Search Results - "Ødegaard Nielsen, Mette"

Alterations of the Brain Reward System in Antipsychotic Naïve Schizophrenia Patients by Nielsen, Mette Ødegaard, Rostrup, Egill, Wulff, Sanne, Bak, Nikolaj, Lublin, Henrik, Kapur, Shitij, Glenthøj, Birte

“…Background Various schizophrenic symptoms are suggested to be linked to a dysfunction of the brain reward system. Several studies have found alterations in the…”
Get full text

Alterations of Intrinsic Connectivity Networks in Antipsychotic-Naïve First-Episode Schizophrenia by Anhøj, Simon, Ødegaard Nielsen, Mette, Jensen, Maria Høj, Ford, Kristin, Fagerlund, Birgitte, Williamson, Peter, Glenthøj, Birte, Rostrup, Egill

“…The investigation of large-scale intrinsic connectivity networks in antipsychotic-naïve first-episode schizophrenia increases our understanding of system-level…”
Get full text

Reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels by Tangmose, Karen, Rostrup, Egill, Bojesen, Kirsten B, Sigvard, Anne, Jessen, Kasper, Johansen, Louise Baruël, Glenthøj, Birte Y, Nielsen, Mette Ødegaard

“…Aberrant anticipation of motivational salient events and processing of outcome evaluation in striatal and prefrontal regions have been suggested to underlie…”
Get more information

Differential effects of age at illness onset on verbal memory functions in antipsychotic-naïve schizophrenia patients aged 12-43 years by Fagerlund, Birgitte, Pantelis, Christos, Jepsen, Jens Richardt Møllegaard, Raghava, Jayachandra Mitta, Rostrup, Egill, Thomas, Marie Bjerregaard, Nielsen, Mette Ødegaard, Bojesen, Kirsten, Jensen, Karsten Gjessing, Stentebjerg-Decara, Marie, Klauber, Dea Gowers, Rudå, Ditte, Ebdrup, Bjørn H, Jessen, Kasper, Sigvard, Anne, Tangmose, Karen, Jeppesen, Pia, Correll, Christoph U, Fink-Jensen, Anders, Pagsberg, Anne Katrine, Glenthøj, Birte Yding

“…The typical onset of schizophrenia coincides with the maturational peak in cognition; however, for a significant proportion of patients the onset is before age…”
Get more information

Effect of the GLP-1 receptor agonist semaglutide on metabolic disturbances in clozapine-treated or olanzapine-treated patients with a schizophrenia spectrum disorder: study protocol of a placebo-controlled, randomised clinical trial (SemaPsychiatry) by Sass, Marie Reeberg, Danielsen, Andreas Aalkjær, Köhler-Forsberg, Ole, Storgaard, Heidi, Knop, Filip K, Nielsen, Mette Ødegaard, Sjödin, Anders Mikael, Mors, Ole, Correll, Christoph U, Ekstrøm, Claus, Vinberg, Maj, Nielsen, Jimmi, Vilsbøll, Tina, Fink-Jensen, Anders

“…IntroductionClozapine and olanzapine are some of the most effective antipsychotics, but both are associated with weight gain and relevant metabolic…”
Get full text

Differential Effects of Aripiprazole and Amisulpride on Negative and Cognitive Symptoms in Patients With First-Episode Psychoses by Nielsen, Mette Ødegaard, Kristensen, Tina Dam, Borup Bojesen, Kirsten, Glenthøj, Birte Y, Lemvigh, Cecilie K, Ebdrup, Bjørn H

“…Aripiprazole is hypothesized to have an effect on negative and cognitive symptoms in schizophrenia. Likewise, amisulpride is one of the only second-generation…”
Get full text

Associations of neural processing of reward with posttraumatic stress disorder and secondary psychotic symptoms in trauma-affected refugees by Uldall, Sigurd Wiingaard, Nielsen, Mette Ødegaard, Carlsson, Jessica, Glenthøj, Birte, Siebner, Hartwig Roman, Madsen, Kristoffer Hougaard, Madsen, Camilla Gøbel, Leffers, Anne-Mette, Nejad, Ayna Baladi, Rostrup, Egill

“…Background: Psychological traumatic experiences can lead to posttraumatic stress disorder (PTSD). Secondary psychotic symptoms are not common but may occur…”
Get full text

Reward Processing as an Indicator of Vulnerability or Compensatory Resilience in Psychoses? Results From a Twin Study by Nielsen, Mette Ødegaard, Rostrup, Egill, Hilker, Rikke, Legind, Christian, Anhøj, Simon, Robbins, Trevor William, Sahakian, Barbara J., Fagerlund, Birgitte, Glenthøj, Birte

“…Findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia. Twin…”
Get full text

Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis by Bojesen, Kirsten Borup, Broberg, Brian Villumsen, Fagerlund, Birgitte, Jessen, Kasper, Thomas, Marie Bjerregaard, Sigvard, Anne, Tangmose, Karen, Nielsen, Mette Ødegaard, Andersen, Gitte Saltoft, Larsson, Henrik Bo Wiberg, Edden, Richard A.E., Rostrup, Egill, Glenthøj, Birte Yding

“…Abnormal glutamate and GABA (gamma-aminobutyric acid) levels have been found in the early phase of schizophrenia and may underlie cognitive deficits. However,…”
Get full text

