Search Results - "Öztürk, Mert Burak"

Use of Non-steroidal Anti-inflammatory Drugs for Chemoprevention of Inflammation-induced Prostate Cancer by Debeleç Bütüner, Bilge, Öztürk, Mert Burak

“…Chronic inflammation has been known as one of the major causes of cancer progression and 25% of cancer cases initiate due to chronic inflammation according to…”
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Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis by Debeleç-Bütüner, Bilge, Öztürk, Mert Burak, Tağ, Özgür, Akgün, İsmail Hakkı, Yetik-Anacak, Günay, Bedir, Erdal, Korkmaz, Kemal Sami

“…•9,19-cyclolanostane derivatives starting from cycloastragenol were synthesized.•Five analogs were selected to be screened for their anti-inflammatory…”
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Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells by Tan, Chris Soon Heng, Go, Ka Diam, Bisteau, Xavier, Dai, Lingyun, Yong, Chern Han, Prabhu, Nayana, Ozturk, Mert Burak, Lim, Yan Ting, Sreekumar, Lekshmy, Lengqvist, Johan, Tergaonkar, Vinay, Kaldis, Philipp, Sobota, Radoslaw M, Nordlund, Pär

“…Proteins differentially interact with each other across cellular states and conditions, but an efficient proteome-wide strategy to monitor them is lacking. We…”
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Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1 by Xu, Xueyong, Li, Yinghui, Bharath, Sakshibeedu R., Ozturk, Mert Burak, Bowler, Matthew W., Loo, Bryan Zong Lin, Tergaonkar, Vinay, Song, Haiwei

“…Transcriptional factors ETS1/2 and p52 synergize downstream of non-canonical NF-κB signaling to drive reactivation of the −146C>T mutant TERT promoter in…”
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Current Insights to Regulation and Role of Telomerase in Human Diseases by Ozturk, Mert Burak, Li, Yinghui, Tergaonkar, Vinay

“…The telomerase ribonucleoprotein complex has a pivotal role in regulating the proliferation and senescence of normal somatic cells as well as cancer cells…”
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CDK inhibitors–induced SSAT expression requires NFκB and PPARγ inMCF-7 breast cancer cells by OBAKAN, Pınar, YILDIRIM, Şeyma, ÖZTÜRK, Mert Burak, BERRAK, Özge, ÇOKER GÜRKAN, Ajda, ARISAN, Elif Damla, ÜNSAL, Zeynep Narçin

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Genome-wide screens identify specific drivers of mutant hTERT promoters by Shanmugam, Raghuvaran, Ozturk, Mert Burak, Low, Joo-Leng, Akincilar, Semih Can, Chua, Joelle Yi Heng, Thangavelu, Matan Thangavelu, Periyasamy, Giridharan, DasGupta, Ramanuj, Tergaonkar, Vinay

“…Cancer-specific promoter mutations reported in 19% of cancers result in enhanced telomerase activity. Understanding the distinctions between transcriptional…”
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Identification of Novel Transcriptional Modulators of Oncogenesis by Ozturk, Mert Burak

“…Oncogenesis is the process by which cells undergo a series of genetic and cellular changes and enable unlimited proliferation. Healthy cells have developed…”
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HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate by Hamid, Syed Muhammad, Cicek, Seher, Karamil, Selda, Ozturk, Mert Burak, Debelec-Butuner, Bilge, Erbaykent-Tepedelen, Burcu, Varisli, Lokman, Gonen-Korkmaz, Ceren, Yorukoglu, Kutsal, Korkmaz, Kemal Sami

“…•HOXB13 is a homeobox protein that is expressed in normal adult prostate and in cancer.•HOXB13 physically associates with cyclin D1 and cyclin B1.•HOXB13…”
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Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention by Bilge Debelec-Butuner, Mert Burak Ozturk, Ozgur Tag, Ismail Hakki Akgun, Erdal Bedir, Kemal Sami Korkmaz

“…Inhibition of inflammation-induced carcinogenesis is an efficient therapeutic strategy for cancer chemoprevention as use of anti-inflammatories was reported to…”
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