Search Results - "Čekan, Pavol"

A SARS-CoV-2 mutant from B.1.258 lineage with ∆H69/∆V70 deletion in the Spike protein circulating in Central Europe in the fall 2020 by Brejová, Broňa, Boršová, Kristína, Hodorová, Viktória, Čabanová, Viktória, Reizigová, Lenka, Paul, Evan D., Čekan, Pavol, Klempa, Boris, Nosek, Jozef, Vinař, Tomáš

“…SARS-CoV-2 mutants carrying the ∆H69/∆V70 deletion in the amino-terminal domain of the Spike protein emerged independently in at least six lineages of the…”
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Software Design to Calculate of Vibration for a More Effective Assessment of the Safety of the Working Environment by Čekan, Pavol, Balog, Karol, Harangozó, Jozef, Rusko, Miroslav

“…A lot of software that is developed simultaneously with the development of new measuring devices are very difficult to control. The results obtained from the…”
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Surveillance of SARS-CoV-2 lineage B.1.1.7 in Slovakia using a novel, multiplexed RT-qPCR assay by Boršová, Kristína, Paul, Evan D., Kováčová, Viera, Radvánszka, Monika, Hajdu, Roman, Čabanová, Viktória, Sláviková, Monika, Ličková, Martina, Lukáčiková, Ľubomíra, Belák, Andrej, Roussier, Lucia, Kostičová, Michaela, Líšková, Anna, Maďarová, Lucia, Štefkovičová, Mária, Reizigová, Lenka, Nováková, Elena, Sabaka, Peter, Koščálová, Alena, Brejová, Broňa, Staroňová, Edita, Mišík, Matej, Vinař, Tomáš, Nosek, Jozef, Čekan, Pavol, Klempa, Boris

“…The emergence of a novel SARS-CoV-2 B.1.1.7 variant sparked global alarm due to increased transmissibility, mortality, and uncertainty about vaccine efficacy,…”
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Identification of Single-Base Mismatches in Duplex DNA by EPR Spectroscopy by Cekan, Pavol, Sigurdsson, Snorri Th

“…The spin-labeled nucleoside T C, containing 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) conjugated to the exocyclic amino group of C, was used to detect…”
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Relative Orientation of Rigid Nitroxides by PELDOR: Beyond Distance Measurements in Nucleic Acids by Schiemann, Olav, Cekan, Pavol, Margraf, Dominik, Prisner, Thomas F, Sigurdsson, Snorri Th

“…Show me your angle: Incorporation of the rigid spin label Ç allows determination of both distance and orientation of two nitroxide spin labels in DNA by PELDOR…”
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Conformation and dynamics of nucleotides in bulges and symmetric internal loops in duplex DNA studied by EPR and fluorescence spectroscopies by Cekan, Pavol, Sigurdsson, Snorri Th

“…► Bulges and loops were studied by both EPR and fluorescence spectroscopies using the probe Ç/Çf. ► One-base bulge was in a temperature-dependent equilibrium…”
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Vivid COVID-19 LAMP is an ultrasensitive, quadruplexed test using LNA-modified primers and a zinc ion and 5-Br-PAPS colorimetric detection system by Szobi, Adrián, Buranovská, Katarína, Vojtaššáková, Nina, Lovíšek, Daniel, Özbaşak, Halil Önder, Szeibeczederová, Sandra, Kapustian, Liudmyla, Hudáčová, Zuzana, Kováčová, Viera, Drobná, Diana, Putaj, Piotr, Bírová, Stanislava, Čirková, Ivana, Čarnecký, Martin, Kilián, Peter, Jurkáček, Peter, Čabanová, Viktória, Boršová, Kristína, Sláviková, Monika, Vaňová, Veronika, Klempa, Boris, Čekan, Pavol, Paul, Evan D.

“…Sensitive and rapid point-of-care assays have been crucial in the global response to SARS-CoV-2. Loop-mediated isothermal amplification (LAMP) has emerged as…”
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Sequential development of several RT‐qPCR tests using LNA nucleotides and dual probe technology to differentiate SARS‐CoV‐2 from influenza A and B by Radvánszka, Monika, Paul, Evan D., Hajdu, Roman, Boršová, Kristína, Kováčová, Viera, Putaj, Piotr, Bírová, Stanislava, Čirková, Ivana, Čarnecký, Martin, Buranovská, Katarína, Szobi, Adrián, Vojtaššáková, Nina, Drobná, Diana, Čabanová, Viktória, Sláviková, Monika, Ličková, Martina, Vaňová, Veronika, Fumačová Havlíková, Sabína, Lukáčiková, Ľubomíra, Kajanová, Ivana, Koči, Juraj, Rusňáková, Diana, Sedláčková, Tatiana, Max, Klaas E. A., Tuschl, Thomas, Szemes, Tomáš, Klempa, Boris, Čekan, Pavol

