Search Results - "Özsavcı, Derya"

Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells by Kulabaş, Necla, Tatar, Esra, Bingöl Özakpınar, Özlem, Özsavcı, Derya, Pannecouque, Christophe, De Clercq, Erik, Küçükgüzel, İlkay

“…In this study, a series of thiosemicarbazide derivatives 12–14, 1,2,4-triazol-3-thione derivatives 15–17 and compounds bearing…”
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Melatonin protects against ischemic heart failure in rats by Şehirli, Ahmet Özer, Koyun, Derya, Tetik, Şermin, Özsavcı, Derya, Yiğiner, Ömer, Çetinel, Şule, Tok, Olgu Enis, Kaya, Zehra, Akkiprik, Mustafa, Kılıç, Ertugrul, Şener, Göksel

“…Ischemic injury, which occurs as a result of sympathetic hyperactivity, plays an important role in heart failure. Melatonin is thought to have antiatherogenic,…”
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Effects of dapagliflozin in experimental sepsis model in rats by Kingir, Zehra Betül, Özdemir Kural, Zarife Nigar, Cam, Muhammet Emin, Cilingir, Ozlem Tugce, Şekerler, Turgut, Ercan, Feriha, Bingöl Özakpınar, Özlem, Ozsavci, Derya, Sancar, Mesut, Okuyan, Betul

“…The aim of this study was to evaluate the possible protective effects of dapagliflozin in an experimental sepsis model in rats. Saline (1 mL/kg, p.o.) or…”
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Synthesis of Diflunisal Thiazolidinones as Anticancer Agents by Şenkardeş, Sevil, Özakpınar, Özlem B, Özsavcı, Derya, Şener, Azize, Çevik, Özge, Küçükgüzel, Ş Güniz

“…A series of diflunisal 4-thiazolidinones were synthesized. Some selected compounds were determined at one dose towards the full panel of 60 human cancer cell…”
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Melatonin treatment protects against spinal cord injury induced functional and biochemical changes in rat urinary bladder by Erşahin, Mehmet, Özdemir, Zarife, Özsavcı, Derya, Akakın, Dilek, Yeğen, Berrak Ç., Reiter, Russel J., Şener, Göksel

“…:  Oxidative stress induced by spinal cord injury (SCI) has deleterious effects on the function of several organ systems including the urinary bladder. In this…”
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Obestatin alleviates subarachnoid haemorrhage-induced oxidative injury in rats via its anti-apoptotic and antioxidant effects by Er ahin, Mehmet, Özsavc, Derya, ener, Azize, Özakp nar, Özlem Bingöl, Toklu, Hale Zerrin, Akakin, Dilek, ener, Göksel, Ye en, Berrak Ç.

“…Abstract Objective: The aim was to investigate the putative anti-inflammatory and anti-apoptotic effect of obestatin in a rat model of subarachnoidal…”
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The Novel Function of Nesfatin-1 as an Anti-inflammatory and Antiapoptotic Peptide in Subarachnoid Hemorrhage–Induced Oxidative Brain Damage in Rats by Özsavcí, Derya, Erşahin, Mehmet, Şener, Azize, Özakpinar, Özlem Bingol, Toklu, Hale Z., Akakín, Dilek, Şener, Göksel, Yeğen, Berrak Ç

“…Abstract BACKGROUND: There is substantial evidence to suggest that oxidative stress plays a significant role in the development of acute brain injury after…”
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New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects by Özsavcı, Derya, Şener, Azize, Oba, Rabia, Yanıkkaya Demirel, Gülderen, Uras, Fikriye, Yardımcı, Turay Kevser

“…We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite,…”
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Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents by Küçükgüzel, Ş Güniz, Coşkun, İnci, Aydın, Sevil, Aktay, Göknur, Gürsoy, Şule, Çevik, Özge, Özakpınar, Özlem Bingöl, Özsavcı, Derya, Şener, Azize, Kaushik-Basu, Neerja, Basu, Amartya, Talele, Tanaji T

“…A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamides…”
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Carbon Nanofiber-Sodium Alginate Composite Aerogels Loaded with Vitamin D: The Cytotoxic and Apoptotic Effects on Colon Cancer Cells by Bingol Ozakpinar, Ozlem, Dastan, Havva, Gurboga, Merve, Sayin, Fatih Serdar, Ozsavci, Derya, Caliskan Salihi, Elif

“…Colorectal cancer (CRC) is the fourth most commonly diagnosed cancer and the third leading cause of cancer-related deaths worldwide. A substantial body of…”
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Nesfatin-1 improves oxidative skin injury in normoglycemic or hyperglycemic rats by Solmaz, Ali, Bahadır, Elif, Gülçiçek, Osman B., Yiğitbaş, Hakan, Çelik, Atilla, Karagöz, Ayça, Özsavcı, Derya, Şirvancı, Serap, Yeğen, Berrak Ç.

