Search Results - "Øyan, Anne Margrete"

Dual Pro- and Anti-Inflammatory Features of Monocyte-Derived Dendritic Cells by Azeem, Waqas, Bakke, Ragnhild Maukon, Appel, Silke, Øyan, Anne Margrete, Kalland, Karl-Henning

“…The transcription factor β-catenin is able to induce tolerogenic/anti-inflammatory features in different types of dendritic cells (DCs). Monocyte-derived…”
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Novel STAT3 Inhibitors Targeting STAT3 Dimerization by Binding to the STAT3 SH2 Domain by Hua, Yaping, Yuan, Xing, Shen, Yun-heng, Wang, Jinxin, Azeem, Waqas, Yang, Shuo, Gade, Alexandra, Lellahi, Seyed Mohammad, Øyan, Anne Margrete, Ke, Xisong, Zhang, Wei-dong, Kalland, Karl-Henning

“…Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In…”
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An androgen response element driven reporter assay for the detection of androgen receptor activity in prostate cells by Azeem, Waqas, Hellem, Margrete Reime, Olsen, Jan Roger, Hua, Yaping, Marvyin, Kristo, Qu, Yi, Lin, Biaoyang, Ke, Xisong, Øyan, Anne Margrete, Kalland, Karl-Henning

“…The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of…”
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Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells by Ke, Xi-Song, Qu, Yi, Cheng, Yang, Li, Wen-Cheng, Rotter, Varda, Øyan, Anne Margrete, Kalland, Karl-Henning

“…Previously we reported extensive gene expression reprogramming during epithelial to mesenchymal transition (EMT) of primary prostate cells. Here we…”
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Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells by Bruserud, Oystein, Ryningen, Anita, Olsnes, Astrid Marta, Stordrange, Laila, Oyan, Anne Margrete, Kalland, Karl Henning, Gjertsen, Bjorn Tore

“…From the Division for Hematology, Department of Medicine, Haukeland University Hospital and The University of Bergen, Bergen, Norway (OB, AR, AMartO, BTG);…”
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Evaluation of β-Catenin Inhibition of Axitinib and Nitazoxanide in Human Monocyte-Derived Dendritic Cells by Azeem, Waqas, Bakke, Ragnhild Maukon, Gabriel, Benjamin, Appel, Silke, Øyan, Anne Margrete, Kalland, Karl-Henning

“…Modulation of β-catenin signaling has attractive therapeutic potential in cancer immunotherapy. Several studies have found that β-catenin can mediate immune…”
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Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model by Moen, Ingrid, Øyan, Anne Margrete, Kalland, Karl-Henning, Tronstad, Karl Johan, Akslen, Lars Andreas, Chekenya, Martha, Sakariassen, Per Øystein, Reed, Rolf Kåre, Stuhr, Linda Elin Birkhaug

“…Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced…”
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Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation by Ke, Xi-Song, Qu, Yi, Goldfinger, Naomi, Rostad, Kari, Hovland, Randi, Akslen, Lars A, Rotter, Varda, Øyan, Anne Margrete, Kalland, Karl-Henning

“…Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro…”
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Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival by Mauland, Karen Klepsland, Wik, Elisabeth, Hoivik, Erling A, Kusonmano, Kanthida, Halle, Mari Kyllesø, Berg, Anna, Haugland, Hans Kristian, Øyan, Anne Margrete, Kalland, Karl-Henning, Stefansson, Ingunn Marie, Akslen, Lars A, Krakstad, Camilla, Trovik, Jone, Werner, Henrica Maria Johanna, Salvesen, Helga Birgitte

“…Aneuploidy is a widely studied prognostic marker in endometrial cancer (EC), however, not implemented in clinical decision-making. It lacks validation in large…”
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Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer by Qu, Yi, Gharbi, Naouel, Yuan, Xing, Olsen, Jan Roger, Blicher, Pernille, Dalhus, Bjørn, Brokstad, Karl A., Lin, Biaoyang, Øyan, Anne Margrete, Zhang, Weidong, Kalland, Karl-Henning, Ke, Xisong

“…Oncogenic mutations of the Wnt (wingless)/β-catenin pathway are frequently observed in major cancer types. Thus far, however, no therapeutic agent targeting…”
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Increased Expression of SIM2-s Protein Is a Novel Marker of Aggressive Prostate Cancer by Halvorsen, Ole Johan, Rostad, Kari, Øyan, Anne Margrete, Puntervoll, Hanne, Bø, Trond Hellem, Stordrange, Laila, Olsen, Sue, Haukaas, Svein Andreas, Hood, Leroy, Jonassen, Inge, Kalland, Karl-Henning, Akslen, Lars Andreas