“…Summary Sensitive and accurate RT‐qPCR tests are the primary diagnostic tools to identify SARS‐CoV‐2‐infected patients. While many SARS‐CoV‐2 RT‐qPCR tests are…”
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Development and validation of mFISHseq: A diagnostic test using multiplexed RNA-FISH–guided laser capture microdissection RNA sequencing by Loeffler, Chiara Maria Lavinia, Paul, Evan David, Huraiová, Barbora, Matyašovská, Natália, Valková, Natália, Gábrišová, Daniela, Gubová, Soňa, Ignačáková, Helena, Ondris, Tomáš, Bendíková, Silvia, Lovíšek, Daniel, Ristová, Michaela, Gala, Michal, Comino-Méndez, Iñaki, Morozov, Pavel, Barrett, J. Carl Carl, Pareja, Fresia, Kather, Jakob Nikolas, Čekan, Pavol

“…3069 Background: Breast cancer (BCa) is a heterogeneous disease requiring precise diagnostic tools to guide effective treatment strategies. Current diagnostic…”
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Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe C by Edwards, Thomas E, Cekan, Pavol, Reginsson, Gunnar W, Shelke, Sandip A, Ferré-D'Amaré, Adrian R, Schiemann, Olav, Sigurdsson, Snorri Th

“…Previously, we developed the deoxycytosine analog Ç (C-spin) as a bi-functional spectroscopic probe for the study of nucleic acid structure and dynamics using…”
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Conformational Equilibria of Bulged Sites in Duplex DNA Studied by EPR Spectroscopy by Smith, Alyssa L, Cekan, Pavol, Brewood, Greg P, Okonogi, Tamara M, Alemayehu, Saba, Hustedt, Eric J, Benight, Albert S, Sigurdsson, Snorri Th, Robinson, Bruce H

“…Conformational flexibility in nucleic acids provides a basis for complex structures, binding, and signaling. One-base bulges directly neighboring single-base…”
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Identification of RNA-protein interaction networks using PAR-CLIP by Ascano, Manuel, Hafner, Markus, Cekan, Pavol, Gerstberger, Stefanie, Tuschl, Thomas

“…All mRNA molecules are subject to some degree of post‐transcriptional gene regulation (PTGR) involving sequence‐dependent modulation of splicing, cleavage and…”
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Analytical method to determine the orientation of rigid spin labels in DNA by Marko, Andriy, Margraf, Dominik, Cekan, Pavol, Sigurdsson, Snorri Th, Schiemann, Olav, Prisner, Thomas F

“…We demonstrate the ability of pulsed electron double resonance (PELDOR) experiments to determine the orientation of spin labels in biological macromolecules…”
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Single base interrogation by a fluorescent nucleotide: each of the four DNA bases identified by fluorescence spectroscopy by Cekan, Pavol, Sigurdsson, Snorri Th

“…Nucleoside C, which contains a rigid nitroxide spin label, is effectively reduced in DNA by sodium sulfide to the corresponding amine, yielding a fluorescent…”
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A non-radioactive, improved PAR-CLIP and small RNA cDNA library preparation protocol by Anastasakis, Dimitrios G, Jacob, Alexis, Konstantinidou, Parthena, Meguro, Kazuyuki, Claypool, Duncan, Cekan, Pavol, Haase, Astrid D, Hafner, Markus

“…Abstract Crosslinking and immunoprecipitation (CLIP) methods are powerful techniques to interrogate direct protein-RNA interactions and dissect…”
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Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer by Birknerova, Natalia, Mancikova, Veronika, Paul, Evan David, Matyasovsky, Jan, Cekan, Pavol, Palicka, Vladimir, Parova, Helena

“…Head and neck cancer (HNC) remains one of the leading causes of mortality worldwide due to tumor diagnosis at a late stage, loco-regional aggression, and…”
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RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence by Cekan, Pavol, Hasegawa, Keisuke, Pan, Yu, Tubman, Emily, Odde, David, Chen, Jin-Qiu, Herrmann, Michelle A, Kumar, Sheetal, Kalab, Petr

“…The coordination of cell cycle progression with the repair of DNA damage supports the genomic integrity of dividing cells. The function of many factors…”
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Conformational Flexibility of DNA by Marko, Andriy, Denysenkov, Vasyl, Margraf, Dominik, Cekan, Pavol, Schiemann, Olav, Sigurdsson, Snorri Th, Prisner, Thomas F

“…Pulsed Electron–Electron Double Resonance (PELDOR) on double-stranded DNA (ds-DNA) was used to investigate the conformational flexibility of helical DNA…”
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Multiplexed miRNA fluorescence in situ hybridization for formalin-fixed paraffin-embedded tissues by Renwick, Neil, Cekan, Pavol, Bognanni, Claudia, Tuschl, Thomas

“…Multiplexed miRNA fluorescence in situ hybridization (miRNA FISH) is an advanced method for visualizing differentially expressed miRNAs, together with other…”
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A Nucleoside That Contains a Rigid Nitroxide Spin Label: A Fluorophore in Disguise by Barhate, Nivrutti, Cekan, Pavol, Massey, Archna P., Sigurdsson, Snorri Th

“…Take a spin: The nucleoside Ç (C‐spin), which contains a rigid nitroxide spin label, allows the structure and dynamics of nucleic acids into which it is…”
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