Search Results - "ÜNAL, Gülin ÖZDAMAR"

Novel splice‑site variants c.393G>A, c.278_2A>G in exon 2 and Q705K variant in exon 3 of NLRP3 gene are associated with bipolar I disorder by Öztürk, Kuyaş, Ünal, Güli̇n

“…NOD-like receptor pyrin domain-containing 3 (NLRP3) has been considered to play a crucial role in triggering the host's immune and inflammatory responses…”
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Maternal prenatal stress and depression‐like behavior associated with hippocampal and cortical neuroinflammation in the offspring: An experimental study by Özdamar Ünal, Gülin, Hekimler Öztürk, Kuyaş, Erkılınç, Gamze, Dönmez, Feyza, Kumbul Doğuç, Duygu, Özmen, Özlem, Sezik, Mekin

“…Prenatal stress can negatively impact neonatal health, growth, and bonding with the mother. However, molecular basis of these modifications is not completely…”
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The Relationship between Internalized Stigma, Perceived Social Support and Self-Efficacy in Bipolar Disorder by ÖZDAMAR ÜNAL, Gülin, ÖNAL, Bektaş, İŞCAN, Gökçe, ATAY, İnci

“…Objectives: Many people with mental illness are subject to social and objective exclusion, discrimination, and stigma. One of the mental illnesses most exposed…”
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The occurrence and consequences of violence against healthcare workers in Turkey: before and during the COVID-19 pandemic by Özdamar Ünal, Gülin, İşcan, Gökçe, Ünal, Onur

“…Before and throughout the COVID-19 pandemic, healthcare workers (HCWs) were victims of workplace violence (WPV). There are no reliable statistics on the…”
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Bipolar 1 bozukluk hastalarında indolamin 2,3 dioksijenaz enzim ekspresyonu ve kinürenin yolağı metabolitlerinin incelenmesi: Investigation of indoleamine 2,3 dioxygenase enzyme expression and kynurenine pathway metabolites in patients with bipolar 1 disorder / Dr. Bektaş Önal ; tez danışmanı, Dr. Öğr. Üyesi Gülin Özdamar Ünal by Önal, Bektaş, Özdamar Ünal, Gülin

“…AMAÇ: Literatürdeki kanıtlar kinürenin yolağının, nöroinflamasyonun ve bunların karşılıklı etkileşimlerinin bipolar bozukluğun etiyopatogenezinde etkili…”
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Kronik öngörülmeyen stres depresyon modelinde hipokampal nöronlarda erken yaşam stresinin, ketamin ve fluoksetin tedavilerinin sırt1, MİRNA-34A, NLRP3 yolağı ve BDNF, NR2 düzeyleri üzerine etkisi: Effects of early life stress, ketamine and fluoxetine treatments on SIRT1, MİRNA34A, NLRP3 Pathway and BDNF, NR2 levels in hippocampal neurons in the chronic unpredictable stress depression model / Dr. Feyza Dönmez ; tez danışmanı, Dr.Öğr.Üyesi Gülin Özdamar Ünal by Dönmez, Feyza, Özdamar Ünal, Gülin

“…Erken yaşam stresi; nöroplastisite, nöroinflamasyon, epigenetik değişiklikler ve glutamaterjik sistem dahil olmak üzere çeşitli mekanizmalarla majör depresyon…”
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The Association of Death Anxiety, Loneliness, and Hopelessness with Clinical Features and Qualityof Life in Palliative Radiotherapy Patients by kaymak, zümrüt arda

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Bipolar I bozukluk hastalarında NLRP3 inflamazom aktivasyonunun değerlendirilmesi: Evaluation of NLRP3 inflammasome activation in bipolar i disorder patients / Dr. Hüseyin Emre İnci ; tez danışmanı, Dr. Öğr. Üyesi Gülin Özdamar Ünal by İnci, Hüseyin Emre, Özdamar Ünal, Gülin

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Ratlarda oluşturulan kronik hafif stres modelinde hipokampal nöronlarda agomelatinin apopitoz, kalsiyum sinyali ve oksidatif stres üzerine etkisi: The effect of agomelatine on apoptosis, calcium signal and oxidative stress in hippocampal neurons in the model of depression in rats / Dr. Gülin Özdamar Ünal ; tez danışmanları, Yrd.Doç.Dr.Arif Demirdaş, Prof.Dr. Mustafa Nazıroğlu by Özdamar Ünal, Gülin, Nazıroğlu, Mustafa, Demirdaş, Arif