Clinical response to treatment with a partial dopamine agonist is related to changes in reward processing by Tangmose, Karen, Rostrup, Egill, Bojesen, Kirsten Borup, Sigvard, Anne, Glenthøj, Birte Y., Nielsen, Mette Ødegaard

“…•Psychoses have been linked to altered activity in the brain reward system.•Antipsychotic medication antagonizing dopamine D2-recepters normalize these…”
Get full text

Dopaminergic Activity in Antipsychotic-Naïve Patients Assessed With Positron Emission Tomography Before and After Partial Dopamine D2 Receptor Agonist Treatment: Association With Psychotic Symptoms and Treatment Response by Sigvard, Anne Korning, Nielsen, Mette Ødegaard, Gjedde, Albert, Bojesen, Kirsten Borup, Fuglø, Dan, Tangmose, Karen, Kumakura, Yoshitaka, Heltø, Kim, Ebdrup, Bjørn H., Jensen, Lars Thorbjørn, Rostrup, Egill, Glenthøj, Birte Yding

“…Dopamine activity has been associated with the response to antipsychotic treatment. Our study used a four-parameter model to test the association between the…”
Get full text

Validation of the Danish version of the brief negative symptom scale by Gehr, Johannes, Glenthøj, Birte, Ødegaard Nielsen, Mette

“…Objective: The Brief Negative Symptom Scale (BNSS) is an instrument for evaluating negative symptoms (NS) in schizophrenia based on the 2005 consensus…”
Get full text

Associations between cortical thickness and auditory verbal hallucinations in patients with schizophrenia: A systematic review by Köse, Güldas, Jessen, Kasper, Ebdrup, Bjørn H., Nielsen, Mette Ødegaard

“…•Six studies assessed cortical thickness in patients with AVH.•They consistently reported cortical thinning in temporal regions.•Several other regions were…”
Get full text

Clinical experiences of guided tapering of antipsychotics for patients with schizophrenia- a case series by Mølgaard, Sofie Norlin, Nielsen, Mette Ødegaard, Roed, Kickan, Nielsen, Jimmi

“…80% of patients value information on treatment options as an important part of recovery, further patients with a history of psychotic episodes feel excluded…”
Get full text

Striatal D 2/3 Binding Potential Values in Drug-Naïve First-Episode Schizophrenia Patients Correlate With Treatment Outcome by Wulff, Sanne, Pinborg, Lars Hageman, Svarer, Claus, Jensen, Lars Thorbjørn, Nielsen, Mette Ødegaard, Allerup, Peter, Bak, Nikolaj, Rasmussen, Hans, Frandsen, Erik, Rostrup, Egill, Glenthøj, Birte Yding

Get full text

Negative Symptoms and Reward Disturbances in Schizophrenia Before and After Antipsychotic Monotherapy by Nielsen, Mette Ødegaard, Rostrup, Egill, Broberg, Brian Villumsen, Wulff, Sanne, Glenthøj, Birte

“…Background. Negative symptoms (NS) are a central part of the symptomatology of schizophrenia, which is highly correlated to the functional outcome…”
Get full text

Increased use of coercive procedures and prolonged hospitalization in compulsory admitted psychotic patients, who refuse antipsychotic medication by Nielsen, Mette Ødegaard, Milting, Kristina, Brandt-Christensen, Anne Mette, Ebdrup, Bjørn H

“…Current Danish legislation imposes that compulsory admitted psychotic patients have the right to refuse antipsychotic medication, which markedly delays…”
Get full text

Electrophysiological and Neuroimaging Research on Negative Symptoms: Future Challenges by Mucci, Armida, Üçok, Alp, Nielsen, Mette Ødegaard

“…Negative symptoms are highly prevalent in subjects with schizophrenia and are associated with poor functional outcome.1-7 Primary negative symptoms are an…”
Get full text

Dopamine Synthesis Capacity and GABA and Glutamate Levels Separate Antipsychotic-Naïve Patients With First-Episode Psychosis From Healthy Control Subjects in a Multimodal Prediction Model by Sigvard, Anne K., Bojesen, Kirsten Borup, Ambrosen, Karen S., Nielsen, Mette Ødegaard, Gjedde, Albert, Tangmose, Karen, Kumakura, Yoshitaka, Edden, Richard, Fuglø, Dan, Jensen, Lars Thorbjørn, Rostrup, Egill, Ebdrup, Bjørn H., Glenthøj, Birte Yding

“…Disturbances in presynaptic dopamine activity and levels of GABA (gamma-aminobutyric acid) and glutamate plus glutamine collectively may have a role in the…”
Get full text

The impact of weight gain on antipsychotic nonadherence or discontinuation: A systematic review and meta-analysis by De, Riddhita, Smith, Emily C C, Navagnanavel, Janani, Au, Emily, Maksyutynska, Kateryna, Papoulias, Maria, Singh, Raghunath, Panganiban, Kristoffer J, Humber, Bailey, Mohr, Grimur Høgnason, Nielsen, Mette Ødegaard, Ebdrup, Bjørn H, Remington, Gary, Agarwal, Sri Mahavir, Hahn, Margaret K

“…Nonadherence/discontinuation of antipsychotic (AP) medications represents an important clinical issue in patients across psychiatric disorders, including…”
Get full text