Search Results - "Østrup Jensen, Peter"

Bacterial biofilms predominate in both acute and chronic human lung infections by Kolpen, Mette, Kragh, Kasper Nørskov, Enciso, Juan Barraza, Faurholt-Jepsen, Daniel, Lindegaard, Birgitte, Egelund, Gertrud Baunbæk, Jensen, Andreas Vestergaard, Ravn, Pernille, Mathiesen, Inger Hee Mabuza, Gheorge, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, Tavs, Whiteley, Marvin, Jensen, Peter Østrup, Bjarnsholt, Thomas

“…A basic paradigm of human infection is that acute bacterial disease is caused by fast growing planktonic bacteria while chronic infections are caused by…”
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Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms by CHIANG, Wen-Chi, NILSSON, Martin, JENSEN, Peter Østrup, HØIBY, Niels, NIELSEN, Thomas E, GIVSKOV, Michael, TOLKER-NIELSEN, Tim

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Immune Responses to Pseudomonas aeruginosa Biofilm Infections by Moser, Claus, Jensen, Peter Østrup, Thomsen, Kim, Kolpen, Mette, Rybtke, Morten, Lauland, Anne Sofie, Trøstrup, Hannah, Tolker-Nielsen, Tim

“…is a key pathogen of chronic infections in the lungs of cystic fibrosis patients and in patients suffering from chronic wounds of diverse etiology. In these…”
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Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients by Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, Mark J., Pedersen, Jette, Hansen, Christine Rønne, Andersen, Claus Bøgelund, Pressler, Tacjana, Givskov, Michael, Høiby, Niels

“…The present study was undertaken to investigate the appearance and location of Pseudomonas aeruginosa in the cystic fibrosis (CF) lung and in sputum. Samples…”
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Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes by Alhede, Maria, Lorenz, Melanie, Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, Hans Christian, Bay, Lene, Bjarnsholt, Thomas

“…The ability of bacteria to aggregate and form biofilms impairs phagocytosis by polymorphonuclear leukocytes (PMNs). The aim of this study was to examine if the…”
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Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing by Jakobsen, Tim Holm, van Gennip, Maria, Phipps, Richard Kerry, Shanmugham, Meenakshi Sundaram, Christensen, Louise Dahl, Alhede, Morten, Skindersoe, Mette Eline, Rasmussen, Thomas Bovbjerg, Friedrich, Karlheinz, Uthe, Friedrich, Jensen, Peter Østrup, Moser, Claus, Nielsen, Kristian Fog, Eberl, Leo, Larsen, Thomas Ostenfeld, Tanner, David, Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael

“…In relation to emerging multiresistant bacteria, development of antimicrobials and new treatment strategies of infections should be expected to become a…”
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Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model by Cao, Bao, Christophersen, Lars, Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus, Sams, Thomas

“…Microbial cells embedded in a self-produced extracellular biofilm matrix cause chronic infections, e. g. by Pseudomonas aeruginosa in the lungs of cystic…”
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Why chronic wounds will not heal: a novel hypothesis by Bjarnsholt, Thomas, Kirketerp-Møller, Klaus, Jensen, Peter Østrup, Madsen, Kit G., Phipps, Richard, Krogfelt, Karen, Høiby, Niels, Givskov, Michael

“…ABSTRACT The present paper presents a hypothesis aimed at explaining why venous leg ulcers, pressure ulcers, and diabetic foot ulcers develop into a chronic…”
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Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm by Alhede, Morten, Kragh, Kasper Nørskov, Qvortrup, Klaus, Allesen-Holm, Marie, van Gennip, Maria, Christensen, Louise D, Jensen, Peter Østrup, Nielsen, Anne K, Parsek, Matt, Wozniak, Dan, Molin, Søren, Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael, Bjarnsholt, Thomas

