař, Vladimír, Malý, Jan, Vaněčková, Ivana

“…Abstract Our previous studies in heterozygous Ren-2 transgenic rats (TGR) have shown that early treatment with selective endothelin (ET)A receptor blockade is…”
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Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension by Vaňourková, Zdeňka, Kramer, Herbert J, Erbanová, Michaela, Bäcker, Angela, Červenka, Luděk, Husková, Zuzana, Chábová, Věra Čertíková, Tesař, Vladimír, Dvořák, Pavel, Malý, Jan, Vaněčková, Ivana

“…Abstract We found previously that selective blockade of endothelin ETA receptors is superior to nonselective ETA /ETB in attenuating hypertension and survival…”
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Clinical Features, Outcomes, and Response to Corticosteroid Treatment of Acute Tubulointerstitial Nephritis: A Single-Centre Retrospective Cohort Study in the Czech Republic by Zakiyanov, Oskar, Ḉaḡlar, Yaprak, Ryšavá, Romana, Jančová, Eva, Maixnerová, Dita, Frausová, Doubravka, Indra, Tomáš, Honsová, Eva, Kříha, Vítězslav, Rychlík, Ivan, Tesař, Vladimír, Čertíková Chábová, Věra

“…Abstract Introduction: Acute tubulointerstitial nephritis (ATIN) is a well-recognized cause of acute kidney injury (AKI) due to the tubulointerstitial…”
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Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats by Čertíková Chábová, Věra, Kujal, Petr, Vaňourková, Zdeňka, Škaroupková, Petra, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Tesař, Vladimír, Hammock, Bruce, Imig, John, Maxová, Hana, Červenka, Luděk, Vaněčková, Ivana

“…Introduction: Previous studies in Ren-2 transgenic hypertensive rats (TGR) after 5/6 renal ablation (5/6 NX) have shown that besides pharmacological blockade…”
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Addition of ETA receptor blockade increases renoprotection provided by renin–angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats by Čertíková Chábová, Věra, Vernerová, Zdenka, Kujal, Petr, Husková, Zuzana, Škaroupková, Petra, Tesař, Vladimír, Kramer, Herbert J., Kompanowska-Jezierska, Elzbieta, Walkowska, Agnieszka, Sadowski, Janusz, Červenka, Luděk, Vaněčková, Ivana

“…There is evidence that in addition to hypertension and hyperactivity of the renin–angiotensin system (RAS), enhanced intrarenal activity of endothelin (ET)…”
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Effects of renal sympathetic denervation on the course of congestive heart failure combined with chronic kidney disease: Insight from studies with fawn-hooded hypertensive rats with volume overload induced using aorto-caval fistula by Honetschlagerová, Zuzana, Škaroupková, Petra, Kikerlová, Soňa, Husková, Zuzana, Maxová, Hana, Melenovský, Vojtěch, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Gawrys, Olga, Kujal, Petr, Červenka, Luděk, Čertíková Chábová, Věra

“…Background: The coincidence of congestive heart failure (CHF) and chronic kidney disease (CKD) results in poor survival rate. The aim of the study was to…”
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Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats by Kujal, Petr, Čertíková Chábová, Vera, Škaroupková, Petra, Husková, Zuzana, Vernerová, Zdena, Kramer, Herbert J, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kitada, Kento, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Červenka, Ludek

“…Summary The aim of the present study was to test the hypothesis that increasing kidney tissue concentrations of epoxyeicosatrienoic acids (EETs) by preventing…”
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Late-Onset Endothelin-A Receptor Blockade Reduces Podocyte Injury in Homozygous Ren-2 Rats Despite Severe Hypertension by Opočenský, Martin, Kramer, Herbert J, Bäcker, Angela, Vernerová, Zdenka, Eis, Václav, Červenka, Luděk, Chábová, Věra Čertíková, Tesař, Vladimír, Vaněčková, Ivana

“…We have recently found in male homozygous hypertensive Ren-2 transgenic rats (TGRs) fed a high-salt diet that early onset selective endothelin (ET) A (ETA) or…”
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