Search Results - "Öztürk, Narin"

Reproductive effects of subchronic exposure to acetamiprid in male rats by Arıcan, Emre Yağmur, Gökçeoğlu Kayalı, Damla, Ulus Karaca, Bahar, Boran, Tuğçe, Öztürk, Narin, Okyar, Alper, Ercan, Feriha, Özhan, Gül

“…Acetamiprid, a selective agonist of nicotinic acetylcholine recetors, is one of the most widely used neonicotinoids. There is limited data about toxicity of…”
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Molecular Aspects of Circadian Pharmacology and Relevance for Cancer Chronotherapy by Ozturk, Narin, Ozturk, Dilek, Kavakli, Ibrahim Halil, Okyar, Alper

“…The circadian timing system (CTS) controls various biological functions in mammals including xenobiotic metabolism and detoxification, immune functions, cell…”
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A new validated high‐performance liquid chromatography method for the determination of regorafenib in rat plasma: Application for pharmacokinetic study by Aydoğmuş, Zeynep, Yılmaz, Ece Merve, Öztürk Seyhan, Narin, Okyar, Alper

“…This study reports a rapid and sensitive reversed‐phase high‐performance liquid chromatography method with ultraviolet detection for the determination of…”
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A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude by Doruk, Yagmur Umay, Yarparvar, Darya, Akyel, Yasemin Kubra, Gul, Seref, Taskin, Ali Cihan, Yilmaz, Fatma, Baris, Ibrahim, Ozturk, Nuri, Türkay, Metin, Ozturk, Narin, Okyar, Alper, Kavakli, Ibrahim Halil

“…Proper function of many physiological processes requires a robust circadian clock. Disruptions of the circadian clock can result in metabolic diseases, mood…”
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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice by Gul, Seref, Akyel, Yasemin Kubra, Gul, Zeynep Melis, Isin, Safak, Ozcan, Onur, Korkmaz, Tuba, Selvi, Saba, Danis, Ibrahim, Ipek, Ozgecan Savlug, Aygenli, Fatih, Taskin, Ali Cihan, Akarlar, Büşra Aytül, Ozlu, Nurhan, Ozturk, Nuri, Ozturk, Narin, Ünal, Durişehvar Özer, Guzel, Mustafa, Turkay, Metin, Okyar, Alper, Kavakli, Ibrahim Halil

“…Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals…”
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Dosing‐time, feeding, and sex‐dependent variations of everolimus pharmacokinetics in mice by Ozturk Civelek, Dilek, Ozturk Seyhan, Narin, Akyel, Yasemin Kubra, Gazioglu, Isil, Pala Kara, Zeliha, Orman, Mehmet N., Okyar, Alper

“…Background Everolimus is an oral mammalian target of rapamycin (mTOR) inhibitor used as an immunosuppressant and anticancer. Its pharmacokinetics is highly…”
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The effect of terpenes on percutaneous absorption of tiaprofenic acid gel by Okyar, Alper, Nuriyev, Maksat, Yildiz, Ayca, Pala-Kara, Zeliha, Ozturk, Narin, Kaptan, Engin

“…Tiaprofenic acid is a potent analgesic and nonsteroidal anti-inflammatory drug (NSAID) and like any other nonsteroidal anti-inflammatory drug, oral…”
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Ağız içi dijital tarayıcı ile elde edilen dental modellerin geleneksel alçı modeller ile karşılaştırılması by Öztürk,Narin, Akçam,Mehmet Okan

“…Bu çalışmada amacımız, dijital ortodontik modellerin güvenilirliğini test etmek, geleneksel alçı modeller ile boyutsal hassasiyet karşılaştırılmasını…”
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Diurnal Changes in Capecitabine Clock-Controlled Metabolism Enzymes Are Responsible for Its Pharmacokinetics in Male Mice by Akyel, Yasemin Kubra, Ozturk Civelek, Dilek, Ozturk Seyhan, Narin, Gul, Seref, Gazioglu, Isil, Pala Kara, Zeliha, Lévi, Francis, Kavakli, Ibrahim Halil, Okyar, Alper

“…The circadian timing system controls absorption, distribution, metabolism, and elimination processes of drug pharmacokinetics over a 24-h period. Exposure of…”
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Türkiye denizlerinde zehirli denizanaları ve toksik etkileri by İşinibilir Okyar,Melek, Okyar,Alper, Öztürk,Narin

“…Akdeniz, hem yerli hem de yabancı çeşitli denizanası türlerine ev sahipliği yapmaktadır. Son yıllarda, çoğunlukla kıyı bölgelerimizde meydana gelen aşırı…”
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The effects of P-glycoprotein inhibitor zosuquidar on the sex and time-dependent pharmacokinetics of parenterally administered talinolol in mice by Pala Kara, Zeliha, Ozturk Civelek, Dilek, Ozturk, Narin, Okyar, Alper

“…P-glycoprotein (P-gp) is an efflux protein that forms a tissue barrier and plays a role in the pharmacokinetics of drugs, limiting the influx of them and other…”
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Dosing-time dependent testicular toxicity of everolimus in mice by Ozturk, Narin, Ozturk Civelek, Dilek, Sancar, Serap, Kaptan, Engin, Pala Kara, Zeliha, Okyar, Alper

“…The circadian timing system controls many biological functions in mammals including drug metabolism and detoxification, cell cycle events, and thus may affect…”
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Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling by Okyar, Alper, Kumar, Swati A., Filipski, Elisabeth, Piccolo, Enza, Ozturk, Narin, Xandri-Monje, Helena, Pala, Zeliha, Abraham, Kristin, Gomes, Ana Rita Gato de Jesus, Orman, Mehmet N., Li, Xiao-Mei, Dallmann, Robert, Lévi, Francis, Ballesta, Annabelle

“…P-glycoprotein ( P-gp ) largely influences the pharmacokinetics (PK) and toxicities of xenobiotics in a patient-specific manner so that personalized drug…”
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VENOMOUS JELLYFISHES IN THE TURKISH SEAS AND THEIR TOXIC EFFECTS by İşinibilir, Melek, Okyar, Alper, Öztürk, Narin

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The immune system as a chronotoxicity target of the anticancer mTOR inhibitor everolimus by Ozturk, Narin, Ozturk, Dilek, Pala-Kara, Zeliha, Kaptan, Engin, Sancar-Bas, Serap, Ozsoy, Nurten, Cinar, Suzan, Deniz, Gunnur, Li, Xiao-Mei, Giacchetti, Sylvie, Lévi, Francis, Okyar, Alper

“…The circadian timing system controls many biological functions in mammals including xenobiotic metabolism, detoxification, cell proliferation, apoptosis and…”
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Optimization of irinotecan chronotherapy with P-glycoprotein inhibition by Filipski, Elisabeth, Berland, Elodie, Ozturk, Narin, Guettier, Catherine, van der Horst, Gijsbertus T.J., Lévi, Francis, Okyar, Alper

“…The relevance of P-glycoprotein (P-gp) for irinotecan chronopharmacology was investigated in female B6D2F1 mice. A three-fold 24h change in the mRNA expression…”
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