“…For a chronic infection to be established, bacteria must be able to cope with hostile conditions such as low iron levels, oxidative stress, and clearance by…”
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Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment by Thomsen, Kim, Kobayashi, Osamu, Kishi, Kenji, Shirai, Ryo, Østrup Jensen, Peter, Heydorn, Arne, Hentzer, Morten, Calum, Henrik, Christophersen, Lars, Høiby, Niels, Moser, Claus

“…Animal models of human diseases are invaluable and inevitable elements in identifying and testing novel treatments for serious diseases, including severe…”
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Sublethal Ciprofloxacin Treatment Leads to Rapid Development of High-Level Ciprofloxacin Resistance during Long-Term Experimental Evolution of Pseudomonas aeruginosa by JØRGENSEN, Karin Meinike, WASSERMANN, Tina, JENSEN, Peter Østrup, WANG HENGZUANG, MOLIN, Søren, HØIBY, Niels, CIOFU, Oana

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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection by Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus, Hansen, Christine Rønne, Liengaard, Lars, Kharazmi, Arsalan, Pressler, Tanja, Høiby, Niels, Jensen, Peter Østrup

“…Chronic lung infection by Pseudomonas aeruginosa is the major severe complication in cystic fibrosis (CF) patients, where P. aeruginosa persists and grows in…”
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Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection by Jensen, Peter Østrup, Olsen, Pernille, Dungu, Arnold Matovu, Egelund, Gertrud Baunbæk, Jensen, Andreas Vestergaard, Ravn, Pernille, Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt‐Jepsen, Daniel, Kolpen, Mette

“…Bacterial aerobic respiration may determine the outcome of antibiotic treatment in experimental settings, but the clinical relevance of bacterial aerobic…”
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Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients by Kolpen, Mette, Dalby Sørensen, Christian, Faurholt‐Jepsen, Daniel, Hertz, Frederik Boëtius, Jensen, Peter Østrup, Bestle, Morten Heiberg

“…The aim of this study was to assess L‐lactate and D‐lactate in endotracheal aspirate from intubated patients hospitalized at the intensive care unit and…”
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Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients by Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, Richard, Nielsen, Anne Kirstine, Rybtke, Morten Theil, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana

“…Pseudomonas aeruginosa is the predominant microorganism in chronic lung infection of cystic fibrosis patients. The chronic lung infection is preceded by…”
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Interactions between Polymorphonuclear Leukocytes and Pseudomonas aeruginosa Biofilms on Silicone Implants In Vivo by GENNIP, Maria Van, DAHL CHRISTENSEN, Louise, ALHEDE, Morten, QVORTRUP, Klaus, ØSTRUP JENSEN, Peter, HØIBY, Niels, GIVSKOV, Michael, BJARNSHOLT, Thomas

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Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis by Nielsen, Bibi Uhre, Kolpen, Mette, Jensen, Peter Ostrup, Katzenstein, Terese, Pressler, Tacjana, Ritz, Christian, Mathiesen, Inger Hee Mabuza, Faurholt-Jepsen, Daniel

“…Background Markers of lung inflammation measured directly in expectorated sputum have the potential of improving the timing of antibiotic treatment in cystic…”
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Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus by Schwartz, Franziska A., Lerche, Christian J., Christophersen, Lars, Jensen, Peter Østrup, Laulund, Anne Sofie, Woetmann, Anders, Høiby, Niels, Moser, Claus

“…Staphylococcus aureus (SA) causes superficial and severe endovascular infections. The present in vitro study investigates the anti‐SA mechanisms of hyperbaric…”
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Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms by Gade, Peter Alexander Vistar, Olsen, Terkel Bo, Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, Kaj-Åge, Sams, Thomas

“…In chronic lung infections by Pseudomonas aeruginosa (PA) the bacteria thrive in biofilm structures protected from the immune system of the host and from…”
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In memoriam Elisabeth Ralfkiær 30.10.1950–11.07.2020 by Jensen, Louise Kruse, Bjarnsholt, Thomas, Jensen, Peter Østrup, Norrild, Bodil

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