“…Purpose: The human SIM2 gene is located within the Down's syndrome critical region of chromosome 21 and encodes transcription factors involved in brain…”
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A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer by Thomsen, Liv Cecilie Vestrheim, Honoré, Alfred, Reisæter, Lars Anders Rokne, Almås, Bjarte, Børretzen, Astrid, Helle, Svein Inge, Førde, Kristina, Kristoffersen, Einar Klæboe, Kaada, Silje Helland, Melve, Guro Kristin, Haslerud, Torjan Magne, Biermann, Martin, Bigalke, Iris, Kvalheim, Gunnar, Azeem, Waqas, Olsen, Jan Roger, Gabriel, Benjamin, Knappskog, Stian, Halvorsen, Ole Johan, Akslen, Lars Andreas, Bahn, Duke, Pantel, Klaus, Riethdorf, Sabine, Ragde, Haakon, Gjertsen, Bjørn Tore, Øyan, Anne Margrete, Kalland, Karl-Henning, Beisland, Christian

“…Metastatic castration-resistant prostate cancer (mCRPC) is an immunologically cold disease with dismal outcomes. Cryoablation destroys cancer tissue, releases…”
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Context dependent regulatory patterns of the androgen receptor and androgen receptor target genes by Olsen, Jan Roger, Azeem, Waqas, Hellem, Margrete Reime, Marvyin, Kristo, Hua, Yaping, Qu, Yi, Li, Lisha, Lin, Biaoyang, Ke, Xi- Song, Øyan, Anne Margrete, Kalland, Karl- Henning

“…Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial…”
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Identification and distribution of nitric oxide synthase in the brain of adult zebrafish by Holmqvist, Bo, Ellingsen, Berit, Alm, Per, Forsell, Johan, Øyan, Anne-Margrete, Goksøyr, Anders, Fjose, Anders, Seo, Hee-Chan

“…Nitric oxide (NO) is proposed to be involved in developmental and plastic processes. We investigated the presence and distribution of nitric oxide synthase…”
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Proteomic profiling of endometrioid endometrial cancer reveals differential expression of hormone receptors and MAPK signaling proteins in obese versus non-obese patients by Mauland, Karen Klepsland, Ju, Zhenlin, Tangen, Ingvild Løberg, Berg, Anna, Kalland, Karl-Henning, Øyan, Anne Margrete, Bjørge, Line, Westin, Shannon N, Krakstad, Camilla, Trovik, Jone, Mills, Gordon B, Hoivik, Erling A, Johanna Werner, Henrica Maria

“…Endometrial cancer development is strongly linked to obesity, but knowledge regarding the influence of excess weight on endometrial tumor signaling pathways…”
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Proteasome-Mediated Regulation of GATA2 Expression and Androgen Receptor Transcription in Benign Prostate Epithelial Cells by Azeem, Waqas, Olsen, Jan Roger, Hellem, Margrete Reime, Hua, Yaping, Marvyin, Kristo, Ke, Xisong, Øyan, Anne Margrete, Kalland, Karl-Henning

“…GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign…”
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Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90 by Ryningen, Anita, Ersvær, Elisabeth, Øyan, Anne Margrete, Kalland, Karl-Henning, Vintermyr, Olav Karsten, Gjertsen, Bjørn Tore, Bruserud, Øystein

“…Spontaneous in vitro apoptosis reflects a true biological heterogeneity between patients which has to be considered when in vitro models are used to study…”
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Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors by STAPNES, Camilla, RYNINGEN, Anita, HATFIELD, Kimberley, ØYAN, Anne Margrete, EIDE, Geir Egil, CORBASCIO, Matthias, KALLAND, Karl-Henning, GJERTSEN, Bjørn Tore, BRUSERUD, Øystein

“…Modulation of gene expression through histone deacetylase (HDAC) inhibition is considered a possible therapeutic strategy in acute myeloid leukaemia (AML). In…”
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Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia by Øyan, Anne Margrete, Anensen, Nina, Bø, Trond Hellem, Stordrange, Laila, Jonassen, Inge, Bruserud, Øystein, Kalland, Karl-Henning, Gjertsen, Bjørn Tore

“…The molecular changes in vivo in acute myeloid leukemia cells early after start of conventional genotoxic chemotherapy are incompletely understood, and it is…”
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ERG upregulation and related ETS transcription factors in prostate cancer by Rostad, Kari, Mannelqvist, Monica, Halvorsen, Ole Johan, Oyan, Anne Margrete, Bø, Trond Hellem, Stordrange, Laila, Olsen, Sue, Haukaas, Svein Andreas, Lin, Biaoyang, Hood, Leroy, Jonassen, Inge, Akslen, Lars Andreas, Kalland, Karl-Henning

“…The aim of this study was to identify and validate differentially expressed genes in matched pairs of benign and malignant prostate tissue. Samples included 29…”
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