“…Yaşam boyu yaygınlığı %9-20 olarak bildirilen major depresif bozukluk depreşme, yineleme ve yüksek süreğenleşme ile seyreden, fiziksel, ruhsal, sosyal ve…”
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Vareniklin Kullanımı Sonrası İleri Yaş Başlangıçlı Mani: Bir Olgu Sunumu by AKPINAR, Abdullah, ÜNAL, Gülin ÖZDAMAR, ATAY, İnci Meltem, GÜNDOĞAR, Duru, ÖZÇANKAYA, Ramazan

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Vareniklin Kullanimi Sonrasi Ileri Yas Baslangiçli Mani: Bir Olgu Sunumu/Late-life Onset Mania After Varenicline Use: A Case Report by Akpinar, Abdullah, Ünal, Gülin Özdamar, Atay, Inci Meltem, Gündogar, Duru, Özçankaya, Ramazan

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Experimental model of unpredictable maternal stress and diabetes risk of offspring: An immunohistochemical study by Ozmen, Ozlem, Topsakal, Senay, Ozdamar Unal, Gulin

“…The effect of stress on the occurrence of diabetes mellitus (DM) is commonly reported in recent studies. Maternal stress may have a negative effect on the…”
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The beneficial effects of vortioxetine on BDNF, CREB, S100B, β amyloid, and glutamate NR2b receptors in chronic unpredictable mild stress model of depression by Ünal, Gülin Özdamar, Erkılınç, Gamze, Öztürk, Kuyaş Hekimler, Doguç, Duygu Kumbul, Özmen, Özlem

“…Background Depression, one of the most significant mental disorders, is still poorly understood in terms of its pathogenetic mechanisms despite its…”
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Dexpanthenol may protect the brain against lipopolysaccharide induced neuroinflammation via anti-oxidant action and regulating CREB/BDNF signaling by Ozdamar Unal, Gülin, Asci, Halil, Erzurumlu, Yalcın, Ilhan, Ilter, Hasseyid, Nursel, Ozmen, Ozlem

“…Neuroinflammation plays an important role in the pathogenesis of many psychiatric and neurodegenerative diseases. Dexpanthenol (Dex) is an alcoholic analogue…”
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Increased NLRP3 inflammasome expression in peripheral blood mononuclear cells of patients with schizophrenia: a case-control study by Ozdamar Unal, Gulin, Hekimler Ozturk, Kuyas, Inci, Huseyin Emre

“…This study aimed to evaluate the gene expression of the P2X purinoceptor 7 (P2X7R)- nod-like receptor pyrin domain-containing protein 3 (NLRP3) signal pathway…”
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LGBTI Healthcare in Medical Education by Elboga, Gulcin, Kocamer Sahin, Sengul, Demir, Bahadır, Ozdamar Unal, Gulin, Alparslan, Beyza, Altıntaş, Ezel, Marangoz, Talip Kerem, Guneyligil Kazaz, Tanyeli, Altindag, Abdurrahman

“…Our aim is to reveal the interaction of cultural and religious influences with professional equipment by determining the level of knowledge, sexual attitudes,…”
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Complementary and alternative medicine use and its association with clinical features and functioning in patients with bipolar I disorder: A cross-sectional study by Ozdamar Unal, Gulin

“…Objective: The use of complementary and alternative medicines (CAM) has increased recently among those with serious mental disorders. However, CAM use and…”
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Agomelatine reduces brain, kidney and liver oxidative stress but increases plasma cytokine production in the rats with chronic mild stress-induced depression by Demirdas, Arif, Nazirolu, Mustafa, Ünal, Gülin Özdamar

“…Agomelatine (AGOM) as an antidepressant acts both as a melatonin-receptor agonist and a selective serotonin-receptor antagonist. As a potent melatonin derived…”
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Hypothalamic NR3C1 DNA methylation in rats exposed to prenatal stress by Öztürk, Kuyaş Hekimler, Ünal, Gülin Özdamar, Doğuç, Duygu Kumbul, Toğay, Vehbi Atahan, Koşar, Pınar Aslan, Sezik, Mekin

“…Background Human and animal studies have indicated that maternal prenatal stress (PS) has molecular and behavioral effects during pregnancy and early life. The…”
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Do patients with major depressive disorder and generalized anxiety disorder experience more somatosensorial amplification, hypochondriasis, and fear of COVID-19? by Ozdamar Unal, Gulin

“…Objective: Mental illnesses are important determinants in response to the pandemic. However, there are only a limited number of studies investigating the…”
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