“…•Nesfatin-1 improved oxidative skin injury induced by surgical wound.•Nesfatin-1 facilitated wound healing in non-diabetic and diabetic rats.•Nesfatin-1…”
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Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells by Küçükgüzel, Ş. Güniz, Koç, Derya, Çıkla-Süzgün, Pelin, Özsavcı, Derya, Bingöl-Özakpınar, Özlem, Mega-Tiber, Pınar, Orun, Oya, Erzincan, Pınar, Sağ-Erdem, Safiye, Şahin, Fikrettin

“…Tolmetin hydrazide and a novel series of tolmetin hydrazide–hydrazones 4a–l were synthesized in this study. The structures of the new compounds were determined…”
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Synthesis, Cytotoxicity, and Pro-Apoptosis Activity of Etodolac Hydrazide Derivatives as Anticancer Agents by Çıkla, Pelin, Özsavcı, Derya, Bingöl-Özakpınar, Özlem, Şener, Azize, Çevik, Özge, Özbaş-Turan, Suna, Akbuğa, Jülide, Şahin, Fikrettin, Küçükgüzel, Ş. Güniz

“…Etodolac hydrazide and a novel series of etodolac hydrazide‐hydrazones 3–15 and etodolac 4‐thiazolidinones 16–26 were synthesized in this study. The structures…”
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Level of clinical evidence of herbal complementary therapies in psychiatric disorders by Ozsavci, Derya, Ozakpinar, Ozlem Bingol, Cetin, Mesut, Aricioglu, Feyza

“…Psychiatric diseases including depression, anxiety, schizophrenia, and insomnia are common mental health problems with high economic and social costs…”
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Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid by Ekiz, Arif, Özdemir‐Kumral, Zarife Nigâr, Erşahin, Mehmet, Tuğtepe, Halil, Öğünç, Ayliz Velioğlu, Akakın, Dilek, Kıran, Demir, Özsavcı, Derya, Biber, Necat, Hakan, Tayfun, Yeğen, Berrak Ç., Şener, Göksel, Toklu, Hale Z.

“…BACKGROUND & AIM Alpha lipoic acid (LA) was shown to exert neuroprotection in trauma‐induced spinal cord injury (SCI), which is frequently associated with…”
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Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet–leukocyte aggregate formation occur simultaneously in hyperlipidemia? by Sener, Azize, Ozsavci, Derya, Oba, Rabia, Demirel, Gulderen Yanikkaya, Uras, Fikriye, Yardimci, K. Turay

“…The circulating lipoproteins may cause some abnormalities in platelet composition and function in hypercholesterolemia. The aim of this study was to…”
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New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects / Hiperlipidemili ve saglikli olgularda trombositler uzerinde klopidogrelin yeni in vitro etkileri by Ozsavci, Derya, Sener, Azize, Oba, Rabia, Demirel, Gulderen Yanikkaya, Uras, Fikriye, Yardimci, Turay Kevser

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New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects by Derya Özsavcı, Azize Şener, Rabia Oba, Gülderen Yanıkkaya Demirel, Fikriye Uras, Turay Kevser Yardımcı

“…OBJECTIVE: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione,…”
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Ovarian stem cells： From basic to clinical applications by Ozakpinar, Ozlem Bingol, Maurer, Anne-Marie, Ozsavci, Derya

“…The field of reproductive biology has undergone significantdevelopments in the last decade. The notion thatthere is a fixed reserve pool of oocytes before…”
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Native High-Density Lipoprotein and Melatonin Improve Platelet Response Induced by Glycated Lipoproteins by Ozsavci, D, Nazli, A, Bingol Ozakpinar, O, Yanikkaya Demirel, G, Vanizor Kural, B, Sener, A

“…Activated platelets and glycated lipoproteins are responsible for atherothrombosis in diabetics. Melatonin and native high-density lipoproteins are crucial in